# A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Finding useful health information on the Internet can be difficult, but we’re here to help. This page gathers quality information from trusted sources. You can learn more about the disease, visit handpicked websites, and find resources to help you in your daily life. Need more information? Click the menu on the left to find more!


Alpers Syndrome

Get Update

Review Articles from PubMed

Review articles summarize what is currently known about a disease. They discuss research previously published by others. The terms "Alpers Syndrome" returned 2 free, full-text review articles. First 2 results:
Alpers-Huttenlocher syndrome.
Last Updated: Mar 11, 2020

Alpers-Huttenlocher syndrome is an uncommon mitochondrial disease most often associated with mutations in the mitochondrial DNA replicase, polymerase-γ. Alterations in enzyme activity result in reduced levels or deletions in mitochondrial DNA. Phenotypic manifestations occur when ...

Alpers syndrome: progressive neuronal degeneration of children with liver disease.
Last Updated: Nov 16, 2017

Alpers syndrome was not clearly defined until the link between brain and liver disease was described. Alpers syndrome can now be clearly established as a disorder of oxidative metabolism related to mitochondrial dysfunction, and in most instances with an autosomal mode of inheritance. ...

Progressive neuronal degeneration of childhood with liver disease (Alpers-Huttenlocher syndrome): a personal review.
Last Updated: Feb 14, 2017

Thirty-two autopsied cases of progressive neuronal degeneration of childhood with liver disease are reviewed. The typical clinical course is intractable seizures and liver failure following a period of developmental delay and failure to thrive in early infancy, but some children first ...

Full PubMed Review articles matches at NCBI:
2 Free Review Articles 3 Review Articles

Editorials from PubMed

Editorial articles describe the outcome of a single study. They are the published results of original research. The terms "Alpers Syndrome" returned 0 free, full-text editorial articles. First 0 results:
Full PubMed Editorials matches at NCBI:
0 Free Editorials 1 Editorials

Research Articles from PubMed

Research articles describe the outcome of a single study. They are the published results of original research. The terms "Alpers Syndrome" returned 10 free, full-text research articles. First few results:
Specific EEG markers in POLG1 Alpers' syndrome.
Last Updated: Aug 13, 2019

To examine whether rhythmic high-amplitude delta with superimposed (poly)spikes (RHADS) in EEG allow a reliable early diagnosis of Alpers-Huttenlocher syndrome (AHS) and contribute to recognition of this disease.

Dissecting the neuronal vulnerability underpinning Alpers' syndrome: a clinical and neuropathological study.
Last Updated: Jul 26, 2020

Alpers' syndrome is an early-onset neurodegenerative disorder often caused by biallelic pathogenic variants in the gene encoding the catalytic subunit of polymerase-gamma (POLG) which is essential for mitochondrial DNA (mtDNA) replication. Alpers' syndrome is characterized by intractable ...

Full PubMed Research articles matches at NCBI:
10 Free Research Articles 42 Research Articles