Premenstrual dysphoric disorder

Common Name(s)

Premenstrual dysphoric disorder, PMDD

Premenstrual dysphoric disorder (PMDD) is a hormone-based mood disorder that affects around 2-8% of women in their reproductive years. PMDD is directly related to a woman’s menstrual cycle with symptoms that occur just before menstruation, or 7 to 10 days before a woman’s period and often lasting through the first few days of her period. Although it is not a hormonal disorder, the cycle of hormone changes associated with the female reproductive cycle play a role in PMDD. Women with a personal or family history of mood disorders and depression are considered to be more at risk for PMDD.

Psychological and behavioral symptoms include sadness or depression, tension, panic attacks, anger and irritability, difficulty focusing, tiredness, food cravings, and trouble sleeping. Physical symptoms include bloating, breast tenderness, headaches, and joint and muscle pain. Mood shifts are more extreme than PMS, and feelings of sadness and hopelessness, anxiety or tension, and irritability or anger are much more pronounced. Symptoms of PMDD have a greater impact on daily life than symptoms of PMS. PMDD symptoms usually begin in a woman’s 20s but may start earlier.

Diagnosing PMDD involves a review of your medical history and symptoms, a physical exam, an exam by your gynecologist or midwife, and further testing to rule out hormonal disorders. A psychiatric examination should also be completed to look at other factors leading to PMDD-like symptoms that might not be related to the menstrual cycle. Treatment for PMDD may include antidepressants, birth control, and changes in lifestyle and diet, including nutritional supplements. If you have been diagnosed with PPMD, talk to your gynecologist or midwife about the most current treatment options. Support groups are a good source of information and can connect you with other women who are living with PMDD.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Premenstrual dysphoric disorder" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Premenstrual dysphoric disorder" returned 66 free, full-text research articles on human participants. First 3 results:

The steroid metabolome in women with premenstrual dysphoric disorder during GnRH agonist-induced ovarian suppression: effects of estradiol and progesterone addback.
 

Author(s): T V Nguyen, J M Reuter, N W Gaikwad, D M Rotroff, H R Kucera, A Motsinger-Reif, C P Smith, L K Nieman, D R Rubinow, R Kaddurah-Daouk, P J Schmidt

Journal:

 

Clinical evidence suggests that symptoms in premenstrual dysphoric disorder (PMDD) reflect abnormal responsivity to ovarian steroids. This differential steroid sensitivity could be underpinned by abnormal processing of the steroid signal. We used a pharmacometabolomics approach in ...

Last Updated: 31 Dec 1969

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Prevalence, Severity, and Correlates of Premenstrual Dysphoric Disorder Symptoms Among Women in the Arabian Peninsula.
 

Author(s): Ossama T Osman, Sufyan Sabri, Taoufik Zoubeidi, Amal I Alharbi, Diaa Rizk, Hassib Narchi, Abdul-Kader Souid

Journal:

 

To study the prevalence of premenstrual dysphoric disorder (PMDD) symptom patterns among women in the United Arab Emirates and to measure the debilitating nature of PMDD symptoms and sociodemographic correlates.

Last Updated: 31 Dec 1969

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Epidemiological Distribution and Subtype Analysis of Premenstrual Dysphoric Disorder Syndromes and Symptoms Based on TCM Theories.
 

Author(s): Mingqi Qiao, Peng Sun, Haijun Wang, Yang Wang, Xianghong Zhan, Hongqi Liu, Xiaoyun Wang, Xia Li, Xiaoru Wang, Jibiao Wu, Fushun Wang

Journal: Biomed Res Int. 2017 ;2017():4595016.

 

We performed an epidemiological investigation of subjects with premenstrual dysphoric disorder (PMDD) to identify the clinical distribution of the major syndromes and symptoms. The pathogenesis of PMDD mainly involves the dysfunction of liver conveyance and dispersion. Excessive liver ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Premenstrual dysphoric disorder" returned 11 free, full-text review articles on human participants. First 3 results:

Premenstrual Syndrome and Premenstrual Dysphoric Disorder.
 

Author(s): Sabrina Hofmeister, Seth Bodden

Journal: Am Fam Physician. 2016 Aug;94(3):236-40.

 

Premenstrual disorders affect up to 12% of women. The subspecialties of psychiatry and gynecology have developed overlapping but distinct diagnoses that qualify as a premenstrual disorder; these include premenstrual syndrome and premenstrual dysphoric disorder. These conditions encompass ...

Last Updated: 31 Dec 1969

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Premenstrual Dysphoric Disorder: Epidemiology and Treatment.
 

Author(s): Liisa Hantsoo, C Neill Epperson

Journal: Curr Psychiatry Rep. 2015 Nov;17(11):87.

 

Recently designated as a disorder in the DSM-5, premenstrual dysphoric disorder (PMDD) presents an array of avenues for further research. PMDD's profile, characterized by cognitive-affective symptoms during the premenstruum, is unique from that of other affective disorders in its ...

Last Updated: 31 Dec 1969

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Effects and treatment methods of acupuncture and herbal medicine for premenstrual syndrome/premenstrual dysphoric disorder: systematic review.
 

Author(s): Su Hee Jang, Dong Il Kim, Min-Sun Choi

Journal:

 

During their reproductive years about 10% of women experience some kind of symptoms before menstruation (PMS) in a degree that affects their quality of life (QOL). Acupuncture and herbal medicine has been a recent favorable therapeutic approach. Thus we aimed to review the effects ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Alternative Treatments for Premenstrual Dysphoric Disorder
 

Status: Recruiting

Condition Summary: Premenstrual Dysphoric Disorder

 

Last Updated: 9 Jan 2018

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Single Session of tACS in a Depressive Episode
 

Status: Recruiting

Condition Summary: Depression; Major Depressive Disorder; Premenstrual Dysphoric Disorder; Depressive Episode

 

Last Updated: 7 Aug 2018

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