Psoriasis

Common Name(s)

Psoriasis

Psoriasis is a chronic (long-lasting) skin condition that causes cells to grow too quickly and results in red, scaly, and occasionally itchy patches on the skin. In normal skin, cells flake off from the surface and are replaced by new cells every four weeks. In people with psoriasis, new cells form and quickly move to the surface of the skin, forming thick patches (plaques) that typically appear on the elbows, knees, scalp, lower back, hands, or feet. These patches are usually dry and itchy. If scraped or picked, they can also bleed. In some cases of psoriasis, the areas where bones meet (joints) may also become swollen and stiff, which is called psoriatic arthritis. Psoriasis can be mild, causing small areas of rash, or severe, causing large areas of raised, red and loose plaques. Symptoms of psoriasis tend to come and go. Risk factors that can lead to the return of symptoms (flare-ups) include a dry climate, infections, stress, dry skin and certain medications.

The exact cause of psoriasis is unknown. However, it is thought to be an autoimmune disease, which means something causes the body’s immune system to attack itself, mistaking healthy cells for something foreign (from outside the body). It is believed that both genetic and environmental factors play a role in psoriasis. In order to diagnose psoriasis, your doctor will gather a medical history and perform a physical exam that focuses on the skin. Your doctor may also remove and examine a small piece of the affected skin (skin biopsy). There is no cure for psoriasis. However, there are many treatment options that may help control the symptoms. These include creams that can be applied to the surface of the skin (topical), oral medications, moisturizers, and light therapy. If you or your child have been diagnosed with psoriasis, talk with your doctor to decide which treatment option is best for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Psoriasis" for support, advocacy or research.

National Psoriasis Foundation

Our mission is to find a cure for psoriasis and psoriatic arthritis and to eliminate their devastating effects through research, advocacy and education.

Last Updated: 26 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Psoriasis" for support, advocacy or research.

National Psoriasis Foundation

Our mission is to find a cure for psoriasis and psoriatic arthritis and to eliminate their devastating effects through research, advocacy and education.

http://www.psoriasis.org/

Last Updated: 26 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
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General Resources

For scientists and medical professionals

Information about how to apply for National Psoriasis Foundation research grants and fellowships, our medical journal and other science-related materials for medical professionals.

Updated 15 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Psoriasis" returned 2511 free, full-text research articles on human participants. First 3 results:

Psoriasis & cardiovascular morbidity: The missing links?
 

Author(s): Satyaki Ganguly, Lopamudra Ray

Journal: Indian J. Med. Res.. 2017 12;146(6):677-679.

 

Last Updated: 31 Dec 1969

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The potential role of Th17 lymphocytes in patients with psoriasis.
 

Author(s): Mahnaz Mansouri, Parvine Mansouri, Abbas Ali Raze, Zohreh Jadali

Journal: An Bras Dermatol. ;93(1):63-66.

 

Psoriasis is a chronic inflammatory disorder, characterized by increased keratinocyte proliferation due to abnormal differentiation of basal keratinocytes. The etiology of the disease is unclear, and according to the survey results, it is hypothesized that a combination of genetic ...

Last Updated: 31 Dec 1969

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Pivotal role of Acitretin nanovesicular gel for effective treatment of psoriasis: ex vivo-in vivo evaluation study.
 

Author(s): Irhan Ibrahim Abu Hashim, Noha Fawzy Abo El-Magd, Ahmed Ramadan El-Sheakh, Mohammed Fawzy Hamed, Abd El-Gawad Helmy Abd El-Gawad

Journal:

 

The goal of the current study was to explore the potential benefits of Acitretin (Act) nanovesicular gel as a prospective antipsoriatic topical delivery system counteracting the drug challenges in terms of its extremely low aqueous solubility, instability, skin irritation, and serious ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Psoriasis" returned 422 free, full-text review articles on human participants. First 3 results:

The differential impact of scientific quality, bibliometric factors, and social media activity on the influence of systematic reviews and meta-analyses about psoriasis.
 

Author(s): Juan Ruano, Macarena Aguilar-Luque, Francisco Gómez-Garcia, Patricia Alcalde Mellado, Jesus Gay-Mimbrera, Pedro J Carmona-Fernandez, Beatriz Maestre-López, Juan Luís Sanz-Cabanillas, José Luís Hernández Romero, Marcelino González-Padilla, Antonio Vélez García-Nieto, Beatriz Isla-Tejera

Journal:

 

Researchers are increasingly using on line social networks to promote their work. Some authors have suggested that measuring social media activity can predict the impact of a primary study (i.e., whether or not an article will be highly cited). However, the influence of variables ...

Last Updated: 31 Dec 1969

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How relevant are vascular endothelial growth factor and intercellular adhesion molecule in the systemic capillary leak syndrome of psoriasis?
 

Author(s): Aline Lopes Bressan, Daniele Pereira, Paula Mota Medeiros, Sueli Carneiro, Luna Azulay-Abulafia

Journal: An Bras Dermatol. ;92(6):826-829.

 

Psoriasis is a chronic disease, characterized by erythematous scaly lesions, presented in eight different forms: plaques, guttate, pustular, erythrodermic, inverse, nail and scalp psoriasis, and psoriatic arthritis. Its development depends on genetic factors, external stimulus and ...

Last Updated: 31 Dec 1969

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Biologicals and small molecules in psoriasis: A systematic review of economic evaluations.
 

Author(s): Christian Kromer, Daniel Celis, Diana Sonntag, Wiebke K Peitsch

Journal:

 

Biological therapy for moderate-to-severe psoriasis is highly effective but cost-intensive. This systematic review aimed at analyzing evidence on the cost-effectiveness of biological treatment of moderate-to-severe psoriasis. A literature search was conducted until 30/06/2017 in PubMed, ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Risankizumab Therapy Versus Placebo for Subjects With Psoriasis in the Russian Federation
 

Status: Not yet recruiting

Condition Summary: Psoriasis

 

Last Updated: 4 May 2018

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Risankizumab Versus Secukinumab for Subjects With Moderate to Severe Plaque Psoriasis
 

Status: Not yet recruiting

Condition Summary: Psoriasis

 

Last Updated: 23 Mar 2018

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The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis
 

Status: Recruiting

Condition Summary: Psoriasis

 

Last Updated: 4 Dec 2017

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