Schizophrenia

Common Name(s)

Schizophrenia

Schizophrenia is a mental illness which affects social behavior and the ability to determine what is real. It is a lifelong, serious illness. Schizophrenia affects people of all genders, races, social classes and cultures. In total, the condition affects about 51 million people worldwide. Types include paranoid, disorganized, catatonic, residual, and schizoaffective.

Symptoms may include delusions, hallucinations, disorganized speech and behavior, and negative symptoms such as social withdrawal, poor hygiene and lack of inhibition. Symptoms often begin between the ages of 16 and 25 and may occur earlier in males. Schizophrenia may also cause problems with memory, attention and socialization.

The causes of schizophrenia are poorly understood but are believed to be caused by both genetics and the environment. Several genes when damaged are known to increase the risk of developing schizophrenia, but more are expected to be found. Other risk factors include exposure to malnutrition or viral infections before birth; heavy, frequent use of marijuana by teens and young adults; and problems with certain brain chemicals or neurotransmitters (dopamine and glutamate). Other factors which affect brain development may also be involved.

Diagnosis is made by examining the symptoms and ruling out other possible causes. Treatment includes antipsychotic medication and medications to help treat anxiety and depression. Group therapy may also be helpful. Treatment is lifelong, but it is often difficult to keep someone with schizophrenia on medications. Self-medication with street drugs is common. Suicide is a real concern. If you or a family member has been diagnosed with schizophrenia, talk to your psychiatrist, psychologist or therapist about the most current treatment options. A genetic counselor can help explain risks to other family members. Support groups are also good resources and can connect you with others affected by schizophrenia.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 6 Apr 2015

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Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

Last Updated: 20 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Schizophrenia" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

View Details
National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 6 Apr 2015

View Details
Logo
Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

http://www.simonsvipconnect.org

Last Updated: 20 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
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General Resources

Schizophrenia

A brochure for individuals and families discussing symptoms, causes, treatment and recovery supports.

Updated 29 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Schizophrenia" returned 7548 free, full-text research articles on human participants. First 3 results:

Achieving stable remission with maintenance electroconvulsive therapy in a patient with treatment-resistant schizophrenia: A case report.
 

Author(s): Sebastian Moeller, Neele Kalkwarf, Caroline Lücke, Diana Ortiz, Sonja Jahn, Christiane Först, Niclas Braun, Alexandra Philipsen, Helge H O Müller

Journal: Medicine (Baltimore). 2017 Dec;96(48):e8813.

 

Up to one third of all schizophrenic patients are classified as having treatment-resistant schizophrenia (TRS). This subgroup faces remarkable medical and psychosocial damages, and pharmacotherapy is often limited due to nonresponse and/or side effects. Maintenance electroconvulsive ...

Last Updated: 31 Dec 1969

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Treatment following myocardial infarction in patients with schizophrenia.
 

Author(s): Rubina Attar, Martin Berg Johansen, Jan Brink Valentin, Jørgen Aagaard, Svend Eggert Jensen

Journal:

 

A correlation between excess mortality from myocardial infarctions (MI) and schizophrenia has already been established. What remains unclear is whether the initial communication between the treating doctor and the corresponding patient contributes to this excess mortality.

Last Updated: 31 Dec 1969

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A three-month longitudinal study of changes in day/night serum total antioxidant capacity in paranoid schizophrenia.
 

Author(s): Armando L Morera-Fumero, Estefanía Díaz-Mesa, Pedro Abreu-Gonzalez, Lourdes Fernandez-Lopez, Fernando Guillen-Pino

Journal:

 

Free radicals and an oxidant/antioxidant imbalance have been involved in the schizophrenia pathophysiology. The total antioxidant capacity (TAC) is a measure of the antioxidant capacity of a system. Day/night changes are a biological characteristic of hormones such as melatonin or ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Schizophrenia" returned 1448 free, full-text review articles on human participants. First 3 results:

[The association of schizophrenia with chronic non transmissible diseases].
 

Author(s): Gricel Orellana, Matías Rodríguez, Nicolás González, Eduardo Durán

Journal: Rev Med Chil. 2017 Aug;145(8):1047-1053.

 

The life expectancy of patients with schizophrenia (SCH) is 11 to 20 years less than the general population. There is an association between SCH and various diseases and chronic conditions, highlighting the cardio-metabolic diseases. This association has been attributed to the use ...

Last Updated: 31 Dec 1969

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Causes of mortality in schizophrenia: An updated review of European studies.
 

Author(s): Patryk Piotrowski, Tomasz M Gondek, Anna Królicka-Deręgowska, Błażej Misiak, Tomasz Adamowski, Andrzej Kiejna

Journal: Psychiatr Danub. 2017 Jun;29(2):108-120.

 

The excess mortality in schizophrenia is still a phenomenon insufficiently studied on the cross-national level. It is important to analyse current studies on morality in schizophrenia since significant changes have recently taken place in psychiatric health care systems and guidelines ...

Last Updated: 31 Dec 1969

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Schizophrenia and anorexia nervosa - reciprocal relationships. A literature review.
 

Author(s): Justyna Morylowska-Topolska, Rafał Ziemiński, Agnieszka Molas, Jacek Gajewski, Marta Flis, Ewa Stelmach, Hanna Karakuła-Juchnowicz

Journal: Psychiatr. Pol.. 2017 Apr;51(2):261-270.

 

Although schizophrenia and anorexia nervosa are seemingly very distinct psychiatric disorders, their symptoms are connected by various types of relationships. The present article reviews the literature and recapitulates the views of various authors on the links between these two disorders. ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Mindfulness and Cognition in Schizophrenia
 

Status: Not yet recruiting

Condition Summary: Schizophrenia

 

Last Updated: 23 Oct 2017

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The Optimal Treatment for Treatment-resistant Schizophrenia
 

Status: Not yet recruiting

Condition Summary: Schizophrenia

 

Last Updated: 5 Oct 2016

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Reducing Hippocampal Hyperactivity and Improving Cognition in Schizophrenia
 

Status: Not yet recruiting

Condition Summary: Schizophrenia

 

Last Updated: 14 Jun 2017

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