Chromosome 10, trisomy 10p is a rare genetic condition. This condition results from a mutation or error in a person’s DNA or genes. This can cause odd facial features such as a large forehead, small face, or eyebrows that are fine, arched, and extend to the temples. It may also cause intellectual disability and movement disabilities. Although there is currently no cure for chromosome 10, trisomy 10p there are various resources to help manage the condition and treat birth defects. Doctors seek help from various therapists and community services to provide support and care for families affected by chromosome 10, trisomy 10p. Prenatal diagnosis may be posible after the birth of the first affected child or after warning signs from an ultrasound. Around 50 cases have been described so far in literature.