Sepsis

Common Name(s)

Sepsis

Sepsis is a severe reaction to a bacterial infection anywhere in the body. Symptoms include an increased heart rate, fever, rapid breathing, weakness, and feeling ill. Sepsis can cause damage to many important organ systems in the body. Septic shock occurs when sepsis progresses and a person's blood pressure drops, which is very dangerous and may lead to death. Sepsis is most common in elderly people and those with weakened immune systems. It can usually be treated with antibiotics and intravenous fluids.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sepsis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Sepsis" returned 3496 free, full-text research articles on human participants. First 3 results:

Treprostinil for persistent pulmonary hypertension of the newborn, with early onset sepsis in preterm infant: 2 Case reports.
 

Author(s): Bo Young Park, Sung-Hoon Chung

Journal: Medicine (Baltimore). 2017 Jun;96(26):e7303.

 

Persistent pulmonary hypertension of the newborn (PPHN) is a syndrome of failed circulatory adaptation at birth with persisting increased pulmonary vascular resistance that is associated with high mortality rates especially in preterm infants.

Last Updated: 28 Jun 2017

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China's growing contribution to sepsis research from 1984 to 2014: A bibliometric study.
 

Author(s): Kai Zhang, Jialian Zhao, Lihua Chu, Yue Jin, Baoli Cheng, Guohao Xie, Yan Wang, Xiangming Fang

Journal: Medicine (Baltimore). 2017 Jun;96(25):e7275.

 

The aim of this study was to analyze the global trends of sepsis research and investigate China's contribution by comparing the quantity and quality of sepsis-related publications.

Last Updated: 22 Jun 2017

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Development and validation of a mortality risk model for pediatric sepsis.
 

Author(s): Mengshi Chen, Xiulan Lu, Li Hu, Pingping Liu, Wenjiao Zhao, Haipeng Yan, Liang Tang, Yimin Zhu, Zhenghui Xiao, Lizhang Chen, Hongzhuan Tan

Journal: Medicine (Baltimore). 2017 May;96(20):e6923.

 

Pediatric sepsis is a burdensome public health problem. Assessing the mortality risk of pediatric sepsis patients, offering effective treatment guidance, and improving prognosis to reduce mortality rates, are crucial.We extracted data derived from electronic medical records of pediatric ...

Last Updated: 17 May 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Sepsis" returned 701 free, full-text review articles on human participants. First 3 results:

The Glyoxalase System and Methylglyoxal-Derived Carbonyl Stress in Sepsis: Glycotoxic Aspects of Sepsis Pathophysiology.
 

Author(s): Thomas Schmoch, Florian Uhle, Benedikt H Siegler, Thomas Fleming, Jakob Morgenstern, Peter P Nawroth, Markus A Weigand, Thorsten Brenner

Journal:

 

Sepsis remains one of the leading causes of death in intensive care units. Although sepsis is caused by a viral, fungal or bacterial infection, it is the dysregulated generalized host response that ultimately leads to severe dysfunction of multiple organs and death. The concomitant ...

Last Updated: 17 Mar 2017

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Pro-Resolving Molecules-New Approaches to Treat Sepsis?
 

Author(s): Christa Buechler, Rebekka Pohl, Charalampos Aslanidis

Journal:

 

Inflammation is a complex response of the body to exogenous and endogenous insults. Chronic and systemic diseases are attributed to uncontrolled inflammation. Molecules involved in the initiation of inflammation are very well studied while pathways regulating its resolution are insufficiently ...

Last Updated: 28 Feb 2017

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Mechanisms of endothelial activation in sepsis and cell culture models to study the heterogeneous host response.
 

Author(s): Tanja Eichhorn, Michael B Fischer, Viktoria Weber

Journal: Int J Artif Organs. 2017 Mar;40(1):9-14.

 

Sepsis is currently viewed as a fundamental disintegration of control functions from intracellular signalling to immunoregulatory and neuroendocrine mechanisms. The immediate threat in sepsis is invasive infection, and the need to activate immune defense mechanisms to clear the pathogen ...

Last Updated: 20 Feb 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Efficacy of Thymosin Alpha 1 on Improving Monocyte Function for Sepsis
 

Status: Recruiting

Condition Summary: Sepsis

 

Last Updated: 24 Aug 2016

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The Efficacy and Safety of Ta1 for Sepsis
 

Status: Recruiting

Condition Summary: Sepsis

 

Last Updated: 27 Mar 2017

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Last Updated: 7 Feb 2017

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