Portal hypertension

Common Name(s)

Portal hypertension

Portal hypertension is abnormally high blood pressure in branches of the portal vein, the large vein that brings blood from the intestine to the liver. Portal hypertension itself does not cause symptoms, but complications from the condition can lead to an enlarged abdomen, abdominal discomfort, confusion, drowsiness and internal bleeding. It may be caused by a variety of conditions, but cirrhosis is the most common cause in Western countries. Treatment is generally directed toward the cause of the condition, although emergency treatment is sometimes needed for serious complications.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Portal hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Portal hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Portal hypertension" returned 677 free, full-text research articles on human participants. First 3 results:

Idiopathic portal hypertension with regard to thiopurine treatment.
 

Author(s): Salvador Machlab, Mireia Miquel, Mercedes Vergara

Journal: Rev Esp Enferm Dig. 2018 06;110(6):409.

 

Idiopathic portal hypertension (IPH) is an infrequent adverse reaction to the use of thiopurines that tends to be overlooked. Herein, we present a patient with ileocolic Crohn's disease treated with azathioprine who presented ascites, esophageal varices and splenomegaly without any ...

Last Updated: 31 Dec 1969

Go To URL
Postoperative hemorrhage caused by portal hypertension associated with autoimmune pancreatitis: A case report.
 

Author(s): Puzi Wang, Rongli Xie, Zhifeng Zhao, Jiajun Ren, Jian Fei

Journal: Medicine (Baltimore). 2018 Feb;97(8):e9982.

 

Autoimmune pancreatitis is a form of chronic pancreatitis, characterized by diffused enlargement of the pancreas and irregular narrowing of the main pancreatic duct. The theory that portal hypertension is associated with autoimmune pancreatitis has not been emphasized. In addition, ...

Last Updated: 31 Dec 1969

Go To URL
Intentional Modulation of Portal Venous Pressure by Splenectomy Saves the Patient with Liver Failure and Portal Hypertension After Major Hepatectomy: Is Delayed Splenectomy an Acceptable Therapeutic Option for Secondary Portal Hypertension?
 

Author(s): Yuichi Takamatsu, Tomohide Hori, Takafumi Machimoto, Toshiyuki Hata, Yoshio Kadokawa, Tatsuo Ito, Shigeru Kato, Daiki Yasukawa, Yuki Aisu, Yusuke Kimura, Taku Kitano, Tsunehiro Yoshimura

Journal:

 

BACKGROUND Major or aggressively-extended hepatectomy (MAEH) may cause secondary portal hypertension (PH), and postoperative liver failure (POLF) and is often fatal. Challenges to prevent secondary PH and subsequent POLF, such as shunt creation and splenic arterial ligation, have ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Portal hypertension" returned 135 free, full-text review articles on human participants. First 3 results:

Bile Acids and Portal Hypertension
 

Author(s): Juan Pablo Arab, Francisco Barrera, Marco Arrese

Journal: Ann Hepatol. 2017 11;16(Suppl. 1: s3-105.):s83-s86.

 

The recent discovery of bile acid (BA) receptors and a better delineation of the multiple roles of BAs in relevant biological processes have revamped BA research. The vasoactive actions of BAs were recognized more than three decades ago but the underlying mechanisms of the BA-induced ...

Last Updated: 31 Dec 1969

Go To URL
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
 

Author(s): Thomas Reiberger, Andreas Püspök, Maria Schoder, Franziska Baumann-Durchschein, Theresa Bucsics, Christian Datz, Werner Dolak, Arnulf Ferlitsch, Armin Finkenstedt, Ivo Graziadei, Stephanie Hametner, Franz Karnel, Elisabeth Krones, Andreas Maieron, Mattias Mandorfer, Markus Peck-Radosavljevic, Florian Rainer, Philipp Schwabl, Vanessa Stadlbauer, Rudolf Stauber, Herbert Tilg, Michael Trauner, Heinz Zoller, Rainer Schöfl, Peter Fickert

Journal: Wien. Klin. Wochenschr.. 2017 Nov;129(Suppl 3):135-158.

 

The Billroth III guidelines were developed during a consensus meeting of the Austrian Society of Gastroenterology and Hepatology (ÖGGH) and the Austrian Society of Interventional Radiology (ÖGIR) held on 18 February 2017 in Vienna. Based on international guidelines and considering ...

Last Updated: 31 Dec 1969

Go To URL
Non-invasive diagnosis of portal hypertension in cirrhosis using ultrasound based elastography.
 

Author(s): Ivica Grgurevic, Tomislav Bokun, Tonci Bozin, Vladimir Matic, Sara Haberle, Ioan Sporea

Journal: Med Ultrason. 2017 May;19(3):310-317.

 

Liver stiffness measurement (LSM) by ultrasound-based elastography may be used to non-invasively discriminate between the stages of liver fibrosis, rule out cirrhosis and follow its evolution, including the prediction of the presence of oesophageal varices. The same is possible ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Low-grade Cirrhotic Portal Hypertension Due to Hepatitis B Virus With Fuzheng Huayu and Entecavir
 

Status: Not yet recruiting

Condition Summary: Portal Hypertension

 

Last Updated: 24 Oct 2016

Go to URL

Last Updated: 24 Oct 2016

Go to URL
Utility of EUS-elastography to Predict Portal Hypertension
 

Status: Recruiting

Condition Summary: Portal Hypertension

 

Last Updated: 18 Jul 2017

Go to URL