Seizures

Common Name(s)

Seizures, Epileptic seizure

Seizures occur when there is abnormal electrical activity in the brain. Chemical changes in our nerve cells trigger the electrical activity in our body. Brain cells either trigger or stop other brain cells from sending messages throughout the body. During a seizure there is either too much or too little activity going on in the brain cells. This causes the sudden electrical activity that leads to seizures. Since there are different types of seizures, the location of the abnormal activity in the brain sets one seizure apart from another.

Non-epileptic seizures are seizures that occur from injuries. In partial seizures, the abnormal activity occurs in only one side of the brain. This results in only one side of the body experiencing the seizure. Generalized seizures affect both sides of the brain. Each seizure has different symptoms. Brief blackout, twitching and jerking movements, sudden falling, shaking of the entire body, sudden eye movements, change in behavior, loss of bladder control, loss of speech control, and teeth clenching are a few symptoms of seizures.

Seizures are often a symptom of other health conditions. They may result from high fever, head injury, infections, trauma, stroke, drug abuse, electric shock, extremely high blood pressure, alcohol withdrawal, and drug withdrawal. Doctors diagnose seizures by running a test called electroencephalogram (EEG). This test checks the brain for unusual electrical activity. There are many types of medications available to treat this condition. If medication does not work, then surgery may be an option. Talk with your doctor to decide which treatment plan is best for you. Support groups are also good resources for support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Seizures" for support, advocacy or research.

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Epilepsy Foundation - Home Office

The mission of the Epilepsy Foundation is to stop seizures and SUDEP, find a cure and overcome the challenges created by epilepsy through efforts including education, advocacy and research to accelerate ideas into therapies.

Last Updated: 28 Apr 2015

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Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

Last Updated: 20 Jul 2015

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The Arc of East Central Iowa

The Arc of East Central Iowa empowers people with intellectual and related disabilities to engage in lifelong opportunities to live, learn, work and play with dignity, freedom and full inclusion in their communities.

Last Updated: 11 Apr 2013

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Zellweger Baby Support Network

This organization was started by a small group of parents whose lives have been affected in some way by a rare disorder. Our gift, in honor of our children, was to start this site, so we can help families and to raise awareness of these rare disorders. If your child has been diagnosed with Zellweger syndrome, a peroxisomal disorder or another rare disorder, we are here to help you. You are not alone! Our mission is to promote, advance, and improve awareness of Zellweger syndrome and other peroxisomal disorders, to assist, support, and aid, financially or otherwise, individuals and families affected by Zellweger syndrome. We will help you learn more about these disorders. We will provide emotional support, and we can help you to create a journal site for your child so that family and friends can be kept up to date on your child. We will pray with you and for you as you journey through life with your special angel. We know this is a hard time for you; you want answers, informa

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Seizures" for support, advocacy or research.

Logo
Epilepsy Foundation - Home Office

The mission of the Epilepsy Foundation is to stop seizures and SUDEP, find a cure and overcome the challenges created by epilepsy through efforts including education, advocacy and research to accelerate ideas into therapies.

http://www.epilepsy.com

Last Updated: 28 Apr 2015

View Details
Logo
Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

http://www.simonsvipconnect.org

Last Updated: 20 Jul 2015

View Details
The Arc of East Central Iowa

The Arc of East Central Iowa empowers people with intellectual and related disabilities to engage in lifelong opportunities to live, learn, work and play with dignity, freedom and full inclusion in their communities.

http://www.arceci.org

Last Updated: 11 Apr 2013

View Details
Logo
Zellweger Baby Support Network

This organization was started by a small group of parents whose lives have been affected in some way by a rare disorder. Our gift, in honor of our children, was to start this site, so we can help families and to raise awareness of these rare disorders. If your child has been diagnosed with Zellweger syndrome, a peroxisomal disorder or another rare disorder, we are here to help you. You are not alone! Our mission is to promote, advance, and improve awareness of Zellweger syndrome and other peroxisomal disorders, to assist, support, and aid, financially or otherwise, individuals and families affected by Zellweger syndrome. We will help you learn more about these disorders. We will provide emotional support, and we can help you to create a journal site for your child so that family and friends can be kept up to date on your child. We will pray with you and for you as you journey through life with your special angel. We know this is a hard time for you; you want answers, informa

http://www.zbsn.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Seizures" returned 2492 free, full-text research articles on human participants. First 3 results:

SCN8A mutations in Chinese patients with early onset epileptic encephalopathy and benign infantile seizures.
 

Author(s): Jiaping Wang, Hua Gao, Xinhua Bao, Qingping Zhang, Jiarui Li, Liping Wei, Xiru Wu, Yan Chen, Shujie Yu

Journal:

 

SCN8A mutations have recently been associated with epilepsy and neurodevelopmental disorders. This study aimed to broaden the phenotypic-spectrum of disease related with SCN8A mutations.

Last Updated: 19 Sep 2017

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Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome.
 

Author(s): Orrin Devinsky, J Helen Cross, Stephen Wright

Journal: N. Engl. J. Med.. 2017 08;377(7):699-700.

 

Last Updated: 16 Aug 2017

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Risk factors associated with the development of seizures among adult patients treated with ertapenem: A matched case-control study.
 

Author(s): Yi-Chien Lee, Yun-Jhong Huang, Miao-Chiu Hung, Sheng-Che Hung, Chih-Yen Hsiao, Hui-Ling Cho, Li-Fen Lai, Show-Hwa Tong, Jann-Tay Wang

Journal:

 

The purpose of this study is to compare the characteristics of those ertapenem-treated adult patients with and without development of seizures, and identify the associated factors for the development of seizures.

Last Updated: 31 Jul 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Seizures" returned 325 free, full-text review articles on human participants. First 3 results:

[Research advances in circadian rhythm of epileptic seizures].
 

Author(s): Wen-Qi Yang, Hong Li

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2017 Jan;19(1):126-129.

 

The time phase of epileptic seizures has attracted more and more attention. Epileptic seizures have their own circadian rhythm. The same type of epilepsy has different seizure frequencies in different time periods and states (such as sleeping/awakening state and natural day/night ...

Last Updated: 19 Jan 2017

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[Psychogenic non-epileptic seizures in children].
 

Author(s): Morten I Lossius, Antonia Villagran, Hilde N Karterud, Oliver Henning, Karl O Nakken

Journal:

 

Last Updated: 22 Dec 2016

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Generation of Febrile Seizures and Subsequent Epileptogenesis.
 

Author(s): Bo Feng, Zhong Chen

Journal: Neurosci Bull. 2016 Oct;32(5):481-92.

 

Febrile seizures (FSs) occur commonly in children aged from 6 months to 5 years. Complex (repetitive or prolonged) FSs, but not simple FSs, can lead to permanent brain modification. Human infants and immature rodents that have experienced complex FSs have a high risk of subsequent ...

Last Updated: 22 Sep 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Levetiracetam Treatment of Neonatal Seizures
 

Status: Recruiting

Condition Summary: Neonatal Seizures

 

Last Updated: 15 Dec 2016

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Epidemiology Study on Neonatal Seizure
 

Status: Recruiting

Condition Summary: Seizures

 

Last Updated: 17 Oct 2017

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Efficacy of Levetiracetam in Control of Neonatal Seizures Guided by an EEG
 

Status: Recruiting

Condition Summary: Neonatal Seizures

 

Last Updated: 5 Apr 2017

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