Primary open angle glaucoma

Common Name(s)

Primary open angle glaucoma

Primary open-angle glaucoma is a condition in which there is a blockage of fluid drainage from the eye. When fluid cannot drain properly from the eye, the pressure inside the eye may rise to a level that can damage the optic nerve. The optic nerve is the nerve that brings information from the back of the eye (retina), and damage to this nerve can result in vision loss and blindness.

Primary open-angle glaucoma is the most common form of glaucoma. It affects at least 3 million Americans. In primary open-angle glaucoma, fluid builds up in the anterior chamber of the eye because it cannot drain through a meshwork structure between the colored part of the eye that controls light entry (iris) and the lens of the eye (cornea). In primary open-angle glaucoma, the spacing between the iris and cornea is normal. The risk of developing primary open-angle glaucoma increases with age, especially above age 50, and is higher in those with a family history of this condition. Primary open-angle glaucoma can be asymptomatic or may have symptoms of decreased vision, particularly in the side or periphery, as well as pain, nausea, and headache.

Primary open-angle glaucoma can be diagnosed with a comprehensive dilated eye exam and by measuring intraocular pressure (IOP). Regular eye exams are important because this form of glaucoma is often asymptomatic prior to permanent vision loss. Treatment options include medication, laser surgery to create holes in the meshwork and allow fluid to drain from the anterior chamber (laser trabeculoplasty), and surgery to alter the iris to allow fluid drainage. If you have been diagnosed with primary open-angle glaucoma, talk to your doctor about the most current treatment options. Support groups are good sources of more information and can connect you with other people living with glaucoma.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Primary open angle glaucoma" for support, advocacy or research.

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The Glaucoma Foundation

The mission of The Glaucoma Foundation (TGF) is to fund groundbreaking research and to educate the public about the disease and the importance of early detection to prevent blindness.

Last Updated: 19 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Primary open angle glaucoma" for support, advocacy or research.

Logo
The Glaucoma Foundation

The mission of The Glaucoma Foundation (TGF) is to fund groundbreaking research and to educate the public about the disease and the importance of early detection to prevent blindness.

http://www.glaucomafoundation.org

Last Updated: 19 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Primary open angle glaucoma" returned 551 free, full-text research articles on human participants. First 3 results:

Association between glaucoma severity and driving cessation in subjects with primary open-angle glaucoma.
 

Author(s): Aya Takahashi, Kenya Yuki, Sachiko Awano-Tanabe, Takeshi Ono, Daisuke Shiba, Kazuo Tsubota

Journal:

 

The aim of this study, which included a baseline cross-sectional study and a 3-year follow-up prospective study, was to investigate the association between glaucomatous visual field damage and driving cessation in subjects with primary open-angle glaucoma (POAG).

Last Updated: 31 Dec 1969

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Uteroglobin and FLRG concentrations in aqueous humor are associated with age in primary open angle glaucoma patients.
 

Author(s): Esther L Ashworth Briggs, Tze'Yo Toh, Rajaraman Eri, Alex W Hewitt, Anthony L Cook

Journal:

 

The pathophysiological changes occurring in the trabecular meshwork in primary open angle glaucoma are poorly understood, but are thought to include increased extracellular matrix deposition, trabecular meshwork cell apoptosis, inflammation, trabecular meshwork calcification and altered ...

Last Updated: 31 Dec 1969

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The impact of primary open-angle glaucoma: Quality of life in Indian patients.
 

Author(s): Suresh Kumar, Parul Ichhpujani, Roopali Singh, Sahil Thakur, Madhu Sharma, Nimisha Nagpal

Journal: Indian J Ophthalmol. 2018 Mar;66(3):416-419.

 

Glaucoma significantly affects the quality of life (QoL) of a patient. Despite the huge number of glaucoma patients in India, not many, QoL studies have been carried out. The purpose of the present study was to evaluate the QoL in Indian patients with varying severity of glaucoma.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Primary open angle glaucoma" returned 33 free, full-text review articles on human participants. First 3 results:

Migraine as a risk factor for primary open angle glaucoma: A systematic review and meta-analysis.
 

Author(s): Chang Xu, Jingjing Li, Zhi Li, Xiaochun Mao

Journal: Medicine (Baltimore). 2018 Jul;97(28):e11377.

 

Migraine is increasingly being reported as a risk factor for primary open angle glaucoma (POAG). However, studies aimed to investigate this association yielded conflicting results. To assess the consistency of the data on the topic, we performed a systematic review and meta-analysis. ...

Last Updated: 31 Dec 1969

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Evidence-based practice guideline of Chinese herbal medicine for primary open-angle glaucoma (qingfeng -neizhang).
 

Author(s): Yingxin Yang, Qiu-Yan Ma, Yue Yang, Yu-Peng He, Chao-Ting Ma, Qiang Li, Ming Jin, Wei Chen

Journal: Medicine (Baltimore). 2018 Mar;97(13):e0126.

 

Primary open angle glaucoma (POAG) is a chronic, progressive optic neuropathy. The aim was to develop an evidence-based clinical practice guideline of Chinese herbal medicine (CHM) for POAG with focus on Chinese medicine pattern differentiation and treatment as well as approved herbal ...

Last Updated: 31 Dec 1969

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Simplifying "target" intraocular pressure for different stages of primary open-angle glaucoma and primary angle-closure glaucoma.
 

Author(s): Ramanjit Sihota, Dewang Angmo, Deepa Ramaswamy, Tanuj Dada

Journal: Indian J Ophthalmol. 2018 04;66(4):495-505.

 

Lowering of intraocular pressure is currently the only therapeutic measure for Glaucoma management. Many longterm, randomized trials have shown the efficacy of lowering IOP, either by a percentage of baseline, or to a specified level. This has lead to the concept of 'Target" IOP, ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

PRO-122 Versus Concomitant Therapy in Subjects With Uncontrolled Primary Open-angle Glaucoma (PRO-122LATAM)
 

Status: Recruiting

Condition Summary: Primary Open-angle Glaucoma

 

Last Updated: 6 Feb 2018

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Modified Trabeculectomy With an ESST Versus Conventional SST for Management of Primary Open Angle Glaucoma
 

Status: Not yet recruiting

Condition Summary: Primary Open-angle Glaucoma

 

Last Updated: 27 Mar 2018

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Study of SHP639 Eye Drops in Adults With High Eye Pressure or Primary Open-angle Glaucoma
 

Status: Recruiting

Condition Summary: Primary Open-angle Glaucoma (POAG); Ocular Hypertension

 

Last Updated: 20 Jul 2018

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