Valvular heart disease

Common Name(s)

Valvular heart disease

Valvular heart disease refers to diseases that affect any of the four heart valves. Of the four heart valves, two are on the right, the pulmonary and tricuspid valves. The other two are on the left; they are the aortic and mitral valves. Valvular heart disease can be present at birth (congenital) or it can be acquired later in life. Blood normally flows in one direction through the valves due to the forces of the heartbeats. With the disease, the valves become hardened, narrow, or are unable to close properly, which can allow blood to travel in the wrong direction or at the wrong time.

Some people with valvular heart disease never have noticeable symptoms. In those that do, symptoms may include a racing or very hard heartbeat (palpitations), fatigue, dizziness, fever, and rapid weight gain. The risk of valvular heart disease increases with age. Most people diagnosed with the disease are older than 50, and many are older than 75. Acquired valvular heart disease is often caused by another disease or infection; the most common causes are rheumatic fever and endocarditis. Other risk factors for the disease include smoking cigarettes, abusing alcohol, being overweight, and uncontrolled blood sugar for people with diabetes.

In order to diagnose the disease, your doctor will perform a physical exam. They may listen to your heartbeat for a swishing sound (a murmur). The doctor may also suggest tests to confirm the diagnosis such as MRIs or they may try to see into your heart using an angiogram. There are medications available for treatment. However, in more severe cases, surgery to replace the valve may be necessary. If you have been diagnosed with valvular heart disease, talk to your doctor and cardiologist about the most current treatment options. Support organizations are also a good source of information and will help connect you with others living with valvular heart disease.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Valvular heart disease" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Valvular heart disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Valvular heart disease" returned 179 free, full-text research articles on human participants. First 3 results:

Analysis of the microRNA signature in left atrium from patients with valvular heart disease reveals their implications in atrial fibrillation.
 

Author(s): Rosa Doñate Puertas, Audrey Jalabert, Emmanuelle Meugnier, Vanessa Euthine, Philippe Chevalier, Sophie Rome

Journal:

 

Among the potential factors which may contribute to the development and perpetuation of atrial fibrillation, dysregulation of miRNAs has been suggested. Thus in this study, we have quantified the basal expressions of 662 mature human miRNAs in left atrium (LA) from patients undergoing ...

Last Updated: 31 Dec 1969

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Carcinoid heart disease revealed by cyanosis with both right and left valvular involvement: a case report.
 

Author(s): Khadija Khay, Salim Arous, Tarik Bentaoune, Abdenasser Drighil, Rachida Habbal

Journal:

 

Carcinoid heart disease is a frequent complication of carcinoid syndrome. It is related to the release by the carcinoid tumor and/or its metastases of bioactive substances such as serotonin. It is characterized by right-sided valvular involvement and can lead to right-sided heart ...

Last Updated: 31 Dec 1969

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Prevalence and Outcomes of Left-Sided Valvular Heart Disease Associated With Chronic Kidney Disease.
 

Author(s): Zainab Samad, Joseph A Sivak, Matthew Phelan, Phillip J Schulte, Uptal Patel, Eric J Velazquez

Journal:

 

Chronic kidney disease (CKD) is an adverse prognostic marker for valve intervention patients; however, the prevalence and related outcomes of valvular heart disease in CKD patients is unknown.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Valvular heart disease" returned 77 free, full-text review articles on human participants. First 3 results:

Management of tricuspid valve regurgitation: Position statement of the European Society of Cardiology Working Groups of Cardiovascular Surgery and Valvular Heart Disease.
 

Author(s): Manuel J Antunes, José Rodríguez-Palomares, Bernard Prendergast, Michele De Bonis, Raphael Rosenhek, Nawwar Al-Attar, Fabio Barili, Filip Casselman, Thierry Folliguet, Bernard Iung, Patrizio Lancellotti, Claudio Muneretto, Jean-François Obadia, Luc Pierard, Piotr Suwalski, Pepe Zamorano,

Journal: Eur J Cardiothorac Surg. 2017 Dec;52(6):1022-1030.

 

Tricuspid regurgitation (TR) is a very frequent manifestation of valvular heart disease. It may be due to the primary involvement of the valve or secondary to pulmonary hypertension or to the left-sided heart valve disease (most commonly rheumatic and involving the mitral valve). ...

Last Updated: 31 Dec 1969

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Palliative care in end-stage valvular heart disease.
 

Author(s): Jill M Steiner, Stephanie Cooper, James N Kirkpatrick

Journal: Heart. 2017 08;103(16):1233-1237.

 

Valvular heart disease (VHD), particularly aortic valve disease, is prevalent with increasing incidence. When surgery is not possible, or when risks outweigh benefits, percutaneous treatment options may offer effective alternatives. However, procedures may not always go as planned, ...

Last Updated: 31 Dec 1969

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Effects of Non-Vitamin K Antagonist Oral Anticoagulants Versus Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: A Systematic Review and Meta-Analysis.
 

Author(s): Kuo-Li Pan, Daniel E Singer, Bruce Ovbiagele, Yi-Ling Wu, Mohamed A Ahmed, Meng Lee

Journal:

 

The original non-vitamin K antagonist oral anticoagulant (NOAC) trials in nonvalvular atrial fibrillation (AF) enrolled patients with native valve pathologies. The object of this study was to quantify the benefit-risk profiles of NOACs versus warfarin in AF patients with native valvular ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Valvular Heart Disease Registry
 

Status: Recruiting

Condition Summary: Valvular Heart Disease

 

Last Updated: 4 Apr 2018

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Registration and Cohort Study of Valvular Heart Disease in Adults in China
 

Status: Not yet recruiting

Condition Summary: Valvular Heart Disease

 

Last Updated: 26 Mar 2018

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Valvular Heart Disease Registry Study in Second Affiliated Hospital of ZheJiang University
 

Status: Not yet recruiting

Condition Summary: Valvular Heart Disease

 

Last Updated: 4 Jan 2017

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