Precocious puberty

Common Name(s)

Precocious puberty

Precocious puberty is when a child goes through puberty too soon. Puberty is the physical changes a child goes through when their body is maturing into an adult body capable of reproduction. Precocious puberty is defined as a girl beginning puberty before age 8, and a boy reaching puberty before age 9. Symptoms in girls include breast growth and menstruation, while symptoms in boys include facial hair, deepening voice, and enlarged testicles. Both boys and girls will experience rapid growth, pubic and underarm hair, and acne. The causes of precocious puberty are not entirely known in most cases. In rare cases, tumors, infections, hormone disorders, or brain abnormalities may be the cause of precocious puberty. Treatment may include medications that help delay puberty.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Precocious puberty" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Precocious puberty" returned 208 free, full-text research articles on human participants. First 3 results:

Applicability of a novel mathematical model for the prediction of adult height and age at menarche in girls with idiopathic central precocious puberty.
 

Author(s): Mateus Cavarzan Lopes, Carolina Oliveira Ramos, Ana Claudia Latronico, Berenice B Mendonça, Vinicius N Brito

Journal:

 

Unfavorable predicted adult height and psychosocial inadequacy represent parameters used to guide therapeutic intervention in girls with central precocious puberty. Gonadotropin-releasing hormone analog is the first-line treatment. The aim of this study was to compare two methods ...

Last Updated: 31 Dec 1969

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[Beta-hCG-producing thymic teratoma: an uncommon cause of peripheral precocious puberty].
 

Author(s): Claudia Lozano C, Marcela Molina P

Journal: Rev Chil Pediatr. 2018 Jun;89(3):373-379.

 

Among the causes of peripheral precocious puberty in men are the beta-human cho rionic gonadotropin (Β-HCG)-secreting tumors, such as hepatoblastomas, dysgerminomas, chorio carcinomas, and immature teratomas. In pediatrics, the mediastinal teratomas are rare, representing the 7-10% ...

Last Updated: 31 Dec 1969

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The prevalence of brain abnormalities in boys with central precocious puberty may be overestimated.
 

Author(s): Jong Seo Yoon, Cheol Hwan So, Hae Sang Lee, Jung Sub Lim, Jin Soon Hwang

Journal:

 

Brain magnetic resonance imaging (MRI) is routinely performed to identify brain lesions in boys with central precocious puberty (CPP). We investigated the prevalence of CPP in Korean boys and the necessity for routine brain MRI examinations. This retrospective cross-sectional study ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Precocious puberty" returned 16 free, full-text review articles on human participants. First 3 results:

A Critical Appraisal of the Effect of Gonadotropin-Releasing Hormon Analog Treatment on Adult Height of Girls with Central Precocious Puberty.
 

Author(s): Abdullah Bereket

Journal: J Clin Res Pediatr Endocrinol. 2017 Dec;9(Suppl 2):33-48.

 

Central precocious puberty (CPP) is a diagnosis that pediatric endocrinologists worldwide increasingly make in girls of age 6-8 years and is mostly idiopathic. Part of the reason for increasing referral and diagnosis is the perception among the doctors as well as the patients that ...

Last Updated: 31 Dec 1969

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Central precocious puberty: revisiting the diagnosis and therapeutic management.
 

Author(s): Vinícius Nahime Brito, Angela Maria Spinola-Castro, Cristiane Kochi, Cristiane Kopacek, Paulo César Alves da Silva, Gil Guerra-Júnior

Journal: Arch Endocrinol Metab. 2016 Apr;60(2):163-72.

 

Clinical and laboratory diagnosis and treatment of central precocious puberty (CPP) remain challenging due to lack of standardization. The aim of this revision was to address the diagnostic and therapeutic features of CPP in Brazil based on relevant international literature and availability ...

Last Updated: 31 Dec 1969

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Treatment of Peripheral Precocious Puberty.
 

Author(s): Melissa Schoelwer, Erica A Eugster

Journal: Endocr Dev. 2016 ;29():230-9.

 

There are many etiologies of peripheral precocious puberty (PPP) with diverse manifestations resulting from exposure to androgens, estrogens, or both. The clinical presentation depends on the underlying process and may be acute or gradual. The primary goals of therapy are to halt ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Leuprorelin Acetate DPS (Leuplin DPS) Treatment Quarterly in Patients With Central Precocious Puberty
 

Status: Recruiting

Condition Summary: Central Precocious Puberty

 

Last Updated: 17 Oct 2017

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Analysis of Body Mass Index in Central Precocious Puberty Patients Treated With Leuprolide Acetate
 

Status: Recruiting

Condition Summary: Precocious Puberty, Central

 

Last Updated: 22 Nov 2016

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