Yellow fever

Common Name(s)

Yellow fever

Yellow fever is a viral infection spread by infected mosquitoes, common in South America and in sub-Saharan Africa. Once bitten, symptoms usually appear within 3 to 6 days, progressing in three stages. In stage 1, infection, symptoms include headaches, muscle and joint aches, fever, flushing, loss of appetite, vomiting, and jaundice. In stage 2, remission, fever and other symptoms go away. In stage 3, intoxication, problems with many organs occur, including heart, liver, and kidney failure, bleeding disorder, seizures, coma, and delirium. Yellow fever can cause severe damage leading to internal bleeding or death.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Yellow fever" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Yellow fever" returned 472 free, full-text research articles on human participants. First 3 results:

Fatal Yellow Fever in Travelers to Brazil, 2018.
 

Author(s): Davidson H Hamer, Kristina Angelo, Eric Caumes, Perry J J van Genderen, Simin A Florescu, Corneliu P Popescu, Cecilia Perret, Angela McBride, Anna Checkley, Jenny Ryan, Martin Cetron, Patricia Schlagenhauf

Journal:

 

Yellow fever virus is a mosquito-borne flavivirus that causes yellow fever, an acute infectious disease that occurs in South America and sub-Saharan Africa. Most patients with yellow fever are asymptomatic, but among the 15% who develop severe illness, the case fatality rate is 20%-60%. ...

Last Updated: 31 Dec 1969

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Development and characterization of a packaging cell line for pseudo-infectious yellow fever virus particle generation.
 

Author(s): Sabrina Ribeiro de Almeida Queiroz, José Valter Joaquim Silva Júnior, Andréa Nazaré Monteiro Rangel da Silva, Amanda Gomes de Oliveira Carvalho, Jefferson José da Silva Santos, Laura Helena Vega Gonzales Gil

Journal: Rev. Soc. Bras. Med. Trop.. ;51(1):66-70.

 

Pseudo-infectious yellow fever viral particles (YFV-PIVs) have been used to study vaccines and viral packaging. Here, we report the development of a packaging cell line, which expresses the YFV prM/E proteins.

Last Updated: 31 Dec 1969

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Metagenomic analysis reveals Hepatitis A virus in suspected yellow fever cases in Brazil.
 

Author(s): Liliane C Conteville, Ana Maria B de Filippis, Rita Maria R Nogueira, Marcos César L de Mendonça, Ana Carolina P Vicente

Journal: Mem. Inst. Oswaldo Cruz. 2018 Jan;113(1):66-67.

 

Using a metagenomic approach, we identified hepatitis A virus among cases of acute febrile illnesses that occurred in 2008-2012 in Brazil suspected as yellow fever. These findings reinforce the challenge facing routine clinical diagnosis in complex epidemiological scenarios.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Yellow fever" returned 21 free, full-text review articles on human participants. First 3 results:

T Cell-Mediated Immunity towards Yellow Fever Virus and Useful Animal Models.
 

Author(s): Alan M Watson, William B Klimstra

Journal:

 

The 17D line of yellow fever virus vaccines is among the most effective vaccines ever created. The humoral and cellular immunity elicited by 17D has been well characterized in humans. Neutralizing antibodies have long been known to provide protection against challenge with a wild-type ...

Last Updated: 31 Dec 1969

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Yellow fever vaccine-associated viscerotropic disease: current perspectives.
 

Author(s): Roger E Thomas

Journal:

 

To assess those published cases of yellow fever (YF) vaccine-associated viscerotropic disease that meet the Brighton Collaboration criteria and to assess the safety of YF vaccine with respect to viscerotropic disease.

Last Updated: 31 Dec 1969

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Questions regarding the safety and duration of immunity following live yellow fever vaccination.
 

Author(s): Ian J Amanna, Mark K Slifka

Journal: Expert Rev Vaccines. 2016 12;15(12):1519-1533.

 

The World Health Organization (WHO) and other health agencies have concluded that yellow fever booster vaccination is unnecessary since a single dose of vaccine confers lifelong immunity. Areas covered: We reviewed the clinical studies cited by health authorities in their investigation ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Immune Responses to Yellow Fever Vaccine
 

Status: Recruiting

Condition Summary: Yellow Fever Vaccine

 

Last Updated: 20 Sep 2017

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Last Updated: 20 Sep 2017

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Human Immune Responses to The Yellow Fever Virus Vaccine
 

Status: Recruiting

Condition Summary: Yellow Fever

 

Last Updated: 20 Sep 2017

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