Tetanus

Common Name(s)

Tetanus, Lockjaw

Tetanus, also called "lockjaw", is a disease caused by a bacterial infection from Clostridium tetani which can be found in dirt, dust, or animal feces. Infection occurs from contact with the bacteria through open skin wounds. The bacteria affects muscular activity, and can cause spasms, stiffness, and other discomfort. There is a tetanus vaccine available and a booster shot that you can receive if you have a deep or dirty wound. Treatment given usually includes wound care, antibiotics, and bedrest.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tetanus" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tetanus" returned 981 free, full-text research articles on human participants. First 3 results:

Non-protective immunity against tetanus in primiparous women and newborns at birth in rural and urban settings in Ibadan, Nigeria.
 

Author(s): Adebola Emmanuel Orimadegun, Bose Etaniamhe Orimadegun, Elijah Afolabi Bamgboye

Journal:

 

Nigeria remains among the few countries that are yet to achieve eradication of neonatal tetanus in the world despite the availability of an effective vaccine. This study investigated immunity against tetanus in primiparous mothers and neonates at birth, and identified associated factors.

Last Updated: 31 Dec 1969

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The impact of antenatal care, iron-folic acid supplementation and tetanus toxoid vaccination during pregnancy on child mortality in Bangladesh.
 

Author(s): Tanvir Abir, Felix Akpojene Ogbo, Garry John Stevens, Andrew Nicolas Page, Abul Hasnat Milton, Kingsley Emwinyore Agho

Journal:

 

Appropriate antenatal care (ANC) is an important preventive public health intervention to ensure women's and newborn health outcomes. The study aimed to investigate the impact of ANC, iron-folic acid (IFA) supplementation and tetanus toxoid (TT) vaccination during pregnancy on child ...

Last Updated: 31 Dec 1969

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Long-term outcome in survivors of neonatal tetanus following specialist intensive care in Vietnam.
 

Author(s): Huynh T Trieu, Nguyen Thi Kim Anh, Huynh Ngoc Thien Vuong, T T M Dao, Nguyen Thi Xuan Hoa, Vo Ngoc Cat Tuong, Pham Tam Dinh, Bridget Wills, Phan Tu Qui, Le Van Tan, Lam Minh Yen, Saraswathy Sabanathan, Catherine Louise Thwaites

Journal:

 

Neonatal tetanus continues to occur in many resource-limited settings but there are few data regarding long-term neurological outcome from the disease, especially in settings with critical care facilities.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tetanus" returned 40 free, full-text review articles on human participants. First 3 results:

Strategies to increase immunization coverage of tetanus vaccine among women in Sub Saharan Africa: a systematic review.
 

Author(s): Marius Zambou Vouking, Carine Nouboudem Tadenfok, Jean Marie Edengue Ekani

Journal:

 

World Health Organization (WHO) estimated in 2013 that 49,000 deaths all over the world were caused by neonatal tetanus. Only as recently as the year 2000, neonatal tetanus was a public health problem in 59 countries, but since then it has been eliminated in 36 of the countries concerned. ...

Last Updated: 31 Dec 1969

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Progress towards achieving and maintaining maternal and neonatal tetanus elimination in the African region.
 

Author(s): Alison Delano Ridpath, Heather Melissa Scobie, Messeret Eshetu Shibeshi, Ahmadu Yakubu, Flint Zulu, Azhar Abid Raza, Balcha Masresha, Rania Tohme

Journal:

 

Despite the availability of effective tetanus prevention strategies, as of 2016, Maternal and Neonatal Tetanus Elimination (MNTE) has not yet been achieved in 18 countries globally. In this paper, we review the status of MNTE in the World Health Organization African Region (AFR),and ...

Last Updated: 31 Dec 1969

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Adult vaccination against tetanus and diphtheria: the European perspective.
 

Author(s): B Weinberger

Journal: Clin. Exp. Immunol.. 2017 Jan;187(1):93-99.

 

Besides immunizations against influenza, Streptococcus pneumoniae and herpes zoster, which are recommended specifically for elderly people, regular booster vaccinations against tetanus, diphtheria and in some cases pertussis and polio are recommended in many European countries for ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Intrathecal Tetanus Immunoglobulin to Treat Tetanus
 

Status: Recruiting

Condition Summary: Tetanus

 

Last Updated: 8 Apr 2018

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Last Updated: 18 Jun 2018

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