Retinal degeneration

Common Name(s)

Retinal degeneration

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Retinal degeneration" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Retinal degeneration" returned 344 free, full-text research articles on human participants. First 3 results:

Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration.
 

Author(s): Michiko Mandai, Yasuo Kurimoto, Masayo Takahashi

Journal: N. Engl. J. Med.. 2017 08;377(8):792-793.

 

Last Updated: 23 Aug 2017

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Activated Retinal Pigment Epithelium, an Optical Coherence Tomography Biomarker for Progression in Age-Related Macular Degeneration.
 

Author(s): Christine A Curcio, Emma C Zanzottera, Thomas Ach, Chandrakumar Balaratnasingam, K Bailey Freund

Journal: Invest. Ophthalmol. Vis. Sci.. 2017 May;58(6):BIO211-BIO226.

 

To summarize and contextualize recent histology and clinical imaging publications on retinal pigment epithelium (RPE) fate in advanced age-related macular degeneration (AMD); to support RPE activation and migration as important precursors to atrophy, manifest as intraretinal hyperreflective ...

Last Updated: 8 Aug 2017

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Detailed Clinical Phenotype and Molecular Genetic Findings in CLN3-Associated Isolated Retinal Degeneration.
 

Author(s): Cristy A Ku, Sarah Hull, Gavin Arno, Ajoy Vincent, Keren Carss, Robert Kayton, Douglas Weeks, Glenn W Anderson, Ryan Geraets, Camille Parker, David A Pearce, Michel Michaelides, Robert E MacLaren, Anthony G Robson, Graham E Holder, Elise Heon, F Lucy Raymond, Anthony T Moore, Andrew R Webster, Mark E Pennesi

Journal: JAMA Ophthalmol. 2017 Jul;135(7):749-760.

 

Mutations in genes traditionally associated with syndromic retinal disease are increasingly found to cause nonsyndromic inherited retinal degenerations. Mutations in CLN3 are classically associated with juvenile neuronal ceroid lipofuscinosis, a rare neurodegenerative disease with ...

Last Updated: 25 May 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Retinal degeneration" returned 46 free, full-text review articles on human participants. First 3 results:

Neuroprotective Strategy in Retinal Degeneration: Suppressing ER Stress-Induced Cell Death via Inhibition of the mTOR Signal.
 

Author(s): Bin Fan, Ying-Jian Sun, Shu-Yan Liu, Lin Che, Guang-Yu Li

Journal:

 

The retina is a specialized sensory organ, which is essential for light detection and visual formation in the human eye. Inherited retinal degenerations are a heterogeneous group of eye diseases that can eventually cause permanent vision loss. UPR (unfolded protein response) and ER ...

Last Updated: 20 Jan 2017

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Retinal degeneration following lead exposure - functional aspects.
 

Author(s): Andrzej Sobieniecki, Izabela Gutowska, Anna MachaliƄska, Dariusz Chlubek, Irena Baranowska-Bosiacka

Journal:

 

Due to the prevalence of lead (Pb) in the environment, the neurotoxic effects on the human body have become an important clinical problem. Despite that Pb concentration in the environment decreased after banning its use in petrol, it is still a significant issue which can affect child ...

Last Updated: 16 Dec 2015

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Therapeutic Approaches to Histone Reprogramming in Retinal Degeneration.
 

Author(s): Andre K Berner, Mark E Kleinman

Journal: Adv. Exp. Med. Biol.. 2016 ;854():39-44.

 

Recent data have revealed epigenetic derangements and subsequent chromatin remodeling as a potent biologic switch for chronic inflammation and cell survival which are important therapeutic targets in the pathogenesis of several retinal degenerations. Histone deacetylases (HDACs) are ...

Last Updated: 2 Oct 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Quality of Life Measures in Patients With Retinal Degeneration
 

Status: Recruiting

Condition Summary: Retinal Degeneration

 

Last Updated: 12 Jul 2016

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Natural History of Eye Diseases Related to ABCA4 Mutations
 

Status: Recruiting

Condition Summary: Retinal Degeneration; ABCA4-Related Retinopathies

 

Last Updated: 12 Sep 2017

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Stem Cell Therapy for Outer Retinal Degenerations
 

Status: Recruiting

Condition Summary: Age Related Macular Degeneration; Stargardt's Disease; Exudative Age-related Macular Degeneration

 

Last Updated: 8 Aug 2017

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