Shigellosis

Common Name(s)

Shigellosis

Shigellosis is a contagious illness caused by the Shigella bacterium. There are four different types of Shigella which cause diarrhea. The bacteria are present in the fecal matter (bowel movement) of infected individuals. Shigella bacteria are often spread by touching contaminated hands to the mouth, by eating/drinking contaminated food or water, or through person to person contact. Shigella cannot live outside the body for long. Children, childcare workers, and those with weak immune systems are the most likely to be infected. However, not all infected people develop symptoms.

Symptoms of shigellosis begin 1 to 2 days after exposure to the bacteria and may include fever, diarrhea, and stomach cramps. Symptoms generally last 5 to 7 days. Shigellosis may be difficult to diagnose because the symptoms are common to other illnesses. Lab tests of the stool or fecal matter can determine the bacteria type and if antibiotics will help.

Complications include post-infectious arthritis, blood stream infections, seizures, and hemolytic-uremic syndrome. Post-infectious arthritis symptoms include joint pain, eye irritation, and painful urination, which may last only a few months or may be permanent. Blood stream infections usually occur in individuals with weak immune systems by germs entering the blood stream through damaged lining of the intestines. Children with a high fever may experience seizures. Hemolytic-uremic syndrome occurs when bacteria in the digestive system produce toxins to destroy red blood cells, causing bloody diarrhea.

Treatment for shigellosis includes drinking fluids and rest. In most cases, the body will clear the bacterial infection on its own. Antibiotics may be used in severe cases, although some Shigella bacteria are resistant. Common hygiene methods such as washing hands with soap can reduce the spread of shigellosis. If you are suffering from shigellosis, talk to your doctor about the most current treatment options.

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Condition Specific Organizations

Following organizations serve the condition "Shigellosis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Shigellosis" returned 162 free, full-text research articles on human participants. First 3 results:

Shigellosis and toxic megacolon secondary to Shigella flexneri serotype 3a: The challenges of laboratory diagnosis.
 

Author(s): Emma McGuire, Simon Tiberi, Holly Ciesielczuk, Mark Melzer

Journal: Int. J. Infect. Dis.. 2018 May;70():104-106.

 

We present a rare case of Shigella flexneri bacteraemia and toxic megacolon, and discuss the challenges of conventional laboratory techniques versus molecular PCR platforms in differentiating between Shigella species and Escherichia coli.

Last Updated: 31 Dec 1969

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Disparities in severe shigellosis among adults - Foodborne diseases active surveillance network, 2002-2014.
 

Author(s): Lindsey S McCrickard, Stacy M Crim, Sunkyung Kim, Anna Bowen

Journal:

 

Shigella causes approximately 500,000 illnesses, 6000 hospitalizations, and 40 deaths in the United States annually, but incidence and populations at risk for severe shigellosis among adults are unclear. This study describes severe shigellosis among US adults.

Last Updated: 31 Dec 1969

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An adult case with shigellosis-associated encephalopathy.
 

Author(s): Heleen Joséphine Schuster, Michelle Gompelman, Wim Ang, Albertus Jozef Kooter

Journal:

 

A 45-year-old man was presented at the emergency department with altered neurological status and a 1-day history of diarrhoea and fever. The patient's sexual history revealed multiple male partners. As bacterial meningitis or viral encephalitis was suspected, treatment was started ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Shigellosis" returned 9 free, full-text review articles on human participants. First 3 results:

Shigellosis: Epidemiology in India.
 

Author(s): Neelam Taneja, Abhishek Mewara

Journal: Indian J. Med. Res.. 2016 May;143(5):565-76.

 

Shigellosis is one of the major causes of diarrhoea in India. The accurate estimates of morbidity and mortality due to shigellosis are lacking, though it is endemic in the country and has been reported to cause many outbreaks. The limited information available indicates Shigella to ...

Last Updated: 31 Dec 1969

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Causative species and serotypes of shigellosis in mainland China: systematic review and meta-analysis.
 

Author(s): Zhili Chang, Shuting Lu, Lihong Chen, Qi Jin, Jian Yang

Journal: PLoS ONE. 2012 ;7(12):e52515.

 

Shigella, the causative agent of shigellosis, is a major global public health concern, particularly in developing countries with poor sanitation. A comprehensive and current understanding of the prevalent species and serotypes of shigellosis is essential for both disease prevention ...

Last Updated: 31 Dec 1969

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Decrease in shigellosis-related deaths without Shigella spp.-specific interventions, Asia.
 

Author(s): Pradip Bardhan, A S G Faruque, Aliya Naheed, David A Sack

Journal: Emerging Infect. Dis.. 2010 Nov;16(11):1718-23.

 

In 1999, a review of the literature for 1966-1997 suggested that ≈1.1 million persons die annually of shigellosis, including ≈880,000 in Asia. Our recent review of the literature for 1990-2009 indicates that ≈125 million shigellosis cases occur annually in Asia, of which ≈14,000 ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Phase 1 Study of dmLT ID Vaccination in Healthy Adults
 

Status: Recruiting

Condition Summary: Gastroenteritis Escherichia Coli

 

Last Updated: 12 Oct 2017

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