Uveal melanoma

Common Name(s)

Uveal melanoma

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Uveal melanoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Uveal melanoma" returned 448 free, full-text research articles on human participants. First 3 results:

Punctuated evolution of canonical genomic aberrations in uveal melanoma.
 

Author(s): Matthew G Field, Michael A Durante, Hima Anbunathan, Louis Z Cai, Christina L Decatur, Anne M Bowcock, Stefan Kurtenbach, J William Harbour

Journal:

 

Cancer is thought to arise through the accumulation of genomic aberrations evolving under Darwinian selection. However, it remains unclear when the aberrations associated with metastasis emerge during tumor evolution. Uveal melanoma (UM) is the most common primary eye cancer and frequently ...

Last Updated: 31 Dec 1969

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High expression of lncRNA PVT1 independently predicts poor overall survival in patients with primary uveal melanoma.
 

Author(s): Haiming Xu, Jingwen Gong, Hui Liu

Journal:

 

The plasmacytoma variant translocation 1 gene (PVT1) plays an oncogenic role in the initiation and progression of multiple cancers. In this study, by using deep-sequencing data and follow-up data in the Cancer Genome Atlas-Uveal melanomas (TCGA-UVM), we assessed the association between ...

Last Updated: 31 Dec 1969

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Long non-coding RNA FTH1P3 facilitates uveal melanoma cell growth and invasion through miR-224-5p.
 

Author(s): Xiaoli Zheng, Hongwei Tang, Xiaofeng Zhao, Yamei Sun, Yanfang Jiang, Yonghua Liu

Journal:

 

Growing evidences indicated that Long noncoding RNAs (lncRNAs) played important roles in tumor initiation and progression. However, the function and mechnism of lncRNA ferritin heavy chain 1 pseudogene 3 (FTH1P3) remain unknown in uveal melanoma. We showed that the expression level ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Uveal melanoma" returned 49 free, full-text review articles on human participants. First 3 results:

Role of Epigenetics in Uveal Melanoma.
 

Author(s): Yongyun Li, Renbing Jia, Shengfang Ge

Journal:

 

Uveal melanoma (UM) is a severe human malignancy with a high mortality rate that demands continued research into new and alternative forms of prevention and treatment. The emerging field of epigenetics is beginning to unfold an era of contemporary approaches to reducing the risk and ...

Last Updated: 31 Dec 1969

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Focus on cutaneous and uveal melanoma specificities.
 

Author(s): Charlotte Pandiani, Guillaume E Béranger, Justine Leclerc, Robert Ballotti, Corine Bertolotto

Journal: Genes Dev.. 2017 04;31(8):724-743.

 

Cutaneous melanoma (CM) and uveal melanoma (UM) derive from cutaneous and uveal melanocytes that share the same embryonic origin and display the same cellular function. However, the etiopathogenesis and biological behaviors of these melanomas are very different. CM and UM display ...

Last Updated: 31 Dec 1969

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Uveal Melanoma Treatment and Prognostication.
 

Author(s): Mehmet Dogrusöz, Martine J Jager, Bertil Damato

Journal: Asia Pac J Ophthalmol (Phila). ;6(2):186-196.

 

Approximately 90% of uveal melanoma develop in the choroid, with the remainder arising in the ciliary body or the iris. The treatment of uveal melanoma is aimed at conserving the eye and useful vision, and, if possible, preventing metastatic disease. Enucleation is now reserved for ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Phase II Study of BVD-523 in Metastatic Uveal Melanoma
 

Status: Recruiting

Condition Summary: Uveal Melanoma

 

Last Updated: 29 Mar 2018

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Vorinostat in Patients With Class 2 High Risk Uveal Melanoma
 

Status: Not yet recruiting

Condition Summary: Uveal Melanoma

 

Last Updated: 18 May 2018

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Dendritic Cells Plus Autologous Tumor RNA in Uveal Melanoma
 

Status: Recruiting

Condition Summary: Uveal Melanoma

 

Last Updated: 14 Jun 2018

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