Trachoma

Common Name(s)

Trachoma

Trachoma is one of the oldest infectious diseases known and is the world’s leading cause of preventable blindness of infectious origin. Trachoma is caused by the bacterium Chlamydia trachomatis and is spread through direct personal contact, shared towels or clothes, flies, and other things that have come in contact with an infected person. Risk factors include water shortage, flies, poor hygiene conditions, and crowded households. When left untreated after years of repeated infections, the inside of the eyelid may be scarred so severely that the eyelid turns inward and the lashes rub on the eyeball, scarring the cornea. This can cause pain, permanent damage to the cornea, and irreversible blindness. Trachoma is prevalent in a majority of the poorest and most remote rural areas of Africa, Asia, Central and South America, Australia, and the Middle East, often affecting women and children.

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Trachoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Trachoma" returned 420 free, full-text research articles on human participants. First 3 results:

The cost of mapping trachoma: Data from the Global Trachoma Mapping Project.
 

Author(s): Guillaume Trotignon, Ellen Jones, Thomas Engels, Elena Schmidt, Deborah A McFarland, Colin K Macleod, Khaled Amer, Amadou A Bio, Ana Bakhtiari, Sarah Bovill, Amy H Doherty, Asad Aslam Khan, Mariamo Mbofana, Siobhain McCullagh, Tom Millar, Consity Mwale, Lisa A Rotondo, Angela Weaver, Rebecca Willis, Anthony W Solomon

Journal:

 

The Global Trachoma Mapping Project (GTMP) was implemented with the aim of completing the baseline map of trachoma globally. Over 2.6 million people were examined in 1,546 districts across 29 countries between December 2012 and January 2016. The aim of the analysis was to estimate ...

Last Updated: 18 Oct 2017

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Prevalence of signs of trachoma, ocular Chlamydia trachomatis infection and antibodies to Pgp3 in residents of Kiritimati Island, Kiribati.
 

Author(s): Anaseini Cama, Andreas Müller, Raebwebwe Taoaba, Robert M R Butcher, Iakoba Itibita, Stephanie J Migchelsen, Tokoriri Kiauea, Harry Pickering, Rebecca Willis, Chrissy H Roberts, Ana Bakhtiari, Richard T Le Mesurier, Neal D E Alexander, Diana L Martin, Rabebe Tekeraoi, Anthony W Solomon,

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In some Pacific Island countries, such as Solomon Islands and Fiji, active trachoma is common, but ocular Chlamydia trachomatis (Ct) infection and trachomatous trichiasis (TT) are rare. On Tarawa, the most populous Kiribati island, both the active trachoma sign "trachomatous inflammation-follicular" ...

Last Updated: 12 Sep 2017

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Use of validated community-based trachoma trichiasis (TT) case finders to measure the total backlog and detect when elimination threshold is achieved: a TT methodology paper.
 

Author(s): Jefitha Karimurio, Hillary Rono, Doris Njomo, John Sironka, Catherine Kareko, Michael Gichangi, Ernest Barasa, Alice Mwangi, Kefa Ronald, Francis Kiio

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The World Health Organization recommends TT surveys to be conducted in adults aged 15+ years (TT 15 survey) and certifies elimination of TT as a public health problem when there is less than 1 unknown case per 1,000 people of all ages. There is no standard survey method to accurately ...

Last Updated: 18 Aug 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Trachoma" returned 31 free, full-text review articles on human participants. First 3 results:

The Relationship between Active Trachoma and Ocular Chlamydia trachomatis Infection before and after Mass Antibiotic Treatment.
 

Author(s): Athumani M Ramadhani, Tamsyn Derrick, David Macleod, Martin J Holland, Matthew J Burton

Journal:

 

Trachoma is a blinding disease, initiated in early childhood by repeated conjunctival infection with the obligate intracellular bacterium Chlamydia trachomatis. The population prevalence of the clinical signs of active trachoma; ''follicular conjunctivitis" (TF) and/or ''intense papillary ...

Last Updated: 26 Oct 2016

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Historical Aspects of Endemic Trachoma in Peru: 1895-2000.
 

Author(s): Vicente Maco, Mayling Encalada, Carlos Wong, Luis A Marcos

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Last Updated: 15 Jan 2016

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Trachoma and Yaws: Common Ground?
 

Author(s): Anthony W Solomon, Michael Marks, Diana L Martin, Alexei Mikhailov, Rebecca M Flueckiger, Oriol Mitjà, Kingsley Asiedu, Jean Jannin, Dirk Engels, David C W Mabey

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Last Updated: 4 Dec 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Sanitation, Water, and Instruction in Face-washing for Trachoma
 

Status: Recruiting

Condition Summary: Trachoma

 

Last Updated: 13 Feb 2017

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Kebele Elimination of Trachoma for Ocular Health
 

Status: Not yet recruiting

Condition Summary: Trachoma

 

Last Updated: 7 Nov 2017

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Mortality Reduction After Oral Azithromycin: Morbidity Study
 

Status: Recruiting

Condition Summary: Childhood Mortality

 

Last Updated: 2 Nov 2017

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