Synovial cancer

Common Name(s)

Synovial cancer

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Synovial cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Synovial cancer" returned 5 free, full-text research articles on human participants. First 3 results:

Trabectedin in advanced synovial sarcomas: a multicenter retrospective study from four European institutions and the Italian Rare Cancer Network.
 

Author(s): Roberta Sanfilippo, Palma Dileo, Jean-Yves Blay, Anastasia Constantinidou, Axel Le Cesne, Charlotte Benson, Laura Vizzini, Marianna Contu, Giacomo G Baldi, Angelo P Dei Tos, Paolo G Casali

Journal: Anticancer Drugs. 2015 Jul;26(6):678-81.

 

Treatment options for patients with metastatic synovial sarcoma are limited. Over recent years, trabectedin has emerged as an effective agent for patients with advanced soft tissue sarcomas resistant to anthracyclines and ifosfamide. The aim of this retrospective analysis was to study ...

Last Updated: 27 May 2015

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Involvement of breast cancer resistance protein expression on rheumatoid arthritis synovial tissue macrophages in resistance to methotrexate and leflunomide.
 

Author(s): Joost W van der Heijden, Ruud Oerlemans, Paul P Tak, Yehuda G Assaraf, Maarten C Kraan, George L Scheffer, Conny J van der Laken, Willem F Lems, Rik J Scheper, Ben A C Dijkmans, Gerrit Jansen

Journal: Arthritis Rheum.. 2009 Mar;60(3):669-77.

 

To determine whether multidrug-resistance efflux transporters are expressed on immune effector cells in synovial tissue from patients with rheumatoid arthritis (RA) and compromise the efficacy of methotrexate (MTX) and leflunomide (LEF).

Last Updated: 9 Mar 2009

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Expression of synovial sarcoma X (SSX) antigens in epithelial ovarian cancer and identification of SSX-4 epitopes recognized by CD4+ T cells.
 

Author(s): Danila Valmori, Feng Qian, Maha Ayyoub, Christoph Renner, Andrea Merlo, Sacha Gnjatic, Sacha Gjnatic, Elisabeth Stockert, Deborah Driscoll, Shashikant Lele, Lloyd J Old, Kunle Odunsi

Journal: Clin. Cancer Res.. 2006 Jan;12(2):398-404.

 

Synovial sarcoma X (SSX) breakpoint genes are expressed in a variety of cancers but not in normal tissues, except for testis, and are potential targets for immunotherapy. The aims of this study were to determine the expression and immunogenicity of these antigens in patients with ...

Last Updated: 23 Jan 2006

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Synovial cancer" returned 1 free, full-text review articles on human participants. First 3 results:

Of mice and men: opportunities to use genetically engineered mouse models of synovial sarcoma for preclinical cancer therapeutic evaluation.
 

Author(s): Kevin B Jones, Malay Haldar, Joshua D Schiffman, Lisa Cannon-Albright, Stephen L Lessnick, Sunil Sharma, Mario R Capecchi, R Lor Randall

Journal: Cancer Control. 2011 Jul;18(3):196-203.

 

Synovial sarcoma is a soft tissue malignancy with a predilection for adolescents and young adults. Despite recent improvements in the understanding of its character and etiology, few therapeutic advances have been made. The mortality rate is high among the young population it affects. ...

Last Updated: 13 Jun 2011

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Phase 1 Study of the EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma
 

Status: Recruiting

Condition Summary: Rhabdoid Tumors; INI1-negative Tumors; Synovial Sarcoma; Malignant Rhabdoid Tumor of Ovary

 

Last Updated: 2 Aug 2017

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A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma
 

Status: Recruiting

Condition Summary: Malignant Rhabdoid Tumors (MRT); Rhabdoid Tumors of the Kidney (RTK); Atypical Teratoid Rhabdoid Tumors (ATRT); Selected Tumors With Rhabdoid Features; Synovial Sarcoma; INI1-negative Tumors; Malignant Rhabdoid Tumor of Ovary; Renal Medullary Carcinoma; Epithelioid Sarcoma; Poorly Differentiated Chordoma (or Other Chordoma With Sponsor Approval); Any Solid Tumor With an EZH2 GOF Mutation

 

Last Updated: 13 Nov 2017

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T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer
 

Status: Recruiting

Condition Summary: Melanoma; Synovial Sarcoma; Breast Cancer; Non-Small Cell Lung Cancer; Hepatocellular Cancer

 

Last Updated: 18 Oct 2017

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