Truncus Arteriosus

Common Name(s)

Truncus Arteriosus

Truncus Arteriosus is a rare birth defect that affects the heart. People with this condition have one large blood vessel exiting the heart, instead of two separate vessels. Normally, the heart is separated into four chambers, two lower and two upper. However, people with truncus arteriosus are missing part of the wall that divides the two lower chambers. This results in oxygen-poor and oxygen-rich blood mixing in the lower chambers where they would not normally mix. Symptoms usually develop within the first few weeks of life, and may include: blue coloring of the skin, poor feeding, tiredness, poor growth, shortness of breath or rapid breathing, irregular heartbeats, and excessive sweating. A child should receive urgent care if they exhibit rapid, shallow or labored breathing, worsening of blue coloring, or loss of consciousness. A doctor can diagnose this condition using a heart test or an X-ray. Without treatment, truncus arteriosus can be fatal, but surgery to repair the defects is usually successful.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Truncus Arteriosus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Truncus Arteriosus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Truncus Arteriosus" returned 70 free, full-text research articles on human participants. First 3 results:

Repair of truncus arteriosus with interrupted aortic arch (Van Praagh type A4).
 

Author(s): Karl Reyes, Mohsen Ahmed, Alan Brock, Mark Bleiweis

Journal:

 

Truncus arteriosus is an extremely rare and complex form of congenital heart disease. Surgical strategies vary depending on anatomic subtype.  In this tutorial, we present our surgical technique for single stage repair of a truncus arteriosus with interrupted aortic arch (Van Praagh type A4).

Last Updated: 31 Dec 1969

Go To URL
TBX20 loss-of-function mutation responsible for familial tetralogy of Fallot or sporadic persistent truncus arteriosus.
 

Author(s): Ri-Tai Huang, Juan Wang, Song Xue, Xing-Biao Qiu, Hong-Yu Shi, Ruo-Gu Li, Xin-Kai Qu, Xiao-Xiao Yang, Hua Liu, Ning Li, Yan-Jie Li, Ying-Jia Xu, Yi-Qing Yang

Journal:

 

Congenital heart disease (CHD), the most common form of developmental abnormality in humans, remains a leading cause of morbidity and mortality in neonates. Genetic defects have been recognized as the predominant causes of CHD. Nevertheless, CHD is of substantial genetic heterogeneity ...

Last Updated: 31 Dec 1969

Go To URL
Surgical correction of persistent truncus arteriosus on a 33-year-old male with unilateral pulmonary hypertension from migration of pulmonary artery band.
 

Author(s): Wen Ruan, Yee Jim Loh, Kenneth Wei Qiang Guo, Ju Le Tan

Journal:

 

Persistent truncus arteriosus is a rare congenital condition with which survival into adulthood is dismal without surgery. This is the oldest patient reported to our knowledge demonstrating the feasibility of assessing operability in persistent truncus arteriosus with unilateral pulmonary ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Truncus Arteriosus" returned 1 free, full-text review articles on human participants. First 3 results:

46,XY disorders of sex development and congenital diaphragmatic hernia: a case with dysmorphic facies, truncus arteriosus, bifid thymus, gut malrotation, rhizomelia, and adactyly.
 

Author(s): Edward D Esplin, Hassan Chaib, Michael Haney, Brock Martin, Margaret Homeyer, Alexander E Urban, Jonathan A Bernstein

Journal: Am. J. Med. Genet. A. 2015 Jun;167(6):1360-4.

 

The association of 46,XY disorder of sex development (DSD) with congenital diaphragmatic hernia (CDH) is rare, but has been previously described with and without other congenital anomalies. Literature review identified five cases of 46,XY DSD associated with CDH and other congenital ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
 

Status: Recruiting

Condition Summary: Complex Congenital Heart Defect; Dysfunctional RVOT Conduits or Previously Implanted Valve in the Pulmonic Position

 

Last Updated: 16 Mar 2018

Go to URL