Polyomavirus Infections

Common Name(s)

Polyomavirus Infections

Polyomaviruses are a widespread group of small viruses that can harm people with weakened immune systems. The two most common polyomaviruses are the BK and JC (John Cunningham) viruses, for which eighty percent of the human population is protected from by having virus-specific antibodies. Symptoms of these viruses include tumors, but symptoms tend to only show in patients with poor immune systems and an inability to fight infection. The best treatment available is to find a way to improve the host's immune system. Doctors hope that by making the immune system stronger the infected person's body will be able to identify the virus and get rid of it on its own.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polyomavirus Infections" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Polyomavirus Infections" returned 10 free, full-text research articles on human participants. First 3 results:

Polyomavirus infections and its clinical relevance in cancer patients: A Prospective Study.
 

Author(s): Samah A Loutfy, Manar M Moneer, Salem E Salem, Emad A El-Moniem Abada, Entsar A El-Moniem Ahmed, Lamiaa H Ibrahim, El-Chaimaa B Mohamed

Journal: J Infect Public Health. ;10(1):22-30.

 

BK and JC polyomaviruses (PyV) have been demonstrated to be associated with the pathogenesis of various human cancers. We aimed to investigate the impact of BK and JC polyomavirus infections on several clinical parameters in different human cancers. A total of 150 cancer patients ...

Last Updated: 11 Mar 2016

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Human polyomavirus type six in respiratory samples from hospitalized children with respiratory tract infections in Beijing, China.
 

Author(s): Wen-Zhi Zheng, Tian-Li Wei, Fen-Lian Ma, Wu-Mei Yuan, Qian Zhang, Ya-Xin Zhang, Hong Cui, Li-Shu Zheng

Journal:

 

HPyV6 is a novel human polyomavirus (HPyV), and neither its natural history nor its prevalence in human disease is well known. Therefore, the epidemiology and phylogenetic status of HPyV6 must be systematically characterized.

Last Updated: 14 Oct 2015

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The Prevalence of Human Bocavirus, Human Coronavirus-NL63, Human Metapneumovirus, Human Polyomavirus KI and WU in Respiratory Tract Infections in Kuwait.
 

Author(s): Sahar Essa, Abdullah Owayed, Haya Altawalah, Mousa Khadadah, Nasser Behbehani, Widad Al-Nakib

Journal: Med Princ Pract. 2015 ;24(4):382-7.

 

The aim of this study was to investigate the prevalence of human coronavirus (HCoV)-NL63, human metapneumovirus (hMPV), human bocavirus (Boca), human polyomavirus KI (KIV) and human polyomavirus WU (WUV) in respiratory tract infections (RTI) in Kuwait.

Last Updated: 26 Jun 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Polyomavirus Infections" returned 2 free, full-text review articles on human participants. First 3 results:

Patterns of polyomavirus SV40 infections and associated cancers in humans: a model.
 

Author(s): Janet S Butel

Journal: Curr Opin Virol. 2012 Aug;2(4):508-14.

 

A model is described that predicts patterns of polyomavirus SV40 infections and associated cancers in humans. The model proposes that SV40 infections were established in humans primarily by exposure to contaminated oral poliovaccines and that infections persist today in geographic ...

Last Updated: 17 Aug 2012

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Murine polyomavirus virus-like particles (VLPs) as vectors for gene and immune therapy and vaccines against viral infections and cancer.
 

Author(s): Karin Tegerstedt, Andrea Vlastos Franzén, Kalle Andreasson, Jeanna Joneberg, Shirin Heidari, Torbjörn Ramqvist, Tina Dalianis

Journal: Anticancer Res.. ;25(4):2601-8.

 

This review describes the use of murine polyomavirus "virus-like" particles (MPyV-VLPs), free from viral genes, as vectors for gene and immune therapy and as vaccines. For large-scale MPyV-VLP manufacture, VP1 is produced in a baculovirus insect cell system, E. coli or in yeast. MPyV-VLPs ...

Last Updated: 5 Aug 2005

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Localized Radiation Therapy or Recombinant Interferon Beta and Avelumab With or Without Cellular Adoptive Immunotherapy in Treating Patients With Metastatic Merkel Cell Carcinoma
 

Status: Recruiting

Condition Summary: Merkel Cell Polyomavirus Infection; Stage IV Merkel Cell Carcinoma AJCC v7

 

Last Updated: 9 Nov 2017

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Involvement of Polyomaviruses in the Pathogenesis of Autoimmune Thyroiditis and Goitrigenesis.
 

Status: Recruiting

Condition Summary: Polyoma Virus Infection; Thyroiditis, Autoimmune

 

Last Updated: 5 Apr 2017

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Studies of Dermatologic Diseases Biospecimen Acquisition Protocol
 

Status: Recruiting

Condition Summary: Dermatologic Conditions; Healthy Volunteers; Normal Volunteers; Carcinoma, Merkel Cell

 

Last Updated: 21 Nov 2017

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