Wet Age-related macular degeneration

Common Name(s)

Wet Age-related macular degeneration

Wet macular degeneration, or exudative macular degeneration, is an advanced form of age-related macular degeneration (AMD) which causes vision loss that gets worse over time (progressive). The macula is located in the central part of the back of the eye (retina) and helps a person see fine details and perform tasks such as reading and driving (sharp central vision). In all forms of AMD, damage to the macula leads to blurred or complete loss of central vision. In wet macular degeneration, abnormal blood vessels grow underneath the affected area of the macula (neovascularization). These new vessels are weak and leak blood and other important fluids. The affected areas then scar and affect vision.

Vision loss in wet macular degeneration is usually severe and rapid and only affects central vision, so affected people usually have normal vision on the edges of their eye (peripheral vision). Wet macular degeneration is the least common form of AMD, causing only 10 percent of all cases. Wet AMD typically starts off as dry macular degeneration, and then progresses to the more severe state.

The cause of wet macular degeneration is unclear. Age and genetics are the two most significant risk factors. Wet macular degeneration is usually found in adults over 55, and the risk increases with age. Smoking can also significantly increase the risk of developing the disorder. The condition is usually diagnosed by an eye doctor (ophthalmologist) who uses both a routine eye exam and special eye tests, such as optical coherence tomography (OCT), to look at images of the retina. There is no cure for wet macular degeneration, but good nutrition and protection from UV rays can help prevent symptoms. There are also medications available to help decrease or stop the formation of new blood vessels behind the macula. If you or a loved one has been diagnosed with AMD, talk to a doctor about all treatment options. Support groups can provide additional information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Wet Age-related macular degeneration" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Wet Age-related macular degeneration" returned 53 free, full-text research articles on human participants. First 3 results:

The impact of different anti-vascular endothelial growth factor treatment regimens on reducing burden for caregivers and patients with wet age-related macular degeneration in a single-center real-world Japanese setting.
 

Author(s): Tsukasa Hanemoto, Yusuke Hikichi, Norimasa Kikuchi, Tadahiko Kozawa

Journal:

 

To describe the burden associated with different anti-vascular endothelial growth factor (VEGF) treatment strategies for wet age-related macular degeneration (wAMD) in a real-word setting in Japan.

Last Updated: 31 Dec 1969

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Challenges Associated with Estimating Utility in Wet Age-Related Macular Degeneration: A Novel Regression Analysis to Capture the Bilateral Nature of the Disease.
 

Author(s): Robert Hodgson, Timothy Reason, David Trueman, Rose Wickstead, Jeanette Kusel, Adam Jasilek, Lindsay Claxton, Matthew Taylor, Ruth Pulikottil-Jacob

Journal: Adv Ther. 2017 Oct;34(10):2360-2370.

 

The estimation of utility values for the economic evaluation of therapies for wet age-related macular degeneration (AMD) is a particular challenge. Previous economic models in wet AMD have been criticized for failing to capture the bilateral nature of wet AMD by modelling visual acuity ...

Last Updated: 31 Dec 1969

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Plasma metabolomic study in Chinese patients with wet age-related macular degeneration.
 

Author(s): Dan Luo, Tingting Deng, Wei Yuan, Hui Deng, Ming Jin

Journal:

 

Age-related macular degeneration (AMD) is a leading disease associated with blindness. It has a high incidence and complex pathogenesis. We aimed to study the metabolomic characteristics in Chinese patients with wet AMD by analyzing the morning plasma of 20 healthy controls and 20 ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Wet Age-related macular degeneration" returned 7 free, full-text review articles on human participants. First 3 results:

Wet age related macular degeneration management and follow-up.
 

Author(s): Malciolu Radu Alexandru, Nica Maria Alexandra

Journal: Rom J Ophthalmol. ;60(1):9-13.

 

Age-related macular degeneration (AMD) is referred to as the leading cause of irreversible visual loss in developed countries, with a profound effect on the quality of life. The neovascular form of AMD is characterized by the formation of subretinal choroidal neovascularization, leading ...

Last Updated: 31 Dec 1969

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Guidelines for the Management of Wet Age-Related Macular Degeneration: Recommendations from a Panel of Greek Experts.
 

Author(s): Sofia Androudi, Anna Dastiridou, Nikolaos Pharmakakis, Maria Stefaniotou, Christos Kalogeropoulos, Chrysanthos Symeonidis, Alexandros Charonis, Miltiadis Tsilimbaris

Journal: Adv Ther. 2016 May;33(5):715-26.

 

To propose guidelines for the management of patients with wet age-related macular degeneration (wAMD), taking into account the results of large multicenter studies and clinical experience of retina experts.

Last Updated: 31 Dec 1969

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Intravitreal anti-VEGF injections for treating wet age-related macular degeneration: a systematic review and meta-analysis.
 

Author(s): Jun Ba, Run-Sheng Peng, Ding Xu, Yan-Hong Li, Hui Shi, Qianyi Wang, Jing Yu

Journal:

 

Age-related macular degeneration (AMD) is the main cause of blindness. Anti-vascular endothelial growth factor is used to prevent further neovascularization due to wet AMD. The purpose of this systematic review was to investigate the effect and protocol of anti-vascular endothelial ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluating of the Safety, Pharmacokinetics and Pharmacodynamics of QL1205 and Lucentis® in Patients With Wet AMD
 

Status: Recruiting

Condition Summary: Wet Age-related Macular Degeneration

 

Last Updated: 20 Oct 2017

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