Positive rheumatoid factor polyarthritis

Common Name(s)

Positive rheumatoid factor polyarthritis

Positive rheumatoid factor polyarthritis is one of the forms of juvenile arthritis, more specifically idiopathic arthritis, affecting children under 16 years old. Only 10 percent of children with polyarthritis are rheumatoid factor positive (RF-positive), which is an autoantibody similar to that found in adult rheumatoid arthritis. An autoantibody is an antibody directed against an organism’s own tissues, meaning your body’s immune system’s antibodies, which usually protects your health by neutralizing foreign substances such as bacteria and viruses, mistakenly attack your joints. Positive rheumatoid factor polyarthritis causes inflammation in five or more joints within the first 6 months of the disease and a positive blood test for rheumatoid factors (RF) helps to identify the condition.

Most children who are RF-positive are girls, usually aged 10 or older. Early treatment is important to slow down the disease and prevent long-term damage. This group can have quite a severe form of disease which needs to be actively treated with medication to avoid joint damage. This type of arthritis closely resembles rheumatoid arthritis as seen in adults.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Positive rheumatoid factor polyarthritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Positive rheumatoid factor polyarthritis" returned 1 free, full-text research articles on human participants. First 3 results:

Refractory rheumatoid factor positive polyarthritis in a female adolescent already suffering from type 1 diabetes mellitus and Hashimoto's thyroiditis successfully treated with etanercept.
 

Author(s): Alma Nunzia Olivieri, Dario Iafusco, Antonio Mellos, Angela Zanfardino, Angela Mauro, Carmela Granato, Maria Francesca Gicchino, Francesco Prisco, Laura Perrone

Journal:

 

Type 1 diabetes mellitus may be associated with many autoimmune diseases with the common autoimmune pathogenesis. We describe the case of a girl suffering from Type 1 diabetes mellitus and autoimmune Hashimoto's thyroiditis since the childhood and, due to the onset of Juvenile Idiopathic ...

Last Updated: 15 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Positive rheumatoid factor polyarthritis" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
 

Status: Recruiting

Condition Summary: Rheumatic Joint Disease

 

Last Updated: 6 Jun 2017

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