Heartburn

Common Name(s)

Heartburn, Pyrosis

Heartburn (pyrosis) is a common condition. Occasional heartburn is not a cause for concern. However, heartburn which occurs often can be a symptom of gastric reflux. Left untreated, gastric reflux can lead to gastroesophageal reflux disease (GERD). In addition, sometimes what seems to be heartburn is a sign of a heart attack, so if the chest pain is severe or you are also experiencing shortness of breath, pain in the arm or jaw or any other symptom of a heart attack, seek medical attention immediately.

The major symptom of heartburn is a burning feeling in chest most often after eating or late at night. The pain tends to get worse when you lie down or bend over. It usually starts in chest and spreads to the neck, throat, or jaw. Heartburn is caused when stomach acid backs up into your esophagus (the tube that carries food from your mouth to you to your stomach. Most commonly the muscle which is supposed to stop this from happening (lower esophageal sphincter) weakens or relaxes when it shouldn’t.

Almost half the population will has heartburn at one point in their life. However, some foods and drinks seem more likely to trigger heartburn for most people. These include spicy foods, citrus, alcohol, carbonated drinks, coffee, and large amounts of fatty foods. Being overweight or pregnant or overeating may also increase your risk of developing heartburn. .

Diagnosis may include an X-ray, endoscopy, ambulatory acid probe tests, and esophageal motility tests. Antacids can be used to treat mild heartburn. If your heartburn continues, your doctor may prescribe different medication. If you have frequent symptoms of heartburn, talk to your doctor about the most current treatment options. If your diagnosis includes GERD, support groups can be a good resource of information and can help connect you with others living with GERD.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heartburn" for support, advocacy or research.

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heartburn" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Heartburn" returned 128 free, full-text research articles on human participants. First 3 results:

Dexlansoprazole for Heartburn Relief in Adolescents with Symptomatic, Nonerosive Gastro-esophageal Reflux Disease.
 

Author(s): Benjamin D Gold, Betsy Pilmer, Jaroslaw Kierkuś, Barbara Hunt, Maria Claudia Perez, David Gremse

Journal: Dig. Dis. Sci.. 2017 Nov;62(11):3059-3068.

 

Proton pump inhibitors are commonly used to treat gastro-esophageal reflux disease (GERD) and nonerosive GERD (NERD) in adolescents and adults. Despite the efficacy of available medications, many patients have persisting symptoms, indicating a need for more effective agents.

Last Updated: 16 Sep 2017

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Ambulatory 24-hour multichannel intraluminal impedance-pH monitoring and high resolution endoscopy distinguish patients with non-erosive reflux disease from those with functional heartburn.
 

Author(s): Chuanlian Chu, Quanlin Du, Changqing Li, Linlu Zhang, Xiaoyan Zhou, Fang Zuo, Yanmin Zhang, Fang Li, Guofeng Xie, Yanqing Li

Journal:

 

To assess the contribution of 24-h esophageal multichannel intraluminal impedance and pH (MII-pH) monitoring and high resolution endoscopy (HRE) with i-scan imaging in differentiating non erosive reflux disease (NERD) from functional heartburn (FH).

Last Updated: 6 Apr 2017

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Prevalence of dyspeptic symptoms and heartburn of adults in Belo Horizonte, Brazil.
 

Author(s): Alessandra Maciel Almeida, Luísa Alvarenga Guerra Martins, Patrícia Liz Terenzi Cunha, Viviane Willig Brasil, Lucas Galuppo Fernandes Félix, Maria do Carmo Friche Passos

Journal: Arq Gastroenterol. ;54(1):46-50.

 

- Medical literature has shown dyspepsia and heartburn-related symptoms occur among 15% to 40% of the population. These symptoms can occur at any age and are more prevalent in women.

Last Updated: 12 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Heartburn" returned 15 free, full-text review articles on human participants. First 3 results:

A Hispanic female patient with heartburn: A rare presentation of Paroxysmal Nocturnal Hemoglobinuria.
 

Author(s): Luis A Figueroa-Jiménez, Amy Lee González-Márquez, Ricardo Alicea-Guevara, Mónica Santiago-Casiano, Maryknoll de la Paz-López, Luis Negrón-Garcia, Luis Báez-Diaz, William Cáceres-Pérkins

Journal: Bol Asoc Med P R. ;107(3):9-12.

 

Paroxysmal nocturnal hemoglobinuria (PNH) is a non-malignant, acquired clonal hematopoietic stem cell disease that can present with bone marrow failure, hemolytic anemia, smooth muscle dystonias, and thrombosis. We present a case of a 32 year-old-female, G2P2A0 with no past medical ...

Last Updated: 8 Jan 2016

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Overlap of functional heartburn and gastroesophageal reflux disease with irritable bowel syndrome.
 

Author(s): Nicola de Bortoli, Irene Martinucci, Massimo Bellini, Edoardo Savarino, Vincenzo Savarino, Corrado Blandizzi, Santino Marchi

Journal: World J. Gastroenterol.. 2013 Sep;19(35):5787-97.

 

Several studies indicate a significant degree of overlap between irritable bowel syndrome (IBS) and gastroesophageal reflux disease (GERD). Likewise, both functional heartburn (FH) and IBS are functional digestive disorders that may occur in the same patients. However, data establishing ...

Last Updated: 14 Oct 2013

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Constipation, haemorrhoids, and heartburn in pregnancy.
 

Author(s): Juan C Vazquez

Journal:

 

Constipation, heartburn, and haemorrhoids are common gastrointestinal complaints during pregnancy. Constipation occurs in 11% to 38% of pregnant women. Although the exact prevalence of haemorrhoids during pregnancy is unknown, the condition is common, and the prevalence of symptomatic ...

Last Updated: 22 Mar 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Efficacy and Safety of Dexlansoprazole on Heartburn Relief in Chinese Patients
 

Status: Recruiting

Condition Summary: Heartburn; Gastroesophageal Reflux Disease

 

Last Updated: 1 Jun 2017

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Last Updated: 3 Dec 2015

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Efficacy Study of Articaine Lozenge to Enhance the Procedural Compliance of the Adults Undergoing Gastroduodenoscopy
 

Status: Recruiting

Condition Summary: Dyspepsia; Hematemesis; Abdominal Pain; Heartburn

 

Last Updated: 29 Oct 2017

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