Renal glycosuria

Common Name(s)

Renal glycosuria

Renal glycosuria is a rare condition in which the simple sugar glucose is excreted in the urine despite normal or low blood glucose levels. With normal kidney function, glucose is excreted in the urine only when there are abnormally elevated levels of glucose in the blood. However, in those with renal glycosuria, glucose is abnormally eliminated in the urine due to improper functioning of the renal tubules, which are the primary components of the filtering units of the kidneys. In most affected individuals, the condition causes no apparent symptoms or serious effects. When renal glycosuria occurs as an isolated finding with otherwise normal kidney function, the condition is thought to be inherited as an autosomal recessive trait.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Renal glycosuria" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Renal glycosuria" returned 8 free, full-text research articles on human participants. First 3 results:

Influence of Familial Renal Glycosuria Due to Mutations in the SLC5A2 Gene on Changes in Glucose Tolerance over Time.
 

Author(s): Emilia Ottosson-Laakso, Tiinamaija Tuomi, Björn Forsén, Monika Gullström, Per-Henrik Groop, Leif Groop, Petter Vikman

Journal:

 

Familial renal glycosuria is an inherited disorder resulting in glucose excretion in the urine despite normal blood glucose concentrations. It is most commonly due to mutations in the SLC5A2 gene coding for the glucose transporter SGLT2 in the proximal tubule. Several drugs have been ...

Last Updated: 7 Jan 2016

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SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria.
 

Author(s): Yukihiro Chino, Yoshishige Samukawa, Soichi Sakai, Yasuhiro Nakai, Jun-ichi Yamaguchi, Takeo Nakanishi, Ikumi Tamai

Journal: Biopharm Drug Dispos. 2014 Oct;35(7):391-404.

 

Sodium glucose cotransporter 2 (SGLT2) inhibitors have been reported to lower the serum uric acid (SUA) level. To elucidate the mechanism responsible for this reduction, SUA and the urinary excretion rate of uric acid (UE(UA)) were analysed after the oral administration of luseogliflozin, ...

Last Updated: 8 Oct 2014

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[Renal glycosuria: report of two cases].
 

Author(s): Joana Chaves Rebelo, Felisbela Rocha, Susana Gama de Sousa, Paulo Teixeira

Journal: J Bras Nefrol. ;34(3):291-2.

 

Glycosuria as an accidental finding implies a diagnostic workout. We present the cases of two asymptomatic female teenagers referred to a hospital outpatient clinic due to isolated glycosuria detected in a routine analysis. The diagnostic workout revealed isolated glycosuria in the ...

Last Updated: 26 Oct 2012

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Reviews from the PubMed Database

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The terms "Renal glycosuria" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

PROTOCOL 3: Role of the Renal Nerves in the Increase in EGP in Response to Glucosuria
 

Status: Recruiting

Condition Summary: Diabetes Mellitus, Type 2

 

Last Updated: 24 May 2017

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