Urachal cancer

Common Name(s)

Urachal cancer

Urachal cancer is a rare type of bladder cancer, making up less than 1% of all bladder cancers. Only about 350 cases have been described in the medical literature to date. The urachus is a primitive structure which before birth connected the bellybutton and the bladder. This connection normally disappears before birth, but in some people remains.   Urachal cancers are classified as such based on location at the dome or anterior wall of the bladder and discovery of remnants of the urachus. Most urachal cancers are adenocarcinomas (cancers that develop from gland cells). Others may be sarcomas (which develop from connective tissue - such as leiomyosarcoma, rhabdomyosarcoma, and malignant fibrous histiocytoma), small cell carcinomas, transitional cell cancer, and mixed neoplasias. Most individuals with urachal cancer present with hematuria (blood in urine). Other symptoms may include abdominal pain, a palpable abdominal mass, mucinuria, and bacteriuria.  Patients who present with early disease confined to the urachus have a good prognosis when treated with partial cystectomy, umbilicotomy, and urachal resection. The prognosis for those with advanced disease is less promising.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Urachal cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Urachal cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Urachal cancer" returned 5 free, full-text research articles on human participants. First 3 results:

Prognostic factors for urachal cancer: a bayesian model-averaging approach.
 

Author(s): In Kyong Kim, Joo Yong Lee, Jong Kyou Kwon, Jae Joon Park, Kang Su Cho, Won Sik Ham, Sung Joon Hong, Seung Choul Yang, Young Deuk Choi

Journal: Korean J Urol. 2014 Sep;55(9):574-80.

 

This study was conducted to evaluate prognostic factors and cancer-specific survival (CSS) in a cohort of 41 patients with urachal carcinoma by use of a Bayesian model-averaging approach.

Last Updated: 19 Sep 2014

Go To URL
Urachal cancer with direct caecal invasion: differential diagnosis from primary colon cancer.
 

Author(s): Ji Young Park, Tae Joo Jeon, Mi Jin Ryu, Won Chang Shin

Journal:

 

A 56-year-old man who had a history of repeated previous treatment for cystitis was admitted with abdominal distension, dysuria, pollakiuria, nocturia and sensation of urine retention after emptying the bladder. A CT scan showed a 10 cm irregularly shaped soft tissue mass abutting ...

Last Updated: 6 Jun 2014

Go To URL
Laparoscopic partial cystectomy for urachal and bladder cancer.
 

Author(s): Jose R Colombo Jr, Mihir Desai, David Canes, Rodrigo Frota, Georges-Pascal Haber, Alireza Moinzadeh, Ingolf Tuerk, Mahesh R Desai, Inderbir S Gill

Journal: Clinics (Sao Paulo). 2008 Dec;63(6):731-4.

 

To report our initial experiences with laparoscopic partial cystectomy for urachal and bladder malignancy.

Last Updated: 8 Dec 2008

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Urachal cancer" returned 1 free, full-text review articles on human participants. First 3 results:

Urachal cancer: contemporary review of the pathological, surgical, and prognostic aspects of this rare disease.
 

Author(s): Mark A Behrendt, Jeroen DE Jong, Bas W VAN Rhijn

Journal: Minerva Urol Nefrol. 2016 Apr;68(2):172-84.

 

Surgery is the mainstay of treatment for patients with urachal cancer (UraC). Still, one third of patients are un-resectable at presentation. Histology shows adenocarcinomas in the majority of cases with resemblance to enteric tumors. Standard chemotherapeutic regimens for bladder ...

Last Updated: 9 Jun 2016

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.