Synovial sarcoma

Common Name(s)

Synovial sarcoma

Synovial sarcoma is rare and aggressive soft tissue sarcoma that appears as deep, painless, slowly growing masses. Most frequently the tumor affects the legs, especially the knees, and the arms. Less frequently, this disease develops in the trunk, head and neck region, or the abdomen. Although synovial sarcoma does not have a clearly defined cause, genetic factors are believed to influence the development of this disease. Cells in these tumors are usually characterized by the presence of a translocation involving chromosomes X and 18. This translocation is specific to synovial sarcoma and is often used to diagnose this cancer. Although this condition generally affects adults, about 30% of reported cases occur in children and adolescents.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Synovial sarcoma" for support, advocacy or research.

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Synovial sarcoma" for support, advocacy or research.

Logo
Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

View Details
Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

View Details
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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Synovial sarcoma" returned 316 free, full-text research articles on human participants. First 3 results:

Prognostic impact of the tumor immune microenvironment in synovial sarcoma.
 

Author(s): Naoki Oike, Hiroyuki Kawashima, Akira Ogose, Tetsuo Hotta, Hiroshi Hatano, Takashi Ariizumi, Taro Sasaki, Tetsuro Yamagishi, Hajime Umezu, Naoto Endo

Journal: Cancer Sci.. 2018 Oct;109(10):3043-3054.

 

The association between the immune status within the tumor microenvironment and prognosis in synovial sarcoma is not well understood. We aimed to investigate the tumor immune microenvironment and analyze its prognostic impact for patients with synovial sarcoma. A total of 36 primary ...

Last Updated: 31 Dec 1969

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Treatment of cardiac synovial sarcoma: experience of two cases.
 

Author(s): Antonella Coli, Giovanni Alfonso Chiariello, Mariangela Novello, Christian Colizzi, Massimo Massetti

Journal:

 

Primary heart sarcomas are exceedingly rare tumors. Among primary cardiac sarcomas, synovial sarcoma is one of the rarest, involving cardiac cavities or pericardium.

Last Updated: 31 Dec 1969

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α-particle therapy for synovial sarcoma in the mouse using an astatine-211-labeled antibody against frizzled homolog 10.
 

Author(s): Huizi Keiko Li, Aya Sugyo, Atsushi B Tsuji, Yukie Morokoshi, Katsuyuki Minegishi, Kotaro Nagatsu, Hiroaki Kanda, Yosuke Harada, Satoshi Nagayama, Toyomasa Katagiri, Yusuke Nakamura, Tatsuya Higashi, Sumitaka Hasegawa

Journal: Cancer Sci.. 2018 Jul;109(7):2302-2309.

 

Synovial sarcoma (SS) is a rare yet refractory soft-tissue sarcoma that predominantly affects young adults. We show in a mouse model that radioimmunotherapy (RIT) with an α-particle emitting anti-Frizzled homolog 10 (FZD10) antibody, synthesized using the α-emitter radionuclide ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Synovial sarcoma" returned 36 free, full-text review articles on human participants. First 3 results:

Primary synovial sarcoma of the kidney: a case report of complete pathological response at a Lebanese tertiary care center.
 

Author(s): Alissar El Chediak, Deborah Mukherji, Sally Temraz, Samer Nassif, Sara Sinno, Rami Mahfouz, Ali Shamseddine

Journal:

 

Primary synovial sarcoma of the kidney is a rare type of soft tissue sarcoma. Its presenting features can resemble those of other renal tumors; rendering its early diagnosis, a dilemma. Several cases of renal synovial sarcoma have been reported in the literature with varying treatment ...

Last Updated: 31 Dec 1969

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Primary renal synovial sarcoma: A case report and literature review.
 

Author(s): Yong Huang, Dawei Liu, Junhang Luo, Wei Chen

Journal: J Cancer Res Ther. 2018 ;14(Supplement):S267-S269.

 

Synovial sarcomas (SSs) are very rare, poorly studied tumors that generally occurs around joint and muscle tendons. Primary SSs of the kidney are even rarer, accounting for <2% of all malignant renal tumors. We report the case of a 44-year-old man who was diagnosed with primary renal ...

Last Updated: 31 Dec 1969

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[Initial manifestation and atypical site for metastatic synovial sarcoma in an immunocompetent adult patient: about a case and literature review].
 

Author(s): Amina Atmane, Sanaa Hammi, Asmâa Regragui, Mohammed Raoufi, Karima Marc, Mouna Soualhi, Rachida Zahraoui, Jouda Benamor, Jamal Eddine Bourkadi

Journal:

 

Synovial sarcoma (SS) is a rare tumor. It is characterized by various sites of occurrence but rarely involves the chest. The tumor may be wrongly diagnosed as benign due to its slow growth. Less than 10% of patients present with metastatic cancer. Endobronchial metastases are exceptional. ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 7 Sep 2018

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Last Updated: 27 Sep 2018

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DHEA in Synovial Sarcoma Patients
 

Status: Recruiting

Condition Summary: Synovial Sarcoma; Sarcoma, Synovial

 

Last Updated: 5 Sep 2018

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