Takayasu arteritis

Common Name(s)

Takayasu arteritis, Takayasu's arteritis, TAK, Pulseless disease, Aortic arch syndrome

Takayasu’s arteritis is a rare form of blood vessel inflammation (vasculitis) that typically affects the large artery that carries blood from your heart to the rest of your body (the aorta), as well as the artery that carries blood from the heart to the lungs (pulmonary artery). Signs and symptoms of Takayasu’s arteritis often occur in two stages. The first stage (systemic stage) may include symptoms such general fatigue, fever, headache, fast and unintentional weight loss, joint pain and sore muscles. The second stage (occlusive stage) develops when inflammation causes the affected arteries to narrow. This narrowing can cause a decrease in blood flow along with a decrease in the amount of oxygen and nutrients that can reach tissues and organs. Symptoms of the second stage can include dizziness, visual problems, shortness of breath, chest or abdominal pain, weakness, change in limb color, fainting, stroke, seizure, or high blood pressure. Symptoms depend on which arteries are inflamed.

The exact cause of Takayasu’s arteritis is not known. The inflamed arteries are believed to be caused by an autoimmune disease, which means the body’s immune cells attack the tissue in the arteries, mistaking it for something foreign (from outside the body). To diagnose the condition, a doctor will collect a medical history, conduct a physical exam, perform blood tests and collect images of the heart, chest and arteries. In some cases, Takayasu’s arteritis can be managed by medication. However, if it becomes severe enough, surgery may be necessary. If you are diagnosed with Takayasu’s arteritis, talk with your doctor to discuss the right treatment plan for you.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Takayasu arteritis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Takayasu arteritis" returned 172 free, full-text research articles on human participants. First 3 results:

An unrecognised presentation of Takayasu arteritis: superficial femoral artery involvement.
 

Author(s): Hui Dong, Wuqiang Che, Xiongjing Jiang, Meng Peng, Yubao Zou, Huimin Zhang, Bo Xu, Yuejin Yang, Runlin Gao

Journal: Clin. Exp. Rheumatol.. ;35 Suppl 103(1):83-87.

 

Superficial femoral artery (SFA) involvement in Takayasu arteritis (TAK) has rarely been reported. The purpose of this study was to investigate the clinical characteristic and clinical outcomes of endovascular therapy in such patients.

Last Updated: 2 Dec 2016

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Optical coherence tomography imaging during endovascular treatment of a patient with Takayasu arteritis.
 

Author(s): Maciej Lewandowski, Małgorzata Peregud-Pogorzelska, Paweł Stachowiak, Marek Brzosko, Zdzisława Kornacewicz-Jach

Journal: Kardiol Pol. ;74(7):697.

 

Last Updated: 12 Jul 2016

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Cause of death in Chinese Takayasu arteritis patients.
 

Author(s): Jing Li, Mengzhu Zhu, Mengtao Li, Wenjie Zheng, Jiuliang Zhao, Xinping Tian, Xiaofeng Zeng

Journal: Medicine (Baltimore). 2016 Jul;95(27):e4069.

 

To analyze the causes of death and the related risk factors for in-patients with Takayasu arteritis (TAK) admitted to a referral center of China during 1983 to 2014.The medical charts of 12 deceased TAK patients (10 women, 2 men) were reviewed by two senior rheumatologists. The demographic ...

Last Updated: 12 Jul 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Takayasu arteritis" returned 10 free, full-text review articles on human participants. First 3 results:

Aortic rupture during aortoplasty in Takayasu arteritis--a rare complication: case report and review of literature.
 

Author(s): Vimal Mehta, Bhagya Narayan Pandit, Jamal Yusuf, Saibal Mukhopadhyay, Jagdeep Yadav, Vijay Trehan, Sanjay Tyagi

Journal: Indian Heart J. ;66(3):350-4.

 

Balloon angioplasty of the stenosed aorta is usually a relatively simple, yet potentially a catastrophic procedure. Aortic rupture during aortoplasty, though uncommon, carries a high mortality. We report case of a 39-year-old female with aortoarteritis with multiple arterial stenoses ...

Last Updated: 30 Jun 2014

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Takayasu arteritis as a cause of arterial hypertension. Case report and literature review.
 

Author(s): Elżbieta Sadurska, Renata Jawniak, Marek Majewski, Elżbieta Czekajska-Chehab

Journal: Eur. J. Pediatr.. 2012 May;171(5):863-9.

 

We report a 16-year-old girl in whom Takayasu arteritis (TA) was manifested mainly by severe arterial hypertension on her right arm, which was detected during a routine examination at school. Her systolic blood pressure on the right arm was significantly higher than that on the left ...

Last Updated: 1 Jun 2012

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Takayasu arteritis with intracranial involvement mimicking epilepsy: case report and review of the literature.
 

Author(s): Zahit Bolaman, Irfan Yavasoglu, Gurhan Kadikoylu, Mustafa Unubol, Kutsi Koseoglu, Ali Akyol

Journal: Intern. Med.. 2011 ;50(12):1345-8.

 

The symptoms of Takayasu arteritis (TA) are related to end organ ischemia. Here we present a patient with convulsions and intracranial involvement. A 15-year-old young woman was admitted with the complaint of convulsions since one and a half months previously. Her physical examination ...

Last Updated: 15 Jun 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

China Takayasu Arteritis Registry (CTA Registry)
 

Status: Recruiting

Condition Summary: TAKAYASU ARTERITIS

 

Last Updated: 13 Nov 2016

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Registration Study of Takayasu's Arteritis in China
 

Status: Not yet recruiting

Condition Summary: Takayasu Arteritis

 

Last Updated: 23 Jun 2017

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Takayasu Arteritis Clinical Trial in China
 

Status: Not yet recruiting

Condition Summary: Takayasu Arteritis

 

Last Updated: 1 Dec 2016

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