Sepsis

Common Name(s)

Sepsis

Sepsis is a severe reaction to a bacterial infection anywhere in the body. Symptoms include an increased heart rate, fever, rapid breathing, weakness, and feeling ill. Sepsis can cause damage to many important organ systems in the body. Septic shock occurs when sepsis progresses and a person's blood pressure drops, which is very dangerous and may lead to death. Sepsis is most common in elderly people and those with weakened immune systems. It can usually be treated with antibiotics and intravenous fluids.

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sepsis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Sepsis" returned 3567 free, full-text research articles on human participants. First 3 results:

Neutrophil CD64 as a diagnostic marker for neonatal sepsis: Meta-analysis.
 

Author(s): Ji Dai, Wenjie Jiang, Zhigang Min, Jian Yang, Yongfei Tan, Tieliang Ma, Zhijun Ge

Journal: Adv Clin Exp Med. ;26(2):327-332.

 

Neutrophil CD64 (nCD64) is a promising marker for diagnosing bacterial infections. Several studies have investigated the performance of nCD64 for diagnosing neonatal sepsis and the results are variable. Interest in nCD64 for detecting serious bacterial infections is increasing rapidly.

Last Updated: 9 Aug 2017

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Sepsis due to Streptococcus pneumoniae associated with secondary hemophagocytic lymphohistiocytosis in a splenectomized patient for spherocytosis: A case report.
 

Author(s): Victoria Birlutiu, Rares Mircea Birlutiu

Journal: Medicine (Baltimore). 2017 Jul;96(28):e7520.

 

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome that is characterized by an inappropriate hyperinflammatory immune response - primary, as a consequence of a genetic defect of NK cells and cytotoxic T lymphocytes or - secondary, in the progression of infections, rheumatic or ...

Last Updated: 12 Jul 2017

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Recognizing Sepsis as a Global Health Priority - A WHO Resolution.
 

Author(s): Konrad Reinhart, Ron Daniels, Niranjan Kissoon, Flavia R Machado, Raymond D Schachter, Simon Finfer

Journal: N. Engl. J. Med.. 2017 Aug;377(5):414-417.

 

Last Updated: 28 Jun 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Sepsis" returned 719 free, full-text review articles on human participants. First 3 results:

Programmed Cell Death-1/Programmed Death-ligand 1 Pathway: A New Target for Sepsis.
 

Author(s): Qiang Liu, Chun-Sheng Li

Journal: Chin. Med. J.. 2017 Apr;130(8):986-992.

 

Sepsis remains a leading cause of death in many Intensive Care Units worldwide. Immunosuppression has been a primary focus of sepsis research as a key pathophysiological mechanism. Given the important role of the negative costimulatory molecules programmed cell death-1 (PD-1) and ...

Last Updated: 11 Apr 2017

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The Glyoxalase System and Methylglyoxal-Derived Carbonyl Stress in Sepsis: Glycotoxic Aspects of Sepsis Pathophysiology.
 

Author(s): Thomas Schmoch, Florian Uhle, Benedikt H Siegler, Thomas Fleming, Jakob Morgenstern, Peter P Nawroth, Markus A Weigand, Thorsten Brenner

Journal:

 

Sepsis remains one of the leading causes of death in intensive care units. Although sepsis is caused by a viral, fungal or bacterial infection, it is the dysregulated generalized host response that ultimately leads to severe dysfunction of multiple organs and death. The concomitant ...

Last Updated: 17 Mar 2017

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Pro-Resolving Molecules-New Approaches to Treat Sepsis?
 

Author(s): Christa Buechler, Rebekka Pohl, Charalampos Aslanidis

Journal:

 

Inflammation is a complex response of the body to exogenous and endogenous insults. Chronic and systemic diseases are attributed to uncontrolled inflammation. Molecules involved in the initiation of inflammation are very well studied while pathways regulating its resolution are insufficiently ...

Last Updated: 28 Feb 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Efficacy of Xuebijing Injection on Sepsis
 

Status: Not yet recruiting

Condition Summary: Sepsis

 

Last Updated: 3 Aug 2017

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Efficacy of Thymosin Alpha 1 on Improving Monocyte Function for Sepsis
 

Status: Recruiting

Condition Summary: Sepsis

 

Last Updated: 24 Aug 2016

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The Efficacy and Safety of Ta1 for Sepsis
 

Status: Recruiting

Condition Summary: Sepsis

 

Last Updated: 27 Mar 2017

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