Vasculitis

Common Name(s)

Vasculitis

Vasculitis is redness and swelling (inflammation) of the system of small tubes that carry blood throughout your body (vessels, arteries, veins and capillaries). This inflammation can cause these tubes to become weak and narrow, leading to a blockage which will cut off blood supply to an area of the body. Vasculitis can affect any area of the body, leading to damage of any organ or tissue.

The symptoms of vasculitis vary depending on which organ or tissue is affected. Symptoms may include a rash, muscle weakness, fever, weight loss, general fatigue, kidney failure, heart attack or stroke. Vasculitis can be diagnosed by your doctor using a combination of your health history, physical exam, blood and urine tests to look for signs of inflammation or organ damage, imaging tests (x-ray, CT or MRI) to look for inflammation and organ damage, and removal of a small piece of affected tissue (biopsy) to look for signs of vasculitis.

Treatment options depends on which tissue or organ is affected. In some cases, treatment may not be necessary and the inflammation will go away on its own. Other times, medications may be necessary to prevent further damage and relieve symptoms. If you have been diagnosed with vasculitis, talk with your doctor about the most current treatment options. Support groups are a good resource for additional information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vasculitis" for support, advocacy or research.

Alliance for Cryoglobulinemia

Alliance for Cryoglobulinemia is an inclusive network of patients, caregivers, family, medical professionals and other supporters dedicated to improving quality of life for people with cryoglobulinemia. Our goal is to create a platform that links all efforts of campaigns, research, support and other resources related to cryoglobulinemia. We utilize medical advisors, community networking, crowd-funding, peer to peer support, social media and campaign strategies to advocate awareness, patient support, education and research.

Last Updated: 24 Apr 2015

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Alpha-1 Awareness UK

Alpha-1 Awareness UK is a charity formed to provide information and support to sufferers of alpha-1 antitrypsin deficiency. We maintain close links with experts and organisations associated with the condition, including European Alpha groups, pharmaceuticals and clinicians. Our primary objective is to improve the understanding of A1AT in both patients and medical professionals, as well as to provide support for Alphas and their carers.

Last Updated: 29 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vasculitis" for support, advocacy or research.

Alliance for Cryoglobulinemia

Alliance for Cryoglobulinemia is an inclusive network of patients, caregivers, family, medical professionals and other supporters dedicated to improving quality of life for people with cryoglobulinemia. Our goal is to create a platform that links all efforts of campaigns, research, support and other resources related to cryoglobulinemia. We utilize medical advisors, community networking, crowd-funding, peer to peer support, social media and campaign strategies to advocate awareness, patient support, education and research.

http://allianceforcryo.org/

Last Updated: 24 Apr 2015

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Alpha-1 Awareness UK

Alpha-1 Awareness UK is a charity formed to provide information and support to sufferers of alpha-1 antitrypsin deficiency. We maintain close links with experts and organisations associated with the condition, including European Alpha groups, pharmaceuticals and clinicians. Our primary objective is to improve the understanding of A1AT in both patients and medical professionals, as well as to provide support for Alphas and their carers.

http://www.alpha1awareness.org.uk

Last Updated: 29 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Vasculitis" returned 1503 free, full-text research articles on human participants. First 3 results:

Retinal Vasculitis in Takayasu's Arteritis.
 

Author(s): Priya Bajgai, Ramandeep Singh

Journal: N. Engl. J. Med.. 2018 May;378(21):e28.

 

Last Updated: 31 Dec 1969

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Delta Neutrophil Index Is Associated with Vasculitis Activity and Risk of Relapse in ANCA-Associated Vasculitis.
 

Author(s): Juyoung Yoo, Sung Soo Ahn, Seung Min Jung, Jason Jungsik Song, Yong Beom Park, Sang Won Lee

Journal: Yonsei Med. J.. 2018 May;59(3):397-405.

 

Delta neutrophil index (DNI) represents the immature granulocytes count associated with neutrophil-consumption. We investigated whether DNI might be associated with Birmingham vasculitis activity score (BVAS) at diagnosis and could predict relapse during the follow-up in patients ...

Last Updated: 31 Dec 1969

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Macular changes in retinal vasculitis.
 

Author(s): Kumar Saurabh, Rupak Roy

Journal: Indian J Ophthalmol. 2018 03;66(3):439.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Vasculitis" returned 270 free, full-text review articles on human participants. First 3 results:

Genetics of immunoglobulin-A vasculitis (Henoch-Schönlein purpura): An updated review.
 

Author(s): Raquel López-Mejías, Santos Castañeda, Fernanda Genre, Sara Remuzgo-Martínez, F David Carmona, Javier Llorca, Ricardo Blanco, Javier Martín, Miguel A González-Gay

Journal: Autoimmun Rev. 2018 Mar;17(3):301-315.

 

Immunoglobulin-A vasculitis (IgAV) is classically a childhood small-sized blood vessel vasculitis with predominant involvement of the skin. Gastrointestinal and joint manifestations are common in patients diagnosed with this condition. Nephritis, which is more severe in adults, constitutes ...

Last Updated: 31 Dec 1969

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New insights in the pathogenesis of immunoglobulin A vasculitis (Henoch-Schönlein purpura).
 

Author(s): Marieke H Heineke, Aranka V Ballering, Agnès Jamin, Sanae Ben Mkaddem, Renato C Monteiro, Marjolein Van Egmond

Journal: Autoimmun Rev. 2017 Dec;16(12):1246-1253.

 

Immunoglobulin A vasculitis (IgAV), also referred to as Henoch-Schönlein purpura, is the most common form of childhood vasculitis. The pathogenesis of IgAV is still largely unknown. The disease is characterized by IgA1-immune deposits, complement factors and neutrophil infiltration, ...

Last Updated: 31 Dec 1969

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Settings and artefacts relevant for Doppler ultrasound in large vessel vasculitis.
 

Author(s): L Terslev, A P Diamantopoulos, U Møller Døhn, W A Schmidt, S Torp-Pedersen

Journal:

 

Ultrasound is used increasingly for diagnosing large vessel vasculitis (LVV). The application of Doppler in LVV is very different from in arthritic conditions. This paper aims to explain the most important Doppler parameters, including spectral Doppler, and how the settings differ ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Endothelin Antagonism in ANCA Vasculitis
 

Status: Recruiting

Condition Summary: Vasculitis

 

Last Updated: 25 Oct 2017

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A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis
 

Status: Recruiting

Condition Summary: ANCA-Associated Vasculitis

 

Last Updated: 24 May 2018

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Optical Coherence Tomography (OCT) in Retinal Vasculitis
 

Status: Recruiting

Condition Summary: Retinal Vasculitis

 

Last Updated: 3 Apr 2018

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