Typhus

Common Name(s)

Typhus

Typhus is a general term for a group of diseases passed on by lice, flea, tick, and other insect bites. Types of typhus include epidemic typhus, scrub typhus, murine typhus. Common symptoms of most typhus cases include fever, headache, muscle aches, rapid breathing, and rash. Typhus is uncommon in the United States and can be prevented by avoiding contact with rats and keeping pets treated for ticks and fleas. Usually typhus can be cured with antibiotics.

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Condition Specific Organizations

Following organizations serve the condition "Typhus" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Typhus" returned 449 free, full-text research articles on human participants. First 3 results:

Antinuclear antibodies in scrub typhus: Transient occurrence during acute illness.
 

Author(s): Maria Koshy, John Mathew, Reginald Alex, John Antony Jude, Ravikar Ralph, Thambu David Sudarsanam, Sowmya Sathyendra, J Visalakshi, John Victor Peter

Journal: J Vector Borne Dis. ;55(1):52-57.

 

The pathological hallmark of scrub typhus infection is focal or disseminated vasculitis. As with other infections, antinuclear antibodies (ANA) have been previously described in scrub typhus. However, the underlying mechanisms and implications of this immunological phenomenon is not ...

Last Updated: 31 Dec 1969

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Clinical profile and risk factors associated with severe scrub typhus infection among non-ICU patients in semi-urban south India.
 

Author(s): Sarah S Premraj, K Mayilananthi, Durga Krishnan, K Padmanabhan, D Rajasekaran

Journal: J Vector Borne Dis. ;55(1):47-51.

 

Scrub typhus is as an emerging infectious disease that generally causes acute febrile illness, with disease spectrum ranging from mild illness to multiorgan dysfunction. This study was aimed to report the clinical profile, complications and risk factors associated with severe illness ...

Last Updated: 31 Dec 1969

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Diagnostic performance of serological tests to detect antibodies against acute scrub typhus infection in central India.
 

Author(s): Kiran Pote, Rahul Narang, Pradeep Deshmukh

Journal: Indian J Med Microbiol. ;36(1):108-112.

 

Differentiating scrub typhus from other acute febrile illness is difficult due to non specificity of clinical symptoms and relative absence of eschar in Indian population. The diagnosis thus relies mainly on laboratory tests. Antibody based serological tests are mainstay of scrub ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Typhus" returned 25 free, full-text review articles on human participants. First 3 results:

Scrub typhus point-of-care testing: A systematic review and meta-analysis.
 

Author(s): Kartika Saraswati, Nicholas P J Day, Mavuto Mukaka, Stuart D Blacksell

Journal:

 

Diagnosing scrub typhus clinically is difficult, hence laboratory tests play a very important role in diagnosis. As performing sophisticated laboratory tests in resource-limited settings is not feasible, accurate point-of-care testing (POCT) for scrub typhus diagnosis would be invaluable ...

Last Updated: 31 Dec 1969

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A review of the global epidemiology of scrub typhus.
 

Author(s): Guang Xu, David H Walker, Daniel Jupiter, Peter C Melby, Christine M Arcari

Journal:

 

Scrub typhus is a serious public health problem in the Asia-Pacific area. It threatens one billion people globally, and causes illness in one million people each year. Caused by Orientia tsutsugamushi, scrub typhus can result in severe multiorgan failure with a case fatality rate ...

Last Updated: 31 Dec 1969

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Estimating the burden of scrub typhus: A systematic review.
 

Author(s): Ana Bonell, Yoel Lubell, Paul N Newton, John A Crump, Daniel H Paris

Journal:

 

Scrub typhus is a vector-borne zoonotic disease that can be life-threatening. There are no licensed vaccines, or vector control efforts in place. Despite increasing awareness in endemic regions, the public health burden and global distribution of scrub typhus remains poorly known.

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Scrub Typhus Antibiotic Resistance Trial
 

Status: Recruiting

Condition Summary: Scrub Typhus

 

Last Updated: 12 Dec 2017

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Scrub Typhus RDT Study
 

Status: Recruiting

Condition Summary: The Prevalence of Scrub Typhus

 

Last Updated: 5 Jan 2018

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Eschar Investigations in Scrub Typhus
 

Status: Recruiting

Condition Summary: Scrub Typhus

 

Last Updated: 14 Aug 2018

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