Vascular malformations

Common Name(s)

Vascular malformations

Vascular malformations are a type of congenital lesion (a growth present at birth) made up of arteries, veins, capillaries and/or lymphatic vessels. About 3% of children are born with vascular malformations. These malformations are not tumors and are therefore not cancerous. Most of the lesions only cause cosmetic issues, but some can cause difficulties depending on where it forms. Unlike hemangiomas, vascular malformations are present at birth (though it may take a few weeks to even a few years to be noticeable) and grow throughout a person’s lifetime. There are several different types depending on the type of blood vessel involved. Two common types of vascular malformations are salmon patches and port wine stains.

Symptoms vary based on the location of the lesion and the affected type of blood or lymph vessel. Some growths may affect vision or breathing. The causes of most of the lesions are not well understood. Vascular malformations are believed to have a genetic cause and display autosomal dominant inheritance, meaning you only need to inherit one changed gene to cause the condition (genes come in pairs one from each parent). Most of the involved genes are not known at this time, and the change usually happens by chance (sporadic). However, affected individuals will still have a 50% chance of passing it to their children. Locations and sizes of lesions can vary greatly within a family.

In order to diagnose vascular malformations, your doctor will perform a physical exam. Other tests may include imaging tests, including MRIs, CT scans, and ultrasounds. Treatment options may include surgery, laser therapy or injection of medicine into the vessel to make it less visible; however, treatment may not always be necessary. Talk to your doctor(s) about the most current treatment options. Genetic counselors and support groups are also good sources of information and can help connect you with others affected by vascular malformations.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vascular malformations" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Vascular malformations" returned 113 free, full-text research articles on human participants. First 3 results:

A Diagnostic Program of Vascular Tumor and Vascular Malformations in Children According to Modern Classification.
 

Author(s): Iryna Benzar

Journal: Acta Medica (Hradec Kralove). ;60(1):19-26.

 

The aim of the study was to analyze the cohort of inpatient children with vascular anomalies according to the globally accepted classification introduced by the ISSVA.

Last Updated: 27 May 2017

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Does the type and size of Amplatzer vascular plug affect the occlusion time of pulmonary arteriovenous malformations?
 

Author(s): Ahmed Kamel Abdel Aal, Moustafa Omar Massoud, Dina Mahmoud Elantably

Journal: Diagn Interv Radiol. ;23(1):61-65.

 

Occlusion time (OT) is an important factor in the treatment of pulmonary arteriovenous malformations (PAVMs) since it can lead to serious complications. The purpose of our study is to calculate the OT of Amplatzer vascular plug (AVP, St Jude Medical), and correlate it to the type ...

Last Updated: 18 Nov 2016

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Persistence of pulmonary arteriovenous malformations after successful embolotherapy with Amplatzer vascular plug: long-term results.
 

Author(s): Ahmed Kamel Abdel Aal, Rafik Mohamed Ibrahim, Amr Soliman Moustafa, Maysoon Farouk Hamed, Souheil Saddekni

Journal: Diagn Interv Radiol. ;22(4):358-64.

 

We aimed to evaluate the frequency of persistence and complication rates of pulmonary arteriovenous malformations (PAVMs) treated with Amplatzer vascular plug (AVP) or Amplatzer vascular plug type 2 (AVP2).

Last Updated: 12 Jul 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Vascular malformations" returned 28 free, full-text review articles on human participants. First 3 results:

Vascular malformations: an update on imaging and management.
 

Author(s): Sergio Sierre, Darío Teplisky, José Lipsich

Journal: Arch Argent Pediatr. 2016 Apr;114(2):167-76.

 

Vascular malformations comprise a broad and heterogeneous range of lesions that often represent a diagnostic and therapeutic challenge for the pediatrician. For a long time, the use of an inaccurate nomenclature has led to confusion. Since management depends on the specific vascular ...

Last Updated: 15 Apr 2016

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Peripheral limb vascular malformations: an update of appropriate imaging and treatment options of a challenging condition.
 

Author(s): H Madani, J Farrant, N Chhaya, I Anwar, H Marmery, A Platts, B Holloway

Journal: Br J Radiol. 2015 Mar;88(1047):20140406.

 

Peripheral vascular malformations encompass a wide spectrum of lesions that can present as an incidental finding or produce potentially life- or limb-threatening complications. They can have intra-articular and intraosseous extensions that will result in more diverse symptomology ...

Last Updated: 20 Feb 2015

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Epidemiology, diagnostics and treatment of vascular tumours and malformations.
 

Author(s): Piotr Wójcicki, Karolina Wójcicka

Journal: Adv Clin Exp Med. ;23(3):475-84.

 

Vascular tumours and vascular malformations are common vasculose anomalies characteristic for dissimilar clinical course, specific biological as well as immune cytological and histological properties. Vascular lesions classification system and their detailed division into groups and ...

Last Updated: 1 Jul 2014

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Clinical Trial Information This information is provided by ClinicalTrials.gov

suPERficial Slow-flow Vascular malFORMations Treated With sirolimUS
 

Status: Recruiting

Condition Summary: Vascular Malformation

 

Last Updated: 23 Feb 2017

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the Efficiency of Endoscopic Treatment for Recurrent Small Intestinal Bleeding Due to Gastrointestinal Vascular Malformation
 

Status: Recruiting

Condition Summary: Gastrointestinal Vascular Malformation

 

Last Updated: 26 Dec 2016

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the Efficiency of Thalidomide for Recurrent Small Intestinal Bleeding Due to Gastrointestinal Vascular Malformation
 

Status: Recruiting

Condition Summary: Gastrointestinal Vascular Malformation

 

Last Updated: 30 Jul 2016

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