Thrombotic thrombocytopenic purpura, acquired

Common Name(s)

Thrombotic thrombocytopenic purpura, acquired

Thrombotic thrombocytopenic purpura (TTP), acquired is a blood disorder characterized by low platelets (i.e., thrombocytopenia), small areas of bleeding under the skin (i.e., purpura), low red blood cell count, and hemolytic anemia. TTP causes blood clots (thrombi) to form in small blood vessels throughout the body. These clots can cause serious medical problems if they block vessels and restrict blood flow to organs such as the brain, kidneys, and heart. Resulting complications can include neurological problems (such as personality changes, headaches, confusion, and slurred speech), fever, abnormal kidney function, abdominal pain, and heart problems. Hemolytic anemia can lead to paleness, yellowing of the eyes and skin (jaundice), fatigue, shortness of breath, and a rapid heart rate. TTP, acquired usually appears in late childhood or adulthood. Affected individuals may have a single episode of signs and symptoms, or they may recur over time. This condition results from a reduction in ADAMTS13 enzyme activity caused by autoantibodies.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thrombotic thrombocytopenic purpura, acquired" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

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Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thrombotic thrombocytopenic purpura, acquired" returned 0 free, full-text research articles on human participants.

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The terms "Thrombotic thrombocytopenic purpura, acquired" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Observational Study of the Use of octaplasLG®.
 

Status: Recruiting

Condition Summary: Thrombotic Thrombocytopenic Purpura

 

Last Updated: 6 Nov 2018

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Magnesium Sulfate in Thrombotic Thrombocytopenic Purpura in Intensive Care
 

Status: Not yet recruiting

Condition Summary: Thrombotic Thrombocytopenic Purpura

 

Last Updated: 7 Dec 2017

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