Portal hypertension

Common Name(s)

Portal hypertension

Portal hypertension is abnormally high blood pressure in branches of the portal vein, the large vein that brings blood from the intestine to the liver. Portal hypertension itself does not cause symptoms, but complications from the condition can lead to an enlarged abdomen, abdominal discomfort, confusion, drowsiness and internal bleeding. It may be caused by a variety of conditions, but cirrhosis is the most common cause in Western countries. Treatment is generally directed toward the cause of the condition, although emergency treatment is sometimes needed for serious complications.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Portal hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Portal hypertension" returned 672 free, full-text research articles on human participants. First 3 results:

Idiopathic portal hypertension with regard to thiopurine treatment.
 

Author(s): Salvador Machlab, Mireia Miquel, Mercedes Vergara

Journal: Rev Esp Enferm Dig. 2018 06;110(6):409.

 

Idiopathic portal hypertension (IPH) is an infrequent adverse reaction to the use of thiopurines that tends to be overlooked. Herein, we present a patient with ileocolic Crohn's disease treated with azathioprine who presented ascites, esophageal varices and splenomegaly without any ...

Last Updated: 31 Dec 1969

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Postoperative hemorrhage caused by portal hypertension associated with autoimmune pancreatitis: A case report.
 

Author(s): Puzi Wang, Rongli Xie, Zhifeng Zhao, Jiajun Ren, Jian Fei

Journal: Medicine (Baltimore). 2018 Feb;97(8):e9982.

 

Autoimmune pancreatitis is a form of chronic pancreatitis, characterized by diffused enlargement of the pancreas and irregular narrowing of the main pancreatic duct. The theory that portal hypertension is associated with autoimmune pancreatitis has not been emphasized. In addition, ...

Last Updated: 31 Dec 1969

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Sinistral Portal Hypertension Due to Pancreatic Hydatid Cyst.
 

Author(s): Tolga Canbak, Aylin Acar, Ali Ediz Kıvanç, Fatih Başak, Fatma Kulalı, Gürhan Baş

Journal: Turkiye Parazitol Derg. 2017 Dec;41(4):.

 

Hydatid disease is caused by Echinococcus granulosus. Hydatid cysts are commonly located in the liver and lungs. The occurrence of pancreatic hydatid cysts is very rare, even in endemic areas. Sinistral portal hypertension, which is rarely seen, occurs when a pathological process ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Portal hypertension" returned 134 free, full-text review articles on human participants. First 3 results:

Bile Acids and Portal Hypertension
 

Author(s): Juan Pablo Arab, Francisco Barrera, Marco Arrese

Journal: Ann Hepatol. 2017 11;16(Suppl. 1: s3-105.):s83-s86.

 

The recent discovery of bile acid (BA) receptors and a better delineation of the multiple roles of BAs in relevant biological processes have revamped BA research. The vasoactive actions of BAs were recognized more than three decades ago but the underlying mechanisms of the BA-induced ...

Last Updated: 31 Dec 1969

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Non-invasive diagnosis of portal hypertension in cirrhosis using ultrasound based elastography.
 

Author(s): Ivica Grgurevic, Tomislav Bokun, Tonci Bozin, Vladimir Matic, Sara Haberle, Ioan Sporea

Journal: Med Ultrason. 2017 May;19(3):310-317.

 

Liver stiffness measurement (LSM) by ultrasound-based elastography may be used to non-invasively discriminate between the stages of liver fibrosis, rule out cirrhosis and follow its evolution, including the prediction of the presence of oesophageal varices. The same is possible ...

Last Updated: 31 Dec 1969

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The Molecular Basis of Portal Hypertension.
 

Author(s): Don C Rockey

Journal: Trans. Am. Clin. Climatol. Assoc.. 2017 ;128():330-345.

 

Cirrhosis leads to portal hypertension and vascular abnormalities in multiple vascular beds. There is intense vasoconstriction in the liver and the kidneys, but also vasodilation in the other vascular beds, including the periphery, lungs, brain, and mesentery. The derangement in each ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Low-grade Cirrhotic Portal Hypertension Due to Hepatitis B Virus With Fuzheng Huayu and Entecavir
 

Status: Not yet recruiting

Condition Summary: Portal Hypertension

 

Last Updated: 24 Oct 2016

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Last Updated: 24 Oct 2016

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Utility of EUS-elastography to Predict Portal Hypertension
 

Status: Recruiting

Condition Summary: Portal Hypertension

 

Last Updated: 18 Jul 2017

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