Spasticity

Common Name(s)

Spasticity

Spasticity is a muscular condition characterized by involuntary movements and stiffness. Affected individuals will experience resistance when attempting movements due to muscles being involuntarily contracted. This condition may make small movements, such as buttoning a shirt, very difficult. Spasticity is caused by injury to the brain, spinal cord, or nerves as a result of trauma, stroke, or neuromuscular disorders. This injury results in abnormal signaling between the brain and muscles, causing the abnormal contraction of muscles. Many stroke survivors and over 80% of individuals with multiple sclerosis are affected by spasticity.

Common signs of spasticity include abnormal posture, a clenched fist, and flexed elbows, hands, or fingers. Individuals affected by spasticity may experience symptoms ranging from minor stiffness and inflexibility to involuntary and painful spasms. Other symptoms include difficulty speaking, jerky motions, pain with movement, and very strong reflexes. When an individual has severe spasticity for a long time, their muscle may decrease in size. This may lead to reduced range of motion or the inability to move a joint from a fixed position.

Diagnosis and treatment of spasticity are important to minimize symptoms in affected individuals. Proper treatment can reduce limitations, prevent further injury, and improve quality of life. Treatment for spasticity depends on the severity of the symptoms and overall health of the affected individual. Braces are often used to keep a muscle in a desired position. Physical therapy and exercises often help to strengthen muscles, maintain full range of motion, and reduce risk of permanent muscle damage. Medications taken as pills, injections, and/or implanted devices may be used to help relax muscles. If you or your child has been diagnosed with spasticity, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Spasticity" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Spasticity" returned 423 free, full-text research articles on human participants. First 3 results:

Novel Treatment Using Intravenous Dantrolene Sodium for Postoperative Exacerbated Spasticity in Multiple Sclerosis: A Case Report.
 

Author(s): Emily L Sturgill, Robert L Wittwer

Journal: A A Pract. 2018 Jul;11(1):25-27.

 

Patients with upper motor neuron disease, such as multiple sclerosis, can present with severe spasticity in the perioperative period. In most cases, this can be managed with a combination of preoperative oral medications, regional or neuraxial anesthetic techniques, and intravenous ...

Last Updated: 31 Dec 1969

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Path analysis of strength, spasticity, gross motor function, and health-related quality of life in children with spastic cerebral palsy.
 

Author(s): Eun-Young Park

Journal:

 

Measures of health-related quality of life may predict the future status of individuals with illnesses, and could therefore be a good indicator in children with cerebral palsy (CP). This study examines the causal relationship between spasticity, weakness, gross motor function, and ...

Last Updated: 31 Dec 1969

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Physical therapy in patients with disorders of consciousness: Impact on spasticity and muscle contracture.
 

Author(s): A Thibaut, S Wannez, T Deltombe, G Martens, S Laureys, C Chatelle

Journal: NeuroRehabilitation. 2018 ;42(2):199-205.

 

Spasticity is a frequent complication after severe brain injury, which may prevent the rehabilitation process and worsen the patients' quality of life.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Spasticity" returned 58 free, full-text review articles on human participants. First 3 results:

Towards flexible and tailored botulinum neurotoxin dosing regimens for focal dystonia and spasticity - Insights from recent studies.
 

Author(s): Jörg Wissel

Journal: Toxicon. 2018 Jun;147():100-106.

 

Botulinum neurotoxin (BoNT) is an effective, well-tolerated, and well-established option for the treatment of dystonic and spastic movement disorders. However, a single approach does not suit all patients, even within one disease indication. The degree of flexibility in treatment ...

Last Updated: 31 Dec 1969

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[Calpain as a new therapeutic target for treating spasticity after a spinal cord injury].
 

Author(s): Vanessa Plantier, Frédéric Brocard

Journal: Med Sci (Paris). ;33(6-7):629-636.

 

After a spinal cord injury (SCI), patients develop spasticity, a motor disorder characterized by hyperreflexia and stiffness of muscles. Spasticity results from alterations in motoneurons with an upregulation of their persistent sodium current (I ), simultaneously with a disinhibition ...

Last Updated: 31 Dec 1969

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Influence of transcutaneous electrical nerve stimulation on spasticity, balance, and walking speed in stroke patients: A systematic review and meta-analysis.
 

Author(s): Shuqin Lin, Qi Sun, Haifeng Wang, Guomin Xie

Journal: J Rehabil Med. 2018 Jan;50(1):3-7.

 

To evaluate the influence of transcutaneous electrical nerve stimulation in patients with stroke through a systematic review and meta-analysis.

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Peripheral Modulation of Muscle Stiffness and Spasticity
 

Status: Not yet recruiting

Condition Summary: Muscle Spasticity

 

Last Updated: 8 Oct 2018

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Study of the Effects on Motor Recovery of Early Post-stroke Spasticity Treatment
 

Status: Recruiting

Condition Summary: Muscle Spasticity

 

Last Updated: 13 Dec 2016

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