Chromosome 12, 12p trisomy, also known as trisomy 12p, is a rare genetic condition. This condition results from a mutation or error in a person’s DNA or genes. This can cause birth defects such as abnormally short and wide hands, diminished muscle tone, or deformities of the head and face. In addition, it may also cause intellectual disability and abnormal growth before and after birth. Although there is currently no cure for chromosome 12, 12p trisomy, there are various resources to help manage the condition and treat birth defects. Doctors may recommend corrective surgery for birth defects affecting the head and face. Doctors seek help from various therapists and community services to provide support and care for families affected by chromosome 12, 12p trisomy.