Thyroid Cancer

Common Name(s)

Thyroid Cancer

Thyroid cancer occurs in the cells of the thyroid. The thyroid is responsible for producing hormones that regulate heart rate, blood pressure, body temperature, and weight. Typically, in the early stages of thyroid cancer, there are no symptoms. However, as the cancer progresses one may have the following symptoms: a lump that can be felt through the skin on one’s neck, changes to one’s voice, difficulty swallowing, pain in neck and throat, or swollen lymph nodes in the neck. Thyroid cancer remains relatively rare in the United States, but is becoming more common as new technology enables doctors to find small thyroid cancers that may not have been detected previously. Treatment options are dependent on the individual’s type and stage of thyroid cancer.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Thyroid Cancer Forum-UK

On line information for patients on thyroid cancer including: Background information on the thyroid gland Incidence and Risk factors Symptoms Types of thyroid cancer Diagnosis and staging investigations Treatment: surgery, thyroxine, radioiodine, mIBG, radiotherapy Follow up Prognosis Clinical Trials Electronic links to other sites for information and support

Last Updated: 21 Jan 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Thyroid Cancer Forum-UK

On line information for patients on thyroid cancer including: Background information on the thyroid gland Incidence and Risk factors Symptoms Types of thyroid cancer Diagnosis and staging investigations Treatment: surgery, thyroxine, radioiodine, mIBG, radiotherapy Follow up Prognosis Clinical Trials Electronic links to other sites for information and support

http://www.thyroid-cancer-forum-uk.org

Last Updated: 21 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thyroid Cancer" returned 2163 free, full-text research articles on human participants. First 3 results:

Asymptomatic intrathyroidal pyriform sinus fistula mimicking thyroid cancer: A case report and literature review.
 

Author(s): Soo Chin Kim, Ji-Hoon Kim, Jae-Kyung Won, Eun Jae Chung

Journal: Medicine (Baltimore). 2018 Apr;97(16):e0488.

 

There have been many reports of non-thyroidal lesions which can be mistaken for thyroidal lesions on ultrasound (US) examination. However, it is not known that pyriform sinus fistula (PSF) can manifest as an incidental thyroid nodule and cause serious complication on fine-needle aspiration (FNA).

Last Updated: 31 Dec 1969

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Is the ratio superior to the number of metastatic lymph nodes in addressing the response in patients with papillary thyroid cancer?
 

Author(s): Wen Gao, Teng Zhao, Jun Liang, Yansong Lin

Journal: Medicine (Baltimore). 2018 Jan;97(3):e9664.

 

The number of metastatic lymph nodes (LNs) and the ratio of metastatic LN (LR) have been reported as predictors of recurrence in papillary thyroid carcinoma (PTC), while the role of LR or the number of metastatic LNs on the clinical response remains unclear.

Last Updated: 31 Dec 1969

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CHK2 Promotes Anoikis and is Associated with the Progression of Papillary Thyroid Cancer.
 

Author(s): Wenjing Zhao, Shaobo Chen, Xianming Hou, Ge Chen, Yupei Zhao

Journal: Cell. Physiol. Biochem.. 2018 ;45(4):1590-1602.

 

Cell cycle checkpoint kinase 2 (CHK2) performs essential cellular functions and might be associated with tumorigenesis and tumor progression. Here, we explored the function and molecular mechanisms of CHK2 in the progression of papillary thyroid cancer (PTC).

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Thyroid Cancer" returned 322 free, full-text review articles on human participants. First 3 results:

Radiofrequency ablation for treatment of locally recurrent thyroid cancer presenting as a metastatic lymph node with dense macrocalcification: A case report and literature review.
 

Author(s): Roh-Eul Yoo, Ji-Hoon Kim, Jin Chul Paeng, Young Joo Park

Journal: Medicine (Baltimore). 2018 Mar;97(9):e0003.

 

Long-term recurrence rate of differentiated thyroid carcinoma has been reported to be as high as 30%. Repeat surgery may be challenging due to normal tissue plane distortion secondary to postoperative fibrosis, especially for small-sized recurrences. Recently, radiofrequency ablation ...

Last Updated: 31 Dec 1969

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Novel concepts for initiating multitargeted kinase inhibitors in radioactive iodine refractory differentiated thyroid cancer.
 

Author(s): R Michael Tuttle, Marcia S Brose, Enrique Grande, Sun Wook Kim, Makoto Tahara, Mona M Sabra

Journal: Best Pract. Res. Clin. Endocrinol. Metab.. 2017 06;31(3):295-305.

 

Multitargeted kinase inhibitors have been shown to improve progression-free survival in patients with structurally progressive, radioactive iodine refractory differentiated thyroid cancer. While the inclusion criteria for phase 3 clinical trials and clinical practice guidelines provide ...

Last Updated: 31 Dec 1969

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Key signaling pathways in thyroid cancer.
 

Author(s): Miguel A Zaballos, Pilar Santisteban

Journal: J. Endocrinol.. 2017 Nov;235(2):R43-R61.

 

Whole genome sequencing approaches have provided unprecedented insights into the genetic lesions responsible for the onset, progression and dedifferentiation of various types of thyroid carcinomas. Through these efforts, the MAPK and PI3K signaling cascades have emerged as the main ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Nivolumab Plus Ipilimumab in Thyroid Cancer
 

Status: Recruiting

Condition Summary: Thyroid Cancer

 

Last Updated: 10 Oct 2017

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Last Updated: 19 May 2017

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Trail Evaluating Apatinib With IMRT for Inoperable or Iodine Refractory Thyroid Cancer
 

Status: Recruiting

Condition Summary: Thyroid Cancer

 

Last Updated: 28 Sep 2017

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