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Adrenoleukodystrophy

ALD
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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 1-10 of 16 results.
Lentiviral Gene Therapy for X-ALD
Status: Recruiting
Last Changed: Sep 19, 2019
First Received: Nov 01, 2018
Disease(s): X-linked Adrenoleukodystrophy
Intervention(s): Intracerebral LV gene therapy
Locations: Shenzhen Geno-immune Medical Institute, Shenzhen, Guangdong, China
Adrenoleukodystrophy National Registry Study
Status: Recruiting
Last Changed: Jul 01, 2020
First Received: Dec 31, 2018
Disease(s): ALD (Adrenoleukodystrophy), Adrenoleukodystrophy, Cerebral Adrenoleukodystrophy
Intervention(s): Medical Record Abstraction, Biospecimen Sample Collection
Locations: Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota, United States
Autologous Hematopoietic Stem Cell Gene Therapy for Metachromatic Leukodystrophy and Adrenoleukodystrophy
Status: Recruiting
Last Changed: Sep 24, 2015
First Received: Sep 24, 2015
Disease(s): Metachromatic Leukodystrophy, Adrenoleukodystrophy
Intervention(s): transduced CD34+ hematopoietic stem cell
Locations: Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, China
Clinical Study to Assess the Efficacy and Safety of Gene Therapy for the Treatment of Cerebral Adrenoleukodystrophy (CALD)
Status: Recruiting
Last Changed: Nov 02, 2020
First Received: Feb 25, 2019
Disease(s): Cerebral Adrenoleukodystrophy (CALD)
Intervention(s): Lenti-D; elivaldogene autotemcel
Locations: Lucile Packard Children's Hospital, Palo Alto, California, United States
Boston Children's Hospital/Massachusetts General Hospital, Boston, Massachusetts, United States
University of Minnesota, Minneapolis, Minnesota, United States
Hôpital Robert Debré, Paris, France
Universitätsklinikum Leipzig AöR, Leipzig, Germany
... and 4 other locations.
A Clinical Study in Male Pediatric Patients With Cerebral X-linked Adrenoleukodystrophy (Cald) to Assess the Effects of MIN-102 Treatment on Disease Progression Prior to Human Stem Cell Transplant (HSCT)
Status: Recruiting
Last Changed: Aug 27, 2020
First Received: Aug 27, 2020
Disease(s): Cerebral Adrenoleukodystrophy
Intervention(s): MIN-102
Locations: CHU Kremlin Bicêtre, Paris, France
Universitätsmedizin Göttingen Georg-August-Universität, Göttingen, Germany
Universitätsklinikum Hamburg-Eppendorf Klinik und Poliklinik für Kinder- und Jugendmedizin, Hamburg, Germany
Hospital Sant Joan de Déu, Barcelona, Spain
A Study to Prospectively Assess Disease Progression in Male Children With X-ALD
Status: Recruiting
Last Changed: Aug 08, 2018
First Received: Sep 12, 2017
Disease(s): X-Linked Adrenoleukodystrophy
Locations: Stanford University, Palo Alto, California, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
University of Pittsburgh, Pittsburgh, Pennsylvania, United States
Plasma Exchange With Albumin in AMN Patients
Status: Not yet recruiting
Last Changed: Mar 11, 2020
First Received: Mar 11, 2020
Disease(s): Adrenomyeloneuropathy, Adrenoleukodystrophy
Intervention(s): Albumin solution
Locations: Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain
Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (HaploHCT) Following Reduced Intensity Conditioning (RIC) for Selected High Risk Non-Malignant Diseases
Status: Recruiting
Last Changed: Mar 24, 2020
First Received: Dec 08, 2017
Disease(s): Sickle Cell Disease, Thalassemia, High Risk Hematologic Disorders, Cerebral Adrenoleukodystrophy, Inherited Metabolic Disorders
Intervention(s): Blood and Marrow Transplant
Locations: Masonic Caner Center at University of Minnesota, Minneapolis, Minnesota, United States
UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells
Status: Recruiting
Last Changed: Nov 24, 2020
First Received: Oct 02, 2014
Disease(s): Adrenoleukodystrophy, Batten Disease, Mucopolysaccharidosis II, Leukodystrophy, Globoid Cell, Leukodystrophy, Metachromatic, Neimann Pick Disease, Pelizaeus-Merzbacher Disease, Sandhoff Disease, Tay-Sachs Disease, Brain Diseases, Metabolic, Inborn, Alpha-Mannosidosis, Sanfilippo Mucopolysaccharidoses
Intervention(s): DUOC-01
Locations: Duke University Medical Center, Durham, North Carolina, United States
Multi-center Clinical Study on the Diagnosis and Treatment Management of Rare Neurological Disease in Children
Status: Not yet recruiting
Last Changed: Feb 11, 2020
First Received: Aug 28, 2018
Disease(s): Xlsma, DMD, X-ALD, TSC
Locations: Children's Hospital of Fudan University, Shanghai, China