Spinal shock

Common Name(s)

Spinal shock

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Spinal shock" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Spinal shock" returned 11 free, full-text research articles on human participants. First 3 results:

Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury.
 

Author(s): Daniela Lobenwein, Can Tepeköylü, Radoslaw Kozaryn, Elisabeth J Pechriggl, Mario Bitsche, Michael Graber, Helga Fritsch, Severin Semsroth, Nadia Stefanova, Patrick Paulus, Martin Czerny, Michael Grimm, Johannes Holfeld

Journal:

 

Paraplegia following spinal cord ischemia represents a devastating complication of both aortic surgery and endovascular aortic repair. Shock wave treatment was shown to induce angiogenesis and regeneration in ischemic tissue by modulation of early inflammatory response via Toll-like ...

Last Updated: 28 Oct 2015

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Heat shock proteins HSP70 and HSP27 in the cerebral spinal fluid of patients undergoing thoracic aneurysm repair correlate with the probability of postoperative paralysis.
 

Author(s): James G Hecker, Hari Sundram, Shaomin Zou, Amy Praestgaard, Joseph E Bavaria, Sindhu Ramchandren, Michael McGarvey

Journal: Cell Stress Chaperones. 2008 Dec;13(4):435-46.

 

An understanding of the time course and correlation with injury of heat shock proteins (HSPs) released during brain and/or spinal cord cellular stress (ischemia) is critical in understanding the role of the HSPs in cellular survival, and may provide a clinically useful biomarker of ...

Last Updated: 21 Oct 2008

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Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein.
 

Author(s): Hiroaki Adachi, Masahisa Katsuno, Makoto Minamiyama, Chen Sang, Gerassimos Pagoulatos, Charalampos Angelidis, Moriaki Kusakabe, Atsushi Yoshiki, Yasushi Kobayashi, Manabu Doyu, Gen Sobue

Journal: J. Neurosci.. 2003 Mar;23(6):2203-11.

 

Spinal and bulbar muscular atrophy (SBMA) is an inherited motor neuron disease caused by the expansion of the polyglutamine (polyQ) tract within the androgen receptor (AR). The nuclear inclusions consisting of the mutant AR protein are characteristic and combine with many components ...

Last Updated: 26 Mar 2003

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Spinal shock" returned 3 free, full-text review articles on human participants. First 3 results:

Heat shock proteins as biomarkers for the rapid detection of brain and spinal cord ischemia: a review and comparison to other methods of detection in thoracic aneurysm repair.
 

Author(s): James G Hecker, Michael McGarvey

Journal: Cell Stress Chaperones. 2011 Mar;16(2):119-31.

 

The heat shock proteins (HSPs) are members of highly conserved families of molecular chaperones that have multiple roles in vivo. We discuss the HSPs in general, and Hsp70 and Hsp27 in particular, and their rapid induction by severe stress in the context of tissue and organ expression ...

Last Updated: 28 Jan 2011

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Spinal shock--comparative aspects and clinical relevance.
 

Author(s): P M Smith, N D Jeffery

Journal: J. Vet. Intern. Med.. ;19(6):788-93.

 

Spinal shock is the loss of muscle tone and segmental spinal reflexes that develops caudal to a severe spinal cord injury. Although little recognized in the veterinary literature, spinal shock occurs in animals and is important in both accurate lesion localization and case management. ...

Last Updated: 16 Dec 2005

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Spinal shock: possible role of receptor plasticity and non synaptic transmission.
 

Author(s): P Bach-y-Rita, L S Illis

Journal: Paraplegia. 1993 Feb;31(2):82-7.

 

Spinal shock remains an enigma. To date there has been no convincing explanation of the recovery of reflexes following their complete abolition. Volume transmission includes both the activation of extrasynaptic receptors, and activity induced by substances diffusing into synaptic ...

Last Updated: 6 Apr 1993

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Predict Fluid Responsiveness in Spinal Anesthesia
 

Status: Recruiting

Condition Summary: Hypotension and Shock; Excessive Amount of Blood / Fluid Infusion

 

Last Updated: 13 Aug 2016

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