Schizophrenia

Common Name(s)

Schizophrenia

Schizophrenia is a mental illness which affects social behavior and the ability to determine what is real. It is a lifelong, serious illness. Schizophrenia affects people of all genders, races, social classes and cultures. In total, the condition affects about 51 million people worldwide. Types include paranoid, disorganized, catatonic, residual, and schizoaffective.

Symptoms may include delusions, hallucinations, disorganized speech and behavior, and negative symptoms such as social withdrawal, poor hygiene and lack of inhibition. Symptoms often begin between the ages of 16 and 25 and may occur earlier in males. Schizophrenia may also cause problems with memory, attention and socialization.

The causes of schizophrenia are poorly understood but are believed to be caused by both genetics and the environment. Several genes when damaged are known to increase the risk of developing schizophrenia, but more are expected to be found. Other risk factors include exposure to malnutrition or viral infections before birth; heavy, frequent use of marijuana by teens and young adults; and problems with certain brain chemicals or neurotransmitters (dopamine and glutamate). Other factors which affect brain development may also be involved.

Diagnosis is made by examining the symptoms and ruling out other possible causes. Treatment includes antipsychotic medication and medications to help treat anxiety and depression. Group therapy may also be helpful. Treatment is lifelong, but it is often difficult to keep someone with schizophrenia on medications. Self-medication with street drugs is common. Suicide is a real concern. If you or a family member has been diagnosed with schizophrenia, talk to your psychiatrist, psychologist or therapist about the most current treatment options. A genetic counselor can help explain risks to other family members. Support groups are also good resources and can connect you with others affected by schizophrenia.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 6 Apr 2015

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Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

Last Updated: 20 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

View Details
National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 6 Apr 2015

View Details
Logo
Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

http://www.simonsvipconnect.org

Last Updated: 20 Jul 2015

View Details

 

General Support Organizations

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General Resources

Schizophrenia

A brochure for individuals and families discussing symptoms, causes, treatment and recovery supports.

Updated 29 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Schizophrenia" returned 7499 free, full-text research articles on human participants. First 3 results:

Effectiveness of integrated care including therapeutic assertive community treatment in severe schizophrenia-spectrum and bipolar I disorders: Four-year follow-up of the ACCESS II study.
 

Author(s): Daniel Schöttle, Benno G Schimmelmann, Friederike Ruppelt, Alexandra Bussopulos, Marietta Frieling, Evangelia Nika, Luise Antonia Nawara, Dietmar Golks, Andrea Kerstan, Matthias Lange, Michael Schödlbauer, Anne Daubmann, Karl Wegscheider, Anja Rohenkohl, Gizem Sarikaya, Mary Sengutta, Daniel Luedecke, Linus Wittmann, Gunda Ohm, Christina Meigel-Schleiff, Jürgen Gallinat, Klaus Wiedemann, Thomas Bock, Anne Karow, Martin Lambert

Journal:

 

The ACCESS-model offers integrated care including assertive community treatment to patients with psychotic disorders. ACCESS proved more effective compared to standard care (ACCESS-I study) and was successfully implemented into clinical routine (ACCESS-II study). In this article, ...

Last Updated: 31 Dec 1969

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Transmissibility and familiality of NEO personality dimensions in a sample of Korean families with schizophrenia.
 

Author(s): Soo Yeon Kim, Byung Dae Lee, Je Min Park, Young Min Lee, Eunsoo Moon, Hee Jeong Jeong, Young In Chung

Journal: Medicine (Baltimore). 2018 Feb;97(8):e9858.

 

Categorical syndromes such as schizophrenia may represent complexes of many continuous psychological structural phenotypes along several dimensions of personality development/degeneration. The present study investigated the heritability and familiality of Neuroticism-Extraversion-Openness ...

Last Updated: 31 Dec 1969

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Disordered high-frequency oscillation in face processing in schizophrenia patients.
 

Author(s): Miaomiao Liu, Guangying Pei, Yinuo Peng, Changming Wang, Tianyi Yan, Jinglong Wu

Journal: Medicine (Baltimore). 2018 Feb;97(6):e9753.

 

Schizophrenia is a complex disorder characterized by marked social dysfunctions, but the neural mechanism underlying this deficit is unknown. To investigate whether face-specific perceptual processes are influenced in schizophrenia patients, both face detection and configural analysis ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Schizophrenia" returned 1399 free, full-text review articles on human participants. First 3 results:

[The association of schizophrenia with chronic non transmissible diseases].
 

Author(s): Gricel Orellana, Matías Rodríguez, Nicolás González, Eduardo Durán

Journal: Rev Med Chil. 2017 Aug;145(8):1047-1053.

 

The life expectancy of patients with schizophrenia (SCH) is 11 to 20 years less than the general population. There is an association between SCH and various diseases and chronic conditions, highlighting the cardio-metabolic diseases. This association has been attributed to the use ...

Last Updated: 31 Dec 1969

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Relationship between toxoplasmosis and schizophrenia: A review.
 

Author(s): Aleksander J Fuglewicz, Patryk Piotrowski, Anna Stodolak

Journal: Adv Clin Exp Med. 2017 Sep;26(6):1031-1036.

 

A growing body of evidence suggests a correlation between schizophrenia and exposure to infectious agents. The majority of studied cases concerns the infection caused by T. gondii, an obligatory intracellular parasite that infects about 1/3 of the entire human population, according ...

Last Updated: 31 Dec 1969

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MiRNAs of peripheral blood as the biomarker of schizophrenia.
 

Author(s): Kuanjun He, Chuang Guo, Lin He, Yongyong Shi

Journal:

 

The diagnosis of schizophrenia is currently based on the symptoms and bodily signs rather than on the pathological and physiological markers of the patient. In the search for new molecular targeted therapy medicines, and recurrence of early-warning indicators have become the major ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Optimal Treatment for Treatment-resistant Schizophrenia
 

Status: Recruiting

Condition Summary: Schizophrenia

 

Last Updated: 22 Feb 2018

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Reducing Hippocampal Hyperactivity and Improving Cognition in Schizophrenia
 

Status: Not yet recruiting

Condition Summary: Schizophrenia

 

Last Updated: 22 Jan 2018

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Last Updated: 21 Nov 2017

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