Psoriasis

Common Name(s)

Psoriasis

Psoriasis is a chronic (long-lasting) skin condition that causes cells to grow too quickly and results in red, scaly, and occasionally itchy patches on the skin. In normal skin, cells flake off from the surface and are replaced by new cells every four weeks. In people with psoriasis, new cells form and quickly move to the surface of the skin, forming thick patches (plaques) that typically appear on the elbows, knees, scalp, lower back, hands, or feet. These patches are usually dry and itchy. If scraped or picked, they can also bleed. In some cases of psoriasis, the areas where bones meet (joints) may also become swollen and stiff, which is called psoriatic arthritis. Psoriasis can be mild, causing small areas of rash, or severe, causing large areas of raised, red and loose plaques. Symptoms of psoriasis tend to come and go. Risk factors that can lead to the return of symptoms (flare-ups) include a dry climate, infections, stress, dry skin and certain medications.

The exact cause of psoriasis is unknown. However, it is thought to be an autoimmune disease, which means something causes the body’s immune system to attack itself, mistaking healthy cells for something foreign (from outside the body). It is believed that both genetic and environmental factors play a role in psoriasis. In order to diagnose psoriasis, your doctor will gather a medical history and perform a physical exam that focuses on the skin. Your doctor may also remove and examine a small piece of the affected skin (skin biopsy). There is no cure for psoriasis. However, there are many treatment options that may help control the symptoms. These include creams that can be applied to the surface of the skin (topical), oral medications, moisturizers, and light therapy. If you or your child have been diagnosed with psoriasis, talk with your doctor to decide which treatment option is best for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Psoriasis" for support, advocacy or research.

National Psoriasis Foundation

Our mission is to find a cure for psoriasis and psoriatic arthritis and to eliminate their devastating effects through research, advocacy and education.

Last Updated: 26 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Psoriasis" for support, advocacy or research.

National Psoriasis Foundation

Our mission is to find a cure for psoriasis and psoriatic arthritis and to eliminate their devastating effects through research, advocacy and education.

http://www.psoriasis.org/

Last Updated: 26 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

General Resources

For scientists and medical professionals

Information about how to apply for National Psoriasis Foundation research grants and fellowships, our medical journal and other science-related materials for medical professionals.

Updated 15 Nov 2012

Go To URL
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Psoriasis" returned 2593 free, full-text research articles on human participants. First 3 results:

Association between physical activity and risk of prevalent psoriasis: A MOOSE-compliant meta-analysis.
 

Author(s): Qi Zheng, Xiao Ying Sun, Xiao Miao, Rong Xu, Tian Ma, Ya Nan Zhang, Hong Jin Li, Bin Li, Xin Li

Journal: Medicine (Baltimore). 2018 Jul;97(27):e11394.

 

Psoriasis is a common chronic relapsing immune-mediated inflammatory disease, whose prevalence has increased in recent years. Some physicians believe that physical activity is associated with numerous health-related benefits in adults with dermatoses. While numerous studies have suggested ...

Last Updated: 31 Dec 1969

Go To URL
Density of mast cells and intensity of pruritus in psoriasis vulgaris: a cross sectional study.
 

Author(s): Letícia Pargendler Peres, Fabiana Bazanella Oliveira, André Cartell, Nicolle Gollo Mazzotti, Tania Ferreira Cestari

Journal: An Bras Dermatol. 2018 Jun;93(3):368-372.

 

Psoriasis is a chronic and prevalent disease, and the associated pruritus is a common, difficult-to-control symptom. The mediators involved in psoriatic pruritus have not been fully established.

Last Updated: 31 Dec 1969

Go To URL
Tazarotene gel with narrow-band UVB phototherapy: a synergistic combination in psoriasis.
 

Author(s): Surabhi Dayal, Rajiv Kaura, Priyadarshini Sahu, Vijay Kumar Jain

Journal: An Bras Dermatol. 2018 Jun;93(3):385-390.

 

Narrow-band UVB (NB-UVB) has been shown to be one of the most effective treatment modalities for psoriasis. Tazarotene, a known effective anti-psoriatic modality, when combined with NB-UVB may enhance the therapeutic success.

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Psoriasis" returned 451 free, full-text review articles on human participants. First 3 results:

Role of the IL-23/IL-17 Axis in Psoriasis and Psoriatic Arthritis: The Clinical Importance of Its Divergence in Skin and Joints.
 

Author(s): Marie-Astrid Boutet, Alessandra Nerviani, Gabriele Gallo Afflitto, Costantino Pitzalis

Journal:

 

Psoriasis is a chronic systemic inflammatory disease causing erythematosus and scaly skin plaques; up to 30% of patients with psoriasis develop Psoriatic Arthritis (PsA), which is characterised by inflammation and progressive damage of the peripheral joints and/or the spine and/or ...

Last Updated: 31 Dec 1969

Go To URL
The differential impact of scientific quality, bibliometric factors, and social media activity on the influence of systematic reviews and meta-analyses about psoriasis.
 

Author(s): Juan Ruano, Macarena Aguilar-Luque, Francisco Gómez-Garcia, Patricia Alcalde Mellado, Jesus Gay-Mimbrera, Pedro J Carmona-Fernandez, Beatriz Maestre-López, Juan Luís Sanz-Cabanillas, José Luís Hernández Romero, Marcelino González-Padilla, Antonio Vélez García-Nieto, Beatriz Isla-Tejera

Journal:

 

Researchers are increasingly using on line social networks to promote their work. Some authors have suggested that measuring social media activity can predict the impact of a primary study (i.e., whether or not an article will be highly cited). However, the influence of variables ...

Last Updated: 31 Dec 1969

Go To URL
How relevant are vascular endothelial growth factor and intercellular adhesion molecule in the systemic capillary leak syndrome of psoriasis?
 

Author(s): Aline Lopes Bressan, Daniele Pereira, Paula Mota Medeiros, Sueli Carneiro, Luna Azulay-Abulafia

Journal: An Bras Dermatol. ;92(6):826-829.

 

Psoriasis is a chronic disease, characterized by erythematous scaly lesions, presented in eight different forms: plaques, guttate, pustular, erythrodermic, inverse, nail and scalp psoriasis, and psoriatic arthritis. Its development depends on genetic factors, external stimulus and ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 25 Jul 2018

Go to URL

Last Updated: 31 Jul 2018

Go to URL
The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis
 

Status: Recruiting

Condition Summary: Psoriasis

 

Last Updated: 12 Jun 2018

Go to URL