Vancomycin-resistant enterococci

Common Name(s)

Vancomycin-resistant enterococci, VRE, Enterococcus species resistant to vancomycin

VRE (Vancomycin-resistant Enterococcus) is an infection caused by the bacteria Enterococcus which has become resistant to treatment with vancomycin, an antibiotic commonly used to treat this type of infection. Enterococcus is a type of bacteria that is normally found in human intestines (gut) and the female genital tract and is also often found in the environment without causing disease. When it becomes resistant to vancomycin, it is then called vancomycin resistant Enterococcus or VRE. VRE can be present in an individual but not cause symptoms, this is often called colonization of the bacteria. Sometimes however, the VRE bacteria can cause a variety of infections in the urinary tract, the bloodstream or in open wounds on the skin. VRE is spread by simple skin to skin contact or by touching surfaces contaminated with the bacteria. Most VRE infections spread this way in hospitals. VRE cannot be spread through the air by coughing or sneezing. People at risk for VRE infections include those who have been previously treated with vancomycin or have had other long term antibiotic use, people with weakened immune systems especially in the hospital setting, surgical patients, or people with urinary catheters or intravenous tubing placed (IV) as these allow an opening for the bacteria to enter the body.

To avoid the spread of VRE, wash hands frequently and hospital workers or care givers should wear gown and gloves when treating an infected person. Individuals with colonized bacteria (no symptoms) do not need to be treated. Most VRE infections can be treated with antibiotics other than vancomycin. Lab tests can determine which antibiotics may work best. If you think you may have VRE or may have been exposed, speak with your doctor. If you have been diagnosed with VRE, talk with your doctor or specialist about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vancomycin-resistant enterococci" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Vancomycin-resistant enterococci" returned 222 free, full-text research articles on human participants. First 3 results:

Point-prevalence survey of carbapenemase-producing Enterobacteriaceae and vancomycin-resistant enterococci in adult inpatients in a university teaching hospital in the UK.
 

Author(s): H J Wilson, F Khokhar, D A Enoch, N M Brown, J Ahluwalia, G Dougan, M E Török

Journal: J. Hosp. Infect.. 2018 Sep;100(1):35-39.

 

Infections with carbapenemase-producing Enterobacteriaceae (CPE) and vancomycin-resistant enterococci (VRE) are associated with increased morbidity and mortality, but the carriage rates of CRE and VRE among hospital inpatients are unknown. A point-prevalence survey was conducted to ...

Last Updated: 31 Dec 1969

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A novel high-resolution melting analysis approach for rapid detection of vancomycin-resistant enterococci.
 

Author(s): Hani Adnan Ozbak

Journal: Ann Saudi Med. ;38(3):200-207.

 

Vancomycin-resistant enterococci (VRE) are resistant to most classes of antibiotics. Diagnosis of VRE using standard methods takes 2 to 5 days. Development of a rapid PCR-assay that detects and identifies resistant genes in bacteria would provide time-critical information on the presence ...

Last Updated: 31 Dec 1969

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A novel bacteriocin from Enterococcus faecalis 478 exhibits a potent activity against vancomycin-resistant enterococci.
 

Author(s): Uraporn Phumisantiphong, Kanokrat Siripanichgon, Onrapak Reamtong, Pornphan Diraphat

Journal:

 

The emergence of multidrug-resistant enterococci (MDRE) and particularly vancomycin-resistant enterococci (VRE) is considered a serious health problem worldwide, causing the need for new antimicrobials. The aim of this study was to discover and characterize bacteriocin against clinical ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Vancomycin-resistant enterococci" returned 14 free, full-text review articles on human participants. First 3 results:

Incidence and Outcomes Associated With Infections Caused by Vancomycin-Resistant Enterococci in the United States: Systematic Literature Review and Meta-Analysis.
 

Author(s): Hsiu-Yin Chiang, Eli N Perencevich, Rajeshwari Nair, Richard E Nelson, Matthew Samore, Karim Khader, Margaret L Chorazy, Loreen A Herwaldt, Amy Blevins, Melissa A Ward, Marin L Schweizer

Journal: Infect Control Hosp Epidemiol. 2017 02;38(2):203-215.

 

BACKGROUND Information about the health and economic impact of infections caused by vancomycin-resistant enterococci (VRE) can inform investments in infection prevention and development of novel therapeutics. OBJECTIVE To systematically review the incidence of VRE infection in the ...

Last Updated: 31 Dec 1969

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Daptomycin for the treatment of bacteraemia due to vancomycin-resistant enterococci.
 

Author(s): Jose M Munita, Barbara E Murray, Cesar A Arias

Journal: Int. J. Antimicrob. Agents. 2014 Nov;44(5):387-95.

 

Treatment of severe infections caused by vancomycin-resistant enterococci (VRE) is challenging due to the scarcity of reliable therapeutic alternatives. In this context, daptomycin (DAP), a lipopeptide antibiotic, has emerged as an interesting alternative as it is one of the few compounds ...

Last Updated: 31 Dec 1969

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Central nervous system infections due to vancomycin-resistant enterococci: case series and review of the literature.
 

Author(s): Jeffrey S Wang, Katie Muzevich, Michael B Edmond, Gonzalo Bearman, Michael P Stevens

Journal: Int. J. Infect. Dis.. 2014 Aug;25():26-31.

 

To evaluate reported cases of central nervous system (CNS) infections due to vancomycin-resistant enterococci (VRE) and describe the data necessary to better understand clinical characteristics of this rare disease process.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Trial of Encapsulated Fecal Microbiota for Vancomycin Resistant Enterococcus Decolonization
 

Status: Recruiting

Condition Summary: Antibiotic Resistant Strain

 

Last Updated: 27 Jun 2018

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Antibiotic Stewardship and Infection Control in Patients at High Risk of Developing Infection by Clostridium Difficile, Vancomycin-Resistant Enterococci or Multi-Resistant Gram-Negatives
 

Status: Recruiting

Condition Summary: Clostridium Difficile Infection; VRE Infection; Nosocomial Infection; MRGN Bacteria

 

Last Updated: 15 Oct 2018

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Fecal Microbiota Transplantation for CRE/VRE
 

Status: Recruiting

Condition Summary: Antimicrobial Resistance; Colonization

 

Last Updated: 25 Mar 2018

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