Proopiomelanocortin deficiency

Common Name(s)

Proopiomelanocortin deficiency

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Proopiomelanocortin deficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Proopiomelanocortin deficiency" returned 1 free, full-text research articles on human participants. First 3 results:

Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
 

Author(s): Peter Kühnen, Karine Clément, Susanna Wiegand, Oliver Blankenstein, Keith Gottesdiener, Lea L Martini, Knut Mai, Ulrike Blume-Peytavi, Annette Grüters, Heiko Krude

Journal: N. Engl. J. Med.. 2016 Jul;375(3):240-6.

 

Patients with rare defects in the gene encoding proopiomelanocortin (POMC) have extreme early-onset obesity, hyperphagia, hypopigmentation, and hypocortisolism, resulting from the lack of the proopiomelanocortin-derived peptides melanocyte-stimulating hormone and corticotropin. In ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Proopiomelanocortin deficiency" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Setmelanotide for the Treatment of Early-Onset POMC Deficiency Obesity
 

Status: Recruiting

Condition Summary: Pro-opiomelanocortin (POMC) Deficiency Obesity

 

Last Updated: 13 Jul 2017

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Setmelanotide Phase 2 Treatment Trial in Patients With Rare Genetic Disorders of Obesity
 

Status: Recruiting

Condition Summary: Pro-opiomelanocortin (POMC) Deficiency Obesity (Heterozygous or Epigenetic); Leptin Receptor Deficiency Obesity; Bardet-Biedl Syndrome; Alstrom Syndrome

 

Last Updated: 10 Aug 2017

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RM-493 Treatment Trial in Proopiomelanocortin (POMC) Deficient Patients
 

Status: Recruiting

Condition Summary: Homozygous or Compound Heterozygous POMC, LEPR or PCSK1 Gene Mutation

 

Last Updated: 19 Feb 2016

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