Toxic shock syndrome

Common Name(s)

Toxic shock syndrome

Toxic shock syndrome (TSS) is caused by an infection with certain types of bacteria (staphylococcus aureus and group A streptococcus). Toxic shock syndrome has historically affected premenopausal women who use superabsorbent tampons, but can also affect men and children. You have a higher risk of getting toxic shock syndrome if you have an open wound or have had a recent surgery. Symptoms include high fever, low blood pressure, vomiting or diarrhea, rash, and generally feeling ill. Treatment includes antibiotics for the infection and other medications to relieve symptoms. This condition can be very dangerous and requires immediate medical attention.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Toxic shock syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Toxic shock syndrome" returned 283 free, full-text research articles on human participants. First 3 results:

Innate immune responses following Kawasaki disease and toxic shock syndrome.
 

Author(s): Katherine Y H Chen, Nicole Messina, Susie Germano, Rhian Bonnici, Bridget Freyne, Michael Cheung, Greta Goldsmith, Tobias R Kollmann, Michael Levin, David Burgner, Nigel Curtis

Journal:

 

The pathogenesis of Kawasaki disease (KD) remains unknown and there is accumulating evidence for the importance of the innate immune system in initiating and mediating the host inflammatory response. We compared innate immune responses in KD and toxic shock syndrome (TSS) participants ...

Last Updated: 31 Dec 1969

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Streptococcal toxic shock syndrome caused by the dissemination of an invasive emm3/ST15 strain of Streptococcus pyogenes.
 

Author(s): Tsuyoshi Sekizuka, Emina Nai, Tomohiro Yoshida, Shota Endo, Emi Hamajima, Satoka Akiyama, Yoji Ikuta, Natsuko Obana, Takahiro Kawaguchi, Kenta Hayashi, Masahiro Noda, Tomoko Sumita, Masayuki Kokaji, Tatsuo Katori, Masanori Hashino, Kunihiro Oba, Makoto Kuroda

Journal:

 

Streptococcus pyogenes (group A Streptococcus [GAS]) is a major human pathogen that causes a wide spectrum of clinical manifestations. Although invasive GAS (iGAS) infections are relatively uncommon, emm3/ST15 GAS is a highly virulent, invasive, and pathogenic strain. Global molecular ...

Last Updated: 31 Dec 1969

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[Staphylococcal toxic shock syndrome at a chronic hemodialysis].
 

Author(s): Hassan Alaoui, Ayoub Belhadj, Younes Aissaoui, Rachid Seddiki, Mohamed Zoubir, Mohamed Bougalem

Journal:

 

Staphylococcal toxic shock syndrome is an acute and systemic infectious syndrome associated with the super-antigenic activity of staphylococcal toxins. It is a pathology that is rather rare but remains burdened with a considerable mortality despite the therapeutic management. The ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Toxic shock syndrome" returned 24 free, full-text review articles on human participants. First 3 results:

[Gram positive toxic shock syndrome].
 

Author(s): Mélanie C Huser, Claudine Meindl-Fridez, Annelies S Zinkernagel

Journal: Praxis (Bern 1994). 2014 Oct;103(22):1293-9; quiz 1300-1.

 

Last Updated: 31 Dec 1969

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Streptococcal toxic shock syndrome following total thyroidectomy.
 

Author(s): J A Z Hung, P Rajeev

Journal: Ann R Coll Surg Engl. 2013 Oct;95(7):457-60.

 

Group A streptococcal toxic shock syndrome following clean surgery is a rare occurrence. Its incidence following thyroid surgery has not been described in the literature. We report on the presentation and management of severe streptococcal toxic shock syndrome following a total thyroidectomy ...

Last Updated: 31 Dec 1969

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A fatal case of streptococcal toxic shock syndrome due to Streptococcus dysgalactiae subsp. equisimilis possibly caused by an intramuscular injection.
 

Author(s): Hideharu Hagiya, Shunji Okita, Yasutoshi Kuroe, Hiroyoshi Nojima, Shinkichi Otani, Junichi Sugiyama, Hiromichi Naito, Susumu Kawanishi, Shingo Hagioka, Naoki Morimoto

Journal: Intern. Med.. 2013 ;52(3):397-402.

 

An 88-year-old man died of streptococcal toxic shock syndrome due to a group G streptococcus infection that was possibly caused by an intramuscular injection given 30 hours earlier in his right deltoid muscle. The causative pathogen was later identified to be Streptococcus dysgalactiae ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Clinical Trial of the BioMed rTSST‐1 Variant Vaccine in Healthy Adults
 

Status: Recruiting

Condition Summary: Toxic Shock Syndrome

 

Last Updated: 9 Jul 2018

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Effectiveness of Intravenous Immunoglobulins (IVIG) in Toxic Shock Syndromes in Children
 

Status: Not yet recruiting

Condition Summary: Staphylococcal Infection; Streptococcal Infection

 

Last Updated: 23 Feb 2018

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Pediatric Immune Response to Infectious Shock
 

Status: Recruiting

Condition Summary: Severe Pediatric Infectious Shock

 

Last Updated: 8 Aug 2017

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