Trachoma

Common Name(s)

Trachoma

Trachoma is one of the oldest infectious diseases known and is the world’s leading cause of preventable blindness of infectious origin. Trachoma is caused by the bacterium Chlamydia trachomatis and is spread through direct personal contact, shared towels or clothes, flies, and other things that have come in contact with an infected person. Risk factors include water shortage, flies, poor hygiene conditions, and crowded households. When left untreated after years of repeated infections, the inside of the eyelid may be scarred so severely that the eyelid turns inward and the lashes rub on the eyeball, scarring the cornea. This can cause pain, permanent damage to the cornea, and irreversible blindness. Trachoma is prevalent in a majority of the poorest and most remote rural areas of Africa, Asia, Central and South America, Australia, and the Middle East, often affecting women and children.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Trachoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Trachoma" returned 457 free, full-text research articles on human participants. First 3 results:

Baseline trachoma prevalence in Guinea: Results of national trachoma mapping in 31 health districts.
 

Author(s): André Géopogui, Christelly Flore Badila, Mamadou Siradiou Baldé, Cece Nieba, Lamine Lamah, Steven D Reid, Mohamed Lamine Yattara, Jean Jacques Tougoue, Jeremiah Ngondi, Ibrahim Foungotin Bamba, Joseph J Amon, Anthony W Solomon, Yaobi Zhang

Journal:

 

Based on previous studies, historical records and risk factors, trachoma was suspected to be endemic in 31 health districts (HDs) in Guinea. To facilitate planning for the elimination of trachoma as a public health problem, national trachoma surveys were conducted between 2011 and ...

Last Updated: 31 Dec 1969

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Trachoma in Yunnan province of southwestern China: findings from trachoma rapid assessment.
 

Author(s): Min Wu, Zhu Lin Hu, Dan He, Wen Rong Xu, Yan Li

Journal:

 

To understand the situation of active trachoma among children aged 6 to 8 years old and scarring trachoma among those aged 15 and over in Yunnan Province, South-western China.

Last Updated: 31 Dec 1969

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Population-based coverage survey results following the mass drug administration of azithromycin for the treatment of trachoma in Amhara, Ethiopia.
 

Author(s): Tigist Astale, Eshetu Sata, Mulat Zerihun, Andrew W Nute, Aisha E P Stewart, Demelash Gessese, Gedefaw Ayenew, Berhanu Melak, Melsew Chanyalew, Zerihun Tadesse, E Kelly Callahan, Scott D Nash

Journal:

 

Trachoma is the leading infectious cause of blindness worldwide. In communities where the district level prevalence of trachomatous inflammation-follicular among children ages 1-9 years is ≥5%, WHO recommends annual mass drug administration (MDA) of antibiotics with the aim of at ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Trachoma" returned 33 free, full-text review articles on human participants. First 3 results:

Interventions to maximize facial cleanliness and achieve environmental improvement for trachoma elimination: A review of the grey literature.
 

Author(s): Maryann G Delea, Hiwote Solomon, Anthony W Solomon, Matthew C Freeman

Journal:

 

Efforts are underway to scale-up the facial cleanliness and environmental improvement (F&E) components of the World Health Organization's SAFE strategy for elimination of trachoma as a public health problem. Improving understanding of the F&E intervention landscape could inform advancements ...

Last Updated: 31 Dec 1969

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The Relationship between Active Trachoma and Ocular Chlamydia trachomatis Infection before and after Mass Antibiotic Treatment.
 

Author(s): Athumani M Ramadhani, Tamsyn Derrick, David Macleod, Martin J Holland, Matthew J Burton

Journal:

 

Trachoma is a blinding disease, initiated in early childhood by repeated conjunctival infection with the obligate intracellular bacterium Chlamydia trachomatis. The population prevalence of the clinical signs of active trachoma; ''follicular conjunctivitis" (TF) and/or ''intense papillary ...

Last Updated: 31 Dec 1969

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Trachoma.
 

Author(s): Van Charles Lansingh

Journal:

 

Active trachoma is caused by chronic infection of the conjunctiva by Chlamydia trachomatis, and is the world's leading infectious cause of blindness. Infection can lead to: scarring of the tarsal conjunctiva; inversion of the eyelashes (trichiasis), so that they abrade the cornea; ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Trachoma Elimination Study by Focused Antibiotic (TESFA)
 

Status: Not yet recruiting

Condition Summary: Trachoma

 

Last Updated: 4 Jun 2018

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Sanitation, Water, and Instruction in Face-washing for Trachoma
 

Status: Recruiting

Condition Summary: Trachoma

 

Last Updated: 13 Feb 2017

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Kebele Elimination of Trachoma for Ocular Health
 

Status: Not yet recruiting

Condition Summary: Trachoma

 

Last Updated: 11 Apr 2018

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