Salmonella infection

Common Name(s)

Salmonella infection

Salmonella infection is a relatively common bacterial infection that typically affects the intestinal tract. Some people with salmonella infection have no symptoms while others may have diarrhea, fever, and abdominal cramps. Other symptoms include nausea, vomiting, headaches, and blood in the stool. If a person has symptoms from a salmonella infection, they typically start between 8 and 72 hours and last between 4 and 7 days. A salmonella infection is usually not life threatening, but it can be dangerous for individuals with weakened immune systems, including children, the elderly, and pregnant women. Some people with a salmonella infection can get severe diarrhea that may need urgent medical treatment. In some cases, the salmonella infection may spread beyond the intestinal tract and into the blood stream (bacteremia), which can cause life-threatening issues.

A salmonella infection is typically caused by eating food that is contaminated by fecal matter. Foods that are often contaminated include raw meat, raw poultry, raw seafood, and raw eggs, as well as contaminated fruits and vegetables. It is important for people to wash their hands before preparing food, as they may contaminate the food if they have salmonella on their hands. Risk factors include international travel and owning a bird or reptile. A salmonella infection is usually suspected based on your symptoms. Your doctor may use stool or blood testing to confirm the diagnosis. Treatments for salmonella infection include medications that stop the diarrhea (anti-diarrheal medication) and medications to treat the bacterial infection (antibiotics), but most cases get better on their own. If a person has severe diarrhea, they may need to be rehydrated by replacing fluids and electrolytes with a needle in the arm (IV). If you have been diagnosed with salmonella, talk with your doctor to discuss your treatment options.

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Condition Specific Organizations

Following organizations serve the condition "Salmonella infection" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Salmonella infection" returned 332 free, full-text research articles on human participants. First 3 results:

SipA Activation of Caspase-3 Is a Decisive Mediator of Host Cell Survival at Early Stages of Salmonella enterica Serovar Typhimurium Infection.
 

Author(s): Anne McIntosh, Lynsey M Meikle, Michael J Ormsby, Beth A McCormick, John M Christie, James M Brewer, Mark Roberts, Daniel M Wall

Journal:

 

Salmonella invasion protein A (SipA) is a dual-function effector protein that plays roles in both actin polymerization and caspase-3 activation in intestinal epithelial cells. To date its function in other cell types has remained largely unknown despite its expression in multiple ...

Last Updated: 20 Jun 2017

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Severe infection with multidrug-resistant Salmonella choleraesuis in a young patient with primary sclerosing cholangitis.
 

Author(s): Philip G Ferstl, Claudia Reinheimer, Katalin Jozsa, Stefan Zeuzem, Volkhard Aj Kempf, Oliver Waidmann, Georgios Grammatikos

Journal: World J. Gastroenterol.. 2017 Mar;23(11):2086-2089.

 

Massive global spread of multidrug-resistant (MDR) Salmonella spp. expressing extended-spectrum beta-lactamase (ESBL) and additional resistance to fluoroquinolones has often been attributed to high international mobility as well as excessive use of oral antibiotics in livestock farming. ...

Last Updated: 4 Apr 2017

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Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model.
 

Author(s): Hazel C Dobinson, Malick M Gibani, Claire Jones, Helena B Thomaides-Brears, Merryn Voysey, Thomas C Darton, Claire S Waddington, Danielle Campbell, Iain Milligan, Liqing Zhou, Sonu Shrestha, Simon A Kerridge, Anna Peters, Zoe Stevens, Audino Podda, Laura B Martin, Flavia D'Alessio, Duy Pham Thanh, Buddha Basnyat, Stephen Baker, Brian Angus, Myron M Levine, Christoph J Blohmke, Andrew J Pollard

Journal: Clin. Infect. Dis.. 2017 04;64(8):1066-1073.

 

To expedite the evaluation of vaccines against paratyphoid fever, we aimed to develop the first human challenge model of Salmonella enterica serovar Paratyphi A infection.

Last Updated: 3 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Salmonella infection" returned 21 free, full-text review articles on human participants. First 3 results:

Salmonella enterica subspecies arizonae infection of adult patients in Southern Taiwan: a case series in a non-endemic area and literature review.
 

Author(s): Yi-Chien Lee, Miao-Chiu Hung, Sheng-Che Hung, Hung-Ping Wang, Hui-Ling Cho, Mei-Chu Lai, Jann-Tay Wang

Journal:

 

The majority of Salmonella arizonae human infections have been reported in southwestern United States, where rattlesnake-based products are commonly used to treat illness; however, little is known in non-endemic areas. We reviewed and analyzed the clinical manifestations and treatment ...

Last Updated: 12 Dec 2016

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Live Attenuated Human Salmonella Vaccine Candidates: Tracking the Pathogen in Natural Infection and Stimulation of Host Immunity.
 

Author(s): James E Galen, Amanda D Buskirk, Sharon M Tennant, Marcela F Pasetti

Journal: EcoSal Plus. 2016 Nov;7(1):.

 

Salmonellosis, caused by members of the genus Salmonella, is responsible for considerable global morbidity and mortality in both animals and humans. In this review, we will discuss the pathogenesis of Salmonella enterica serovar Typhi and Salmonella enterica serovar Typhimurium, focusing ...

Last Updated: 4 Nov 2016

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Salmonella-how a metabolic generalist adopts an intracellular lifestyle during infection.
 

Author(s): Thomas Dandekar, Astrid Fieselmann, Eva Fischer, Jasmin Popp, Michael Hensel, Janina Noster

Journal:

 

The human-pathogenic bacterium Salmonella enterica adjusts and adapts to different environments while attempting colonization. In the course of infection nutrient availabilities change drastically. New techniques, "-omics" data and subsequent integration by systems biology improve ...

Last Updated: 17 Feb 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

IDIS Project Work Package 2: Establishing a Biobank at ITM and Collaborating Centres
 

Status: Recruiting

Condition Summary: Salmonella Septicemia; Salmonella Infections; Fever; Blood Stream Infections; Parasitic Infections

 

Last Updated: 13 Sep 2016

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Investigating Typhoid Fever Pathogenesis
 

Status: Recruiting

Condition Summary: Salmonella Typhi Infection

 

Last Updated: 23 May 2017

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Last Updated: 27 Sep 2017

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