Spotted fever

Common Name(s)

Spotted fever

Spotted fever is an infectious disease caused by certain types of Rickettsial bacteria. The bacteria are transmitted though tick bites. There are four types of spotted fever: Mediterranean spotted fever, Rocky Mountain spotted fever, Queensland tick typhus, and Helvetica spotted fever. Spotted fevers are difficult to diagnose at first. Common initial symptoms include fever, muscle pains, headache, nausea and vomiting. Later symptoms includes a spotted rash, joint pain, pains in the abdomen or stomach area and forgetfullness. Diagnosis is made usually by the combination of fever, skin rash and known tick bite. Blood tests may also be performed. Most types of spotted fever are mild to moderate illnesses. However if left untreated they can become potentially serious and even fatal, especially in older people and in people whose immune system (the body's defense system against disease and infection) is weak. The most serious type of the spotted fever is the Rocky Mountain spotted fever, and many people affected with Rocky Mountain spotted fever require hospitalization. Antibiotics are used to treat spotted fevers, and if the infection becomes more serious, other symptoms are treated as needed. If you or a family member has been bitten by a tick and develops a fever and skin rash, it is important to go to your doctor.

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Condition Specific Organizations

Following organizations serve the condition "Spotted fever" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Spotted fever" returned 291 free, full-text research articles on human participants. First 3 results:

Fatal Rocky Mountain Spotted Fever along the United States-Mexico Border, 2013-2016.
 

Author(s): Naomi A Drexler, Hayley Yaglom, Mariana Casal, Maria Fierro, Paula Kriner, Brian Murphy, Anne Kjemtrup, Christopher D Paddock

Journal: Emerging Infect. Dis.. 2017 10;23(10):1621-1626.

 

Rocky Mountain spotted fever (RMSF) is an emerging public health concern near the US-Mexico border, where it has resulted in thousands of cases and hundreds of deaths in the past decade. We identified 4 patients who had acquired RMSF in northern Mexico and subsequently died at US ...

Last Updated: 31 Dec 1969

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Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium.
 

Author(s): Abha Sahni, Jignesh Patel, Hema P Narra, Casey L C Schroeder, David H Walker, Sanjeev K Sahni

Journal:

 

Rickettsial infections continue to cause serious morbidity and mortality in severe human cases around the world. Host cell adhesion and invasion is an essential requisite for intracellular growth, replication, and subsequent dissemination of pathogenic rickettsiae. Heparan sulfate ...

Last Updated: 31 Dec 1969

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Seroprevalence of Scrub Typhus, Typhus, and Spotted Fever Among Rural and Urban Populations of Northern Vietnam.
 

Author(s): Nguyen Vu Trung, Le Thi Hoi, Nguyen Thi Hong Thuong, Tran Khanh Toan, Tran Thi Kieu Huong, Tran Mai Hoa, Annette Fox, Nguyen van Kinh, H Rogier van Doorn, Heiman F L Wertheim, Juliet E Bryant, Behzad Nadjm

Journal: Am. J. Trop. Med. Hyg.. 2017 May;96(5):1084-1087.

 

AbstractRickettsial infections are recognized as important causes of fever throughout southeast Asia. Herein, we determined the seroprevalence to rickettsioses within rural and urban populations of northern Vietnam. Prevalence of individuals with evidence of prior rickettsial infections ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Spotted fever" returned 16 free, full-text review articles on human participants. First 3 results:

Israeli Spotted Fever in Sicily. Description of two cases and minireview.
 

Author(s): Claudia Colomba, Marcello Trizzino, Anna Giammanco, Celestino Bonura, Danilo Di Bona, Manlio Tolomeo, Antonio Cascio

Journal: Int. J. Infect. Dis.. 2017 Aug;61():7-12.

 

Mediterranean spotted fever (MSF) is endemic in Italy, where Rickettsia conorii subsp. conorii was thought to be the only pathogenic rickettsia and Rhipicephalus sanguineus the vector and main reservoir. R. conorii subsp. israelensis, which belongs to the R. conorii complex, is the ...

Last Updated: 31 Dec 1969

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State of the art of diagnosis of rickettsial diseases: the use of blood specimens for diagnosis of scrub typhus, spotted fever group rickettsiosis, and murine typhus.
 

Author(s): Daniel H Paris, J Stephen Dumler

Journal: Curr. Opin. Infect. Dis.. 2016 Oct;29(5):433-9.

 

With improved malaria control, acute undifferentiated febrile illness studies in tropical regions reveal a startling proportion of rickettsial illnesses, especially scrub typhus, murine typhus, and spotted fever group rickettsioses. Laboratory diagnosis of these infections evolved ...

Last Updated: 31 Dec 1969

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Atypical Rocky Mountain spotted fever with polyarticular arthritis.
 

Author(s): Muhammad A Chaudhry, Robert Hal Scofield

Journal: Am. J. Med. Sci.. 2013 Nov;346(5):427-9.

 

Rocky Mountain spotted fever (RMSF) is an acute, serious tick borne illness caused by Rickettsia rickettsi. Frequently, RMSF is manifested by headache, a typical rash and fever but atypical disease is common, making diagnosis difficult. Inflammatory arthritis as a manifestation is ...

Last Updated: 31 Dec 1969

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