Soft tissue sarcoma

Common Name(s)

Soft tissue sarcoma

Soft-tissue sarcomas are cancerous tumors that begin in the soft tissues of the body. This stype of sarcoma is rare in adults and not very common in children. Symptoms of soft-tissue sarcomas are not noticeable initially, but as the tumor grows, several of the following may develop: a lump or swelling, a blockage in the stomach or intestines if the tumor is located in the abdomen or digestive tract, and pain, particularly if the tumor sits on or near a bundle of nerves. Soft-tissue sarcomas can go by a variety of names, depending on the location of origination, and include disorders such as Kaposi’s sasrcoma, synovial sarcoma, liposarcoma, fibrosaroma, and neurofibrosarcoma.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Soft tissue sarcoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Soft tissue sarcoma" returned 553 free, full-text research articles on human participants. First 3 results:

A congenital soft tissue Ewing sarcoma in a newborn patient.
 

Author(s): Mustafa Akçalı, Hacer Yapıcıoğlu, Eray Akay, Ferda Özlü, Banu Kozanoğlu, Kıvılcım Erdoğan, Gülfiliz Gönlüşen, Mehmet Satar

Journal: Turk. J. Pediatr.. 2017 ;59(1):76-79.

 

Akçalı M, Yapıcıoğlu H, Akay E, Özlü F, Kozanoğlu B, Erdoğan K, Gönlüşen G, Satar M. A congenital soft tissue Ewing sarcoma in a newborn patient. Turk J Pediatr 2017; 59: 76-79. < p < Congenital Ewing sarcoma is extremely rare. Here we present a newborn baby born with ...

Last Updated: 31 Dec 1969

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Exposure-survival analyses of pazopanib in renal cell carcinoma and soft tissue sarcoma patients: opportunities for dose optimization.
 

Author(s): R B Verheijen, L E Swart, J H Beijnen, J H M Schellens, A D R Huitema, N Steeghs

Journal: Cancer Chemother. Pharmacol.. 2017 Dec;80(6):1171-1178.

 

Pazopanib is an angiogenesis inhibitor approved for the treatment of renal cell carcinoma and soft tissue sarcoma. Post hoc analysis of a clinical trial demonstrated a relationship between pazopanib trough concentrations (C) and treatment efficacy. The aim of this study was to explore ...

Last Updated: 31 Dec 1969

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The fate of new fosfamides in phase III studies in advanced soft tissue sarcoma.
 

Author(s): Anastasia Constantinidou, Winette T A van der Graaf

Journal: Eur. J. Cancer. 2017 10;84():257-261.

 

For decades, doxorubicin alone or in combination with ifosfamide has been used in advanced soft tissue sarcoma (STS). In 2014, a comparison of doxorubicin alone versus the combination with ifosfamide (in the randomised phase III EORTC 62012) showed no difference in overall survival ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Soft tissue sarcoma" returned 59 free, full-text review articles on human participants. First 3 results:

Systemic treatment in advanced soft tissue sarcoma: what is standard, what is new.
 

Author(s): Anna Maria Frezza, Silvia Stacchiotti, Alessandro Gronchi

Journal:

 

For metastatic soft tissue sarcoma (STS) patients not eligible for surgery, systemic treatments, including standard chemotherapy and newer biological compounds, still play the most relevant role in the management of the disease. An anthracycline and alkylating agent combination has ...

Last Updated: 31 Dec 1969

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Systemic Therapy for Soft Tissue Sarcoma: Proposals for the Optimal Use of Pazopanib, Trabectedin, and Eribulin.
 

Author(s): Akira Kawai, Kan Yonemori, Shunji Takahashi, Nobuhito Araki, Takafumi Ueda

Journal: Adv Ther. 2017 Jul;34(7):1556-1571.

 

Soft tissue sarcoma (STS) is a rare tumor with more than 50 histologic subtypes. Although treatment outcomes for patients with STS have improved greatly over the past few decades owing to the adoption of a multidisciplinary approach, patients with advanced disease have a poor prognosis. ...

Last Updated: 31 Dec 1969

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Phase III Soft Tissue Sarcoma Trials: Success or Failure?
 

Author(s): Alexander T J Lee, Seth M Pollack, Paul Huang, Robin L Jones

Journal: Curr Treat Options Oncol. 2017 Mar;18(3):19.

 

Two recently reported phase III randomised control trials (RCTs) have resulted in the registration of two new systemic therapies for advanced soft tissue sarcoma. Both of these trials' designs were informed by phase II data that guided the selection of sensitive STS diagnoses, enabling ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 6 Jun 2017

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Last Updated: 30 Aug 2017

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Last Updated: 23 Oct 2017

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