Sepsis

Common Name(s)

Sepsis

Sepsis is a severe reaction to a bacterial infection anywhere in the body. Symptoms include an increased heart rate, fever, rapid breathing, weakness, and feeling ill. Sepsis can cause damage to many important organ systems in the body. Septic shock occurs when sepsis progresses and a person's blood pressure drops, which is very dangerous and may lead to death. Sepsis is most common in elderly people and those with weakened immune systems. It can usually be treated with antibiotics and intravenous fluids.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sepsis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Sepsis" returned 3664 free, full-text research articles on human participants. First 3 results:

Factors associated with severe sepsis or septic shock in complicated pyelonephritis.
 

Author(s): Juan D Ruiz-Mesa, Ignacio Marquez-Gomez, Gabriel Sena, Veronica A Buonaiuto, Juan Mora Ordoñez, Manuel Salido, Antonio Plata Ciézar, Lucía Valiente-De Santis, Concepción Mediavilla, Juan D Colmenero

Journal: Medicine (Baltimore). 2017 Oct;96(43):e8371.

 

Severe sepsis or septic shock are the main factors influencing the prognosis of acute pyelonephritis (APN). Our aim was to analyze factors associated with the development of severe sepsis or septic shock in a large sample of patients with acute complicated pyelonephritis (ACPN).This ...

Last Updated: 25 Oct 2017

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Sepsis kills one million newborns a year: WHO.
 

Author(s): Lauren Vogel

Journal: CMAJ. 2017 10;189(40):E1272.

 

Last Updated: 11 Oct 2017

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Thrombocytopenia in neonatal sepsis: Incidence, severity and risk factors.
 

Author(s): Isabelle M C Ree, Suzanne F Fustolo-Gunnink, Vincent Bekker, Karin J Fijnvandraat, Sylke J Steggerda, Enrico Lopriore

Journal:

 

Thrombocytopenia is a frequent problem in neonatal sepsis and is among the most predictive, independent risk factors for sepsis-associated mortality. This study aims to clarify the occurrence, severity and duration of thrombocytopenia in neonatal sepsis.

Last Updated: 4 Oct 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Sepsis" returned 733 free, full-text review articles on human participants. First 3 results:

The role of group IIA secretory phospholipase A2 (sPLA2-IIA) as a biomarker for the diagnosis of sepsis and bacterial infection in adults-A systematic review.
 

Author(s): Toh Leong Tan, Yew Yip Goh

Journal:

 

This paper investigates the role of Group II Secretory Phospholipase A2 (sPLA2-IIA) as a biomarker for the diagnosis of sepsis and bacterial infection in adults. Sepsis and bacterial infection are common problems encountered by patients in the hospital and often carry adverse outcomes ...

Last Updated: 3 Jul 2017

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Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and children with systemic inflammatory syndrome: a meta-analysis.
 

Author(s): Giuseppe Pontrelli, Franco De Crescenzo, Roberto Buzzetti, Alessandro Jenkner, Sara Balduzzi, Francesca Calò Carducci, Donato Amodio, Maia De Luca, Sara Chiurchiù, Elin Haf Davies, Giorgia Copponi, Alessandra Simonetti, Elena Ferretti, Valeria Di Franco, Virginia Rasi, Martina Della Corte, Luca Gramatica, Marco Ciabattini, Susanna Livadiotti, Paolo Rossi

Journal:

 

A number of biomarkers have been studied for the diagnosis of sepsis in paediatrics, but no gold standard has been identified. Procalcitonin (PCT) was demonstrated to be an accurate biomarker for the diagnosis of sepsis in adults and showed to be promising in paediatrics. Our study ...

Last Updated: 25 Apr 2017

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Programmed Cell Death-1/Programmed Death-ligand 1 Pathway: A New Target for Sepsis.
 

Author(s): Qiang Liu, Chun-Sheng Li

Journal: Chin. Med. J.. 2017 Apr;130(8):986-992.

 

Sepsis remains a leading cause of death in many Intensive Care Units worldwide. Immunosuppression has been a primary focus of sepsis research as a key pathophysiological mechanism. Given the important role of the negative costimulatory molecules programmed cell death-1 (PD-1) and ...

Last Updated: 11 Apr 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 18 Sep 2017

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The Efficacy of Xuebijing Injection on Sepsis
 

Status: Recruiting

Condition Summary: Sepsis

 

Last Updated: 3 Oct 2017

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Efficacy of Thymosin Alpha 1 on Improving Monocyte Function for Sepsis
 

Status: Recruiting

Condition Summary: Sepsis

 

Last Updated: 24 Aug 2016

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