dextro-Transposition of the great arteries, or d-Transposition of the great arteries, means that the two main arteries that carry blood away from the heart, the aorta and pulmonary artery, are reversed. Normally blood moves cyclically between the body, heart, and lungs. However, d-Transposition of the great arteries impairs this blood pathway because one artery cycles blood through the lungs, the other through the body, but they never interact so oxygen-rich blood never gets from the lungs to the body. Although the cause of the condition is unknown, risk factors include: rubella or other viral diseases during pregnancy, maternal age over 40, drinking alcohol or poor nutrition during pregnancy, maternal diabetes, and a family history of transposition of the great arteries. Symptoms may include: bluish color of the skin, shortness of breath, lack of appetite, and poor weight gain. This condition is usually diagnosed in the first few hours to weeks of life, and corrective surgery can be done to repair the arteries. If left untreated, d-transposition of the great arteries may cause heart failure or lung damage.