Traumatic brain injury

Common Name(s)

Traumatic brain injury

Traumatic brain injury (TBI) is caused by a blow to the head or jolt to the head or body. It can also be caused by an object going through the skull, like a bullet or even a shattered piece of the skull bone.

Mild TBI is commonly known as a concussion. Common concussion symptoms include a loss of consciousness, being in a confused or dazed state, and headaches. More physical issues may include: sleep issues (either sleeping too much or difficultly sleeping), nausea, or dizziness. People with concussions also experience problems with their senses, memory and concentration. All of these symptoms are also present in more severe brain trauma. However, for severe cases, additional physical symptoms may include seizures, long lasting nausea or vomiting, widened (dilated) pupils, not being able to wake up, or loss of coordination. Other mental symptoms include confusion, slurred speech, and unusual behavior. Babies with brain trauma may experience changes in eating/nursing and persistent crying.

If you recently experienced a fall, car/motorcycle accident, violence, or a sports injury, it is possible that you have a TBI. People are most likely to have a traumatic brain injury between the ages 0-4, 15-24, and 75+.

Doctors can diagnose brain trauma by testing a person’s ability to follow direction and their ability to control different body parts (Glasgow Coma Scale). Brain scans, such as CT scans or MRIs, may also be taken so that the doctor can see if the brain or skull is damaged. Mild brain trauma may be treated by resting and over-the-counter pain medication. However, more severe traumas may require prescribed medication, surgery, or rehabilitation. Individuals with brain trauma will not have all the listed symptoms. If you or your child has been diagnosed with TBI, talk to your doctor and specialists about current treatment options. Support groups are a good resource of information especially for those with more severe TBI.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Traumatic brain injury" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Traumatic brain injury" returned 1926 free, full-text research articles on human participants. First 3 results:

Evaluation of novel computerized tomography scoring systems in human traumatic brain injury: An observational, multicenter study.
 

Author(s): Eric Peter Thelin, David W Nelson, Juho Vehviläinen, Harriet Nyström, Riku Kivisaari, Jari Siironen, Mikael Svensson, Markus B Skrifvars, Bo-Michael Bellander, Rahul Raj

Journal:

 

Traumatic brain injury (TBI) is a major contributor to morbidity and mortality. Computerized tomography (CT) scanning of the brain is essential for diagnostic screening of intracranial injuries in need of neurosurgical intervention, but may also provide information concerning patient ...

Last Updated: 3 Aug 2017

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Successful ceftazidime-avibactam treatment of MDR-KPC-positive Klebsiella pneumoniae infection in a patient with traumatic brain injury: A case report.
 

Author(s): Agnese Gugliandolo, Carla Caio, Maria Lina Mezzatesta, Carmela Rifici, Placido Bramanti, Stefania Stefani, Emanuela Mazzon

Journal: Medicine (Baltimore). 2017 Aug;96(31):e7664.

 

Carbapenem-resistant Enterobacteriaceae infections are a serious health care problem, because of the high mortality. Carbapenem resistance is mainly caused by carbapenemases production, including Klebsiella pneumoniae carbapenemase (KPC). Ceftazidime-avibactam is a new cephalosporin/β-lactamase ...

Last Updated: 2 Aug 2017

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Temporal profile of intracranial pressure and cerebrovascular reactivity in severe traumatic brain injury and association with fatal outcome: An observational study.
 

Author(s): Hadie Adams, Joseph Donnelly, Marek Czosnyka, Angelos G Kolias, Adel Helmy, David K Menon, Peter Smielewski, Peter J Hutchinson

Journal:

 

Both intracranial pressure (ICP) and the cerebrovascular pressure reactivity represent the dysregulation of pathways directly involved in traumatic brain injury (TBI) pathogenesis and have been used to inform clinical management. However, how these parameters evolve over time following ...

Last Updated: 25 Jul 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Traumatic brain injury" returned 370 free, full-text review articles on human participants. First 3 results:

Mild Traumatic Brain Injury (mTBI) and chronic cognitive impairment: A scoping review.
 

Author(s): Kerry McInnes, Christopher L Friesen, Diane E MacKenzie, David A Westwood, Shaun G Boe

Journal:

 

Mild traumatic brain injury (mTBI), or concussion, is the most common type of traumatic brain injury. With mTBI comes symptoms that include headaches, fatigue, depression, anxiety and irritability, as well as impaired cognitive function. Symptom resolution is thought to occur within ...

Last Updated: 11 Apr 2017

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Health State Preference Weights for the Glasgow Outcome Scale Following Traumatic Brain Injury: A Systematic Review and Mapping Study.
 

Author(s): Gordon Ward Fuller, Monica Hernandez, David Pallot, Fiona Lecky, Mathew Stevenson, Belinda Gabbe

Journal: Value Health. 2017 Jan;20(1):141-151.

 

Valid and relevant estimates of health state preference weights (HSPWs) for Glasgow Outcome Scale (GOS) categories are a key input of economic models evaluating treatments for traumatic brain injury (TBI).

Last Updated: 18 Feb 2017

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Progress of Research on Diffuse Axonal Injury after Traumatic Brain Injury.
 

Author(s): Junwei Ma, Kai Zhang, Zhimin Wang, Gang Chen

Journal: Neural Plast.. 2016 ;2016():9746313.

 

The current work reviews the concept, pathological mechanism, and process of diagnosing of DAI. The pathological mechanism underlying DAI is complicated, including axonal breakage caused by axonal retraction balls, discontinued protein transport along the axonal axis, calcium influx, ...

Last Updated: 12 Jan 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 26 May 2017

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Long Term Effects of Erythropoietin in Patients With Moderate to Severe Traumatic Brain Injury
 

Status: Recruiting

Condition Summary: Traumatic Brain Injury

 

Last Updated: 17 Aug 2017

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Last Updated: 26 Sep 2016

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