Vitiligo-associated multiple autoimmune disease susceptibility 1

Common Name(s)

Vitiligo-associated multiple autoimmune disease susceptibility 1

Generalized vitiligo is an autoimmune disease characterized by melanocyte loss, which results in patchy depigmentation of skin and hair, and is associated with an elevated risk of other autoimmune diseases. It is a genetically complex disorder involving multiple susceptibility genes and unknown environmental triggers. Patients with generalized vitiligo have elevated frequencies of other autoimmune diseases, suggesting that these diseases involve shared genetic components (summary by {3:Jin et al., 2010}). Genetic Heterogeneity of Vitiligo-Associated Multiple Autoimmune Disease Susceptibility Additional forms of vitiligo-associated multiple autoimmune disease susceptibility have been mapped to chromosomes 1p31 (VAMAS2, {607836}, associated with mutation in the FOXD3 gene, {611539}), 7 (VAMAS3; {608391}), 8 (VAMAS4; {608392}), 4 (VAMAS5; {609400}), and 6p21.3 (VAMAS6; {193200}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vitiligo-associated multiple autoimmune disease susceptibility 1" for support, advocacy or research.

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Scientific Literature

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 8 Jun 2017

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Last Updated: 10 Nov 2016

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A Study of INCB018424 Phosphate Cream in Subjects With Vitiligo
 

Status: Recruiting

Condition Summary: Vitiligo

 

Last Updated: 4 Jan 2018

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