Syringomyelia

Common Name(s)

Syringomyelia

Syringomyelia is a disorder in which a cyst, called a syrinx, forms within the spinal cord. This cyst expands and elongates over time, destroying the center of the spinal cord which can result in pain, weakness, stiffness in the back, shoulders, arms, or legs, headaches, and insensitivity to temperature (especially in the hands). Symptoms vary from person to person. Syringomyelia is often related to a congenital abnormality of the brain called a Chiari I malformation, but may also occur as a complication of trauma, meningitis, hemorrhage, a tumor, or arachnoiditis. Symptoms may appear months or even years after the initial injury. Some cases of syringomyelia are familial, although this is rare. Treatment often involves surgery and avoiding activities that involve straining. Drainage of the cysts using a catheter, drainage tubes, and valves may be required in some patients. If not treated, the disorder can lead to progressive weakness in the arms and legs, loss of hand sensation, and chronic, severe pain.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Syringomyelia" for support, advocacy or research.

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American Syringomyelia & Chiari Alliance Project, Inc.

To improve the lives of people affected by syringomyelia, Chiari malformation and related disorders, while we find the cure.

Last Updated: 30 Oct 2012

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

Last Updated: 18 Mar 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Syringomyelia" for support, advocacy or research.

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American Syringomyelia & Chiari Alliance Project, Inc.

To improve the lives of people affected by syringomyelia, Chiari malformation and related disorders, while we find the cure.

http://www.asap.org

Last Updated: 30 Oct 2012

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

http://www.CSFinfo.org

Last Updated: 18 Mar 2013

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General Resources

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Related Disorders Lecture Series

Updated 7 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Syringomyelia" returned 237 free, full-text research articles on human participants. First 3 results:

Pan, Syrinx and syringomyelia.
 

Author(s): Leonardo Palacios-Sánchez, Juan Sebastián Botero-Meneses, María Camila Vélez-Flórez

Journal: Arq Neuropsiquiatr. 2017 Dec;75(12):890-891.

 

Many myths and legends have had a deep influence on modern language, and on modern medical vernacular. The terms "syrinx" and "panic"are two of the most characteristic examples and their use in neurology and other specialties is well known. This article reviews the history of these ...

Last Updated: 31 Dec 1969

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Asymptomatic syringomyelia accompanied with metastatic cerebellar and spinal intramedullary lymphoma: A case report.
 

Author(s): Jia-Jia Zhou, Jin-Feng Xu, Xu-Ning Zheng, Guo-Ping Peng

Journal: Medicine (Baltimore). 2017 Nov;96(46):e8593.

 

Asympotamic syringomyelia accompanied with metastatic cerebellar and thoracic spinal intramedullary lymphoma is rare in clinical practice. If the intramedullary lymphoma is large enough, the patient will rapidly develop neurologic signs of spinal injury. The prognosis of this type ...

Last Updated: 31 Dec 1969

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Syringomyelia Fluid Dynamics and Cord Motion Revealed by Serendipitous Null Point Artifacts during Cine MRI.
 

Author(s): C M Honey, K W Martin, M K S Heran

Journal: AJNR Am J Neuroradiol. 2017 Sep;38(9):1845-1847.

 

Dynamic MR imaging was used to evaluate a cervical syrinx in an adolescent boy with an associated hindbrain herniation. Null artifacts were present on one of the sequences that allowed simultaneous high-resolution visualization of syrinx fluid motion and the anatomy of the syrinx ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Syringomyelia" returned 18 free, full-text review articles on human participants. First 3 results:

Charcot arthropathy of the shoulder joint as a presenting feature of basilar impression with syringomyelia: A case report and literature review.
 

Author(s): Xin Wang, Yongning Li, Jun Gao, Tianyu Wang, Zhimin Li

Journal: Medicine (Baltimore). 2018 Jul;97(28):e11391.

 

Charcot arthropathy, also known as Neuropathic arthropathy (NA), is an unusual chronic degenerative disease. To date, there exists a paucity of research on NA caused by syringomyelia.

Last Updated: 31 Dec 1969

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[Syringosubarachnoid shunting in treatment of syringomyelia: a literature review and a clinical case report].
 

Author(s): V S Klimov, Yu S Gulay, A V Evsyukov, G I Moysak

Journal: Zh Vopr Neirokhir Im N N Burdenko. ;81(3):58-65.

 

In the article, we describe a clinical case of syringomyelia associated with an Arnold-Chiari type 1 malformation, evaluate the efficacy of syringosubarachnoid shunting, and analyze the literature data of domestic and international researchers involved in investigation and treatment ...

Last Updated: 31 Dec 1969

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[Treatment of syringomyelia in patients with Chiari malformation and craniosynostosis. A case report and review of the literature].
 

Author(s): A Aransay-Garcia, F J Villarejo-Ortega

Journal: Rev Neurol. 2016 Nov;63(10):455-459.

 

Patients with multisutural or single craniosynostosis, often suffer from Chiari malformation and syringomyelia. The surgical management of syringomyelia in these patients is controversial.

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Prospective Natural History Study of Patients With Syringomyelia
 

Status: Recruiting

Condition Summary: Syringomyelia; Arnold Chiari Deformity

 

Last Updated: 8 Aug 2018

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Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia
 

Status: Recruiting

Condition Summary: Arnold-Chiari Malformation, Type 1; Chiari Malformation Type I; Type I Arnold-Chiari Malformation; Syringomyelia

 

Last Updated: 14 Mar 2018

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Genetic Analysis of the Chiari I Malformation
 

Status: Recruiting

Condition Summary: Syringomyelia; Type I Arnold Chiari Malformation

 

Last Updated: 1 Sep 2018

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