Zygomycosis

Common Name(s)

Zygomycosis

Zygomycosis, also called mucormycosis, is a rare infection caused by a group of fungi called Mucoromycotina. These fungi are typically present in the soil and decaying organic matter such as leaves, compost piles, or rotten wood. Infection is more common among people who have weakened immune systems. People become infected by inhaling fungal spores, which can cause an infection to develop in the lungs, sinuses, eyes, and face. The fungus can also enter the skin through cuts, scrapes, or abrasions. Zygomycosis is not contagious and cannot be spread from person to person. Symptoms of Zygomycosis depend on where in the body the fungus is growing, but most commonly affects the sinuses or lungs. These symptoms can include fever, headache, and sinus pain. Lung infections from the fungus can cause fever and cough. When infected through the skin, symptoms can look like blisters or ulcers, and the infected tissue can turn black. Other symptoms include fever and tenderness, pain, heat, excessive redness, and swelling. If the infection is left untreated or not treated quickly, the fungus can spread to the rest of the body, and the infection is often fatal.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Zygomycosis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Zygomycosis" returned 84 free, full-text research articles on human participants. First 3 results:

Epidemiology of Zygomycosis: Analysis of National Data from Pathological Autopsy Cases in Japan.
 

Author(s): Yuhko Suzuki, Hikaru Kume, Tomiteru Togano, Hitoshi Ohto

Journal: Med Mycol J. 2017 ;58(3):E89-E95.

 

To identify recent trends in the frequency of zygomycosis in autopsy cases, we conducted epidemiological analysis every four years from 1989 to 2009 using national data reported in the "Annual of Pathological Autopsy Cases in Japan."

Last Updated: 31 Dec 1969

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Epidemiological aspects and clinical outcome of patients with Rhinocerebral zygomycosis: a survey in a referral hospital in Iran.
 

Author(s): Vida Bozorgi, Mahshid Talebitaher, Neda Shalbaf, Nima Radmanesh, Fatemeh Nasri, Mohammad Mostafa Ansari-Ramandi

Journal:

 

No comprehensive reports have been published on epidemiological status of Rhinocerebral zygomycosis infections and its outcome in our population, Hence, the current study came to address epidemiological characteristics as well as clinical outcome of patients with Rhinocerebral zygomycosis ...

Last Updated: 31 Dec 1969

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Fulminant zygomycosis of graft liver following liver transplantation.
 

Author(s): Pulkit Sethi, Dinesh Balakrishnan, Sudhindran Surendran, Zubair Umer Mohamed

Journal:

 

A 44-year-old man with hepatitis B virus (HBV)-related cirrhosis underwent living donor liver transplantation at our institute. Induction of immunosuppression was achieved with basiliximab, due to deranged renal function, and maintained with prednisolone, tacrolimus and mycophenolate ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Zygomycosis" returned 31 free, full-text review articles on human participants. First 3 results:

Acute cutaneous zygomycosis of the scalp: A case report and literature review.
 

Author(s): Abdulrahman Alseady, Salim Baharoon

Journal: J Infect Public Health. ;8(4):377-81.

 

Cutaneous zygomycosis is the third most common form of zygomycosis. However, scalp involvement is rare for this disease. In this study, we present a case of acute zygomycosis in a diabetic patient who was effectively treated with local debridement, amphotericin B lipid complex and posaconazole.

Last Updated: 31 Dec 1969

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Rhinocerebral zygomycosis with pansinusitis in a 14-year-old girl with type 1 diabetes: a case report and review of the literature.
 

Author(s): Annalisa di Coste, Francesco Costantino, Luigi Tarani, Vincenzo Savastano, Claudio Di Biasi, Laura Schiavi, Ilaria Ernesti, Taulant Melengu, Marzia Duse

Journal:

 

Zygomycosis is a rare life-threatening fungal infection affecting mostly patients with predisposing conditions such as diabetes mellitus, immunodeficiency, haemochromatosis or major trauma.

Last Updated: 31 Dec 1969

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Zygomycosis in children: disseminated infection caused by Cunninghamella bertholletiae.
 

Author(s): M José González-Abad, Mercedes Alonso Sanz

Journal: Arch. Bronconeumol.. 2013 Jan;49(1):35.

 

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Mucormycosis in ICU
 

Status: Recruiting

Condition Summary: Mucormycosis

 

Last Updated: 22 Dec 2017

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Endoscopic Surgical Treatment of Rhino-Sinusal Mucormycosis
 

Status: Recruiting

Condition Summary: Rhinocerebral Mucormycosis

 

Last Updated: 12 Aug 2016

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Clinical Study of AK1820 (Isavuconazonium Sulfate) for the Treatment of Deep Mycosis
 

Status: Not yet recruiting

Condition Summary: Deep Mycosis

 

Last Updated: 14 Mar 2018

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