Rheumatoid arthritis

Common Name(s)

Rheumatoid arthritis

Rheumatoid arthritis is a chronic inflammatory disorder that normally affects the small joints in your hands and feet. It is an autoimmune disease meaning your body’s immune system, which protects your health by attacking foreign substances such as bacteria and viruses, mistakenly attacks your joints causing inflammation or swelling, redness, warmth and pain. The severity of symptoms varies between individuals and may come and go. Symptoms may include tender, warm, and swollen joints, joint stiffness especially in the morning, firm bumps of tissue under the skin on your arms (rheumatoid nodules), fatigue, fever, and weight loss. Symptoms may get progressively worse and may affect your wrist, knee, ankle, elbow, hip and shoulder joints.

The reason the immune system attacks the joints is unknown, but doctors believe there is a genetic component along with environmental factors. Individuals with a family history, between the ages of 40 and 60, and female are at a higher risk of rheumatoid arthritis. Rheumatoid arthritis may increase your risk of developing osteoporosis, carpal tunnel syndrome, heart problems, and lung disease.

Rheumatoid arthritis can be difficult to diagnose in the beginning because there is no single blood test or physical finding to confirm the diagnosis. However, your doctor may perform a physical exam to check your joints, blood tests, and an x-rays to help diagnose. While there is currently no cure for rheumatoid arthritis, there are medications to ease the symptoms, reduce inflammation, and slow down the progression of the disease. If you or a family member has been diagnosed with rheumatoid arthritis, talk with your doctor to learn about the most current treatment options. Support groups are also good sources of information and support.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Rheumatoid arthritis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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International Foundation for Autoimmune Arthritis

We are committed to eliminating the adversity caused by autoimmune arthritis by uniting resources that will raise global awareness, providing wellness education and support, and conducting patient-centered research that will improve the quality of life for those affected by these diseases.

Last Updated: 18 Sep 2014

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US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

Last Updated: 24 Sep 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Rheumatoid arthritis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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International Foundation for Autoimmune Arthritis

We are committed to eliminating the adversity caused by autoimmune arthritis by uniting resources that will raise global awareness, providing wellness education and support, and conducting patient-centered research that will improve the quality of life for those affected by these diseases.

http://www.ifautoimmunearthritis.org

Last Updated: 18 Sep 2014

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US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

http://www.uspainfoundation.org

Last Updated: 24 Sep 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Rheumatoid arthritis" returned 10594 free, full-text research articles on human participants. First 3 results:

Multiple extra-articular synovial cysts accompanied by rheumatoid arthritis in the bilateral elbow joints: A case report.
 

Author(s): Jingfeng Zhang, Junli Wang, Xiongwei Mao, Zhengang Li

Journal: Medicine (Baltimore). 2018 Feb;97(7):e9879.

 

Synovial cysts are well known in rheumatoid arthritis (RA), and most common in the popliteal fossa. They may produce lots of local symptoms and complaints, which may present initially as an unrelated clinical condition. Few studies have reported multiple extra-articular synovial cysts ...

Last Updated: 31 Dec 1969

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Course of hepatitis E infection in a patient with rheumatoid arthritis and autoimmune hepatitis: A case report.
 

Author(s): Victoria Thodou, Matthias Buechter, Paul Manka, Guido Gerken, Alisan Kahraman

Journal: Medicine (Baltimore). 2017 Dec;96(51):e9407.

 

A 62-year-old male patient was admitted to our clinic in February 2016 with persistently elevated liver enzymes.

Last Updated: 31 Dec 1969

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Xanthomatosis in bilateral hands mimicking rheumatoid arthritis: A case report.
 

Author(s): Dan Li, Longfei You, Songqing Fan, Lihua Tan

Journal: Medicine (Baltimore). 2017 Dec;96(51):e9399.

 

Xanthomatosis often accompanies familial hypercholesterolemia. This disease usually occurs in tendons, most commonly located in the Achilles tendon; occasionally it can also be seen in other systems. Although there are previous reports for bilateral hand extensor tendon involvement, ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Rheumatoid arthritis" returned 1193 free, full-text review articles on human participants. First 3 results:

Role of extracellular vesicles in rheumatoid arthritis.
 

Author(s): Haitao Fu, Die Hu, Licheng Zhang, Peifu Tang

Journal: Mol. Immunol.. 2018 Jan;93():125-132.

 

Cell-derived extracellular vesicles (EVs) are involved in the pathogenesis of rheumatoid arthritis (RA), playing important roles in antigen presentation, inflammation, angiogenesis, cell-cell signal communication, thrombosis, and articular cartilage extracellular matrix degradation. ...

Last Updated: 31 Dec 1969

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Pain and other self-report scores in patients with osteoarthritis indicate generally similar disease burden to patients with rheumatoid arthritis.
 

Author(s): Jacquelin R Chua, Kathryn A Gibson, Theodore Pincus

Journal: Clin. Exp. Rheumatol.. ;35 Suppl 107(5):88-93.

 

Osteoarthritis (OA) is regarded as a less severe form of arthritis than rheumatoid arthritis (RA) by health professionals and the general public, based largely on laboratory findings of autoantibodies and acute phase reactants. Relatively few studies have reported data from the patient's ...

Last Updated: 31 Dec 1969

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Pain mechanisms in rheumatoid arthritis.
 

Author(s): Daniel F McWilliams, David A Walsh

Journal: Clin. Exp. Rheumatol.. ;35 Suppl 107(5):94-101.

 

Understanding of the causes and underlying mechanisms of pain in people with RA is rapidly changing. With the advent of more effective disease modifying drugs, joint inflammation is becoming a more treatable cause of pain, and joint damage can often be prevented. However, the long-term ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

INCMNSZ - Rheumatoid Arthritis Cohort
 

Status: Recruiting

Condition Summary: Early Rheumatoid Arthritis; Rheumatoid Arthritis

 

Last Updated: 9 Jan 2018

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Discovering the Antecedents of Rheumatoid Arthritis Flare
 

Status: Recruiting

Condition Summary: Rheumatoid Arthritis

 

Last Updated: 18 Oct 2017

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Rheumatoid Arthritis Patients and Porphyromonas Gingivalis
 

Status: Recruiting

Condition Summary: Rheumatoid Arthritis

 

Last Updated: 12 Jan 2017

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