Vernal keratoconjunctivitis

Common Name(s)

Vernal keratoconjunctivitis

Vernal keratoconjunctivitis (VKC) is a chronic, severe allergy that affects the surfaces of the eyes. It most commonly occurs in boys living in warm, dry climates. Attacks associated with VKC are common in the spring (hence the name "vernal") and summer but often reoccur in the winter. Signs and symptoms usually begin before 10 years of age and may include hard, cobblestone-like bumps (papillae) on the upper eyelid; sensitivity to light; redness; sticky mucus discharge; and involuntary blinking or spasms of the eyelid (blepharospasm).  The condition usually subsides at the onset of puberty. It is caused by a hypersensitivity (allergic reaction) to airborne-allergens. Management focuses on preventing "flare ups" and relieving the symptoms of the condition.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vernal keratoconjunctivitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Vernal keratoconjunctivitis" returned 71 free, full-text research articles on human participants. First 3 results:

Supratarsal injection of triamcinolone for severe vernal keratoconjunctivitis in children.
 

Author(s): Alexandre Xavier da Costa, José Álvaro Pereira Gomes, Leonardo Guedes Candido Marculino, Vera Lucia Liendo, Telma Pereira Barreiro, Myrna Serapião Dos Santos

Journal: Arq Bras Oftalmol. 2017 Jun;80(3):186-188.

 

To evaluate the use of supratarsal injection of triamcinolone acetonide in severe vernal keratoconjunctivitis (VKC) in children.

Last Updated: 23 Aug 2017

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Tacrolimus eye drops as monotherapy for vernal keratoconjunctivitis: a randomized controlled trial.
 

Author(s): Eduardo Gayger Müller, Myrna Serapião Dos Santos, Denise Freitas, José Álvaro Pereira Gomes, Rubens Belfort

Journal: Arq Bras Oftalmol. 2017 Jun;80(3):154-158.

 

To assess the efficacy of monotherapy using tacrolimus eye drops versus sodium cromoglycate for the treatment of vernal keratoconjunctivitis (VKC).

Last Updated: 23 Aug 2017

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Systematic approach to managing vernal keratoconjunctivitis in clinical practice: Severity grading system and a treatment algorithm.
 

Author(s): Nikhil S Gokhale

Journal: Indian J Ophthalmol. 2016 Feb;64(2):145-8.

 

Vernal keratoconjunctivitis is an ocular allergy that is common in the pediatric age group. It is often chronic, severe, and nonresponsive to the available treatment options. Management of these children is difficult and often a dilemma for the practitioner. There is a need to simplify ...

Last Updated: 7 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Vernal keratoconjunctivitis" returned 2 free, full-text review articles on human participants. First 3 results:

Vernal keratoconjunctivitis: a major review.
 

Author(s): Sunil Kumar

Journal: Acta Ophthalmol. 2009 Mar;87(2):133-47.

 

Vernal keratoconjunctivitis (VKC) is a chronic, bilateral, at times asymmetrical, seasonally exacerbated, allergic inflammation of the ocular surface, involving tarsal and/or bulbar conjunctiva. Though the allergic nature of this entity has been accepted for a long time, the accumulation ...

Last Updated: 18 Mar 2009

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Systematic review and meta-analysis of randomised clinical trials on topical treatments for vernal keratoconjunctivitis.
 

Author(s): F Mantelli, M S Santos, T Petitti, R Sgrulletta, M Cortes, A Lambiase, S Bonini

Journal: Br J Ophthalmol. 2007 Dec;91(12):1656-61.

 

The aim of this study was to assess the efficacy of currently available topical drugs for vernal keratoconjunctivitis (VKC) through a meta-analysis of randomised clinical trials (RCTs).

Last Updated: 20 Nov 2007

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.