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Chronic Graft versus Host Disease

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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 1-10 of 65 results.
A Study of Itacitinib for the Treatment of Chronic Graft Versus Host Disease (cGVHD)
Status: Recruiting
Last Changed: Jun 24, 2020
First Received: Dec 16, 2019
Disease(s): Chronic Graft-versus-host-disease
Intervention(s): Itacitinib
Locations: Colorado Blood Cancer Institute, Denver, Colorado, United States
The Sarah Cannon Research Institute, Nashville, Tennessee, United States
South Austin Medical Center, Austin, Texas, United States
Texas Transplant Institute, San Antonio, Texas, United States
Phase 1/2 Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects With Chronic Graft Versus Host Disease (cGVHD)
Status: Recruiting
Last Changed: May 20, 2020
First Received: Dec 31, 2018
Disease(s): Chronic Graft Versus Host Disease
Intervention(s): Ibrutinib
Locations: City of Hope, Duarte, California, United States
Rady Children's Hospital, San Diego, California, United States
University of California, San Francisco, California, United States
Children's Hospital, Aurora, Colorado, United States
Children's National Medical Center, Washington, District of Columbia, United States
... and 44 other locations.
Itacitinib (INCB039110) and Extracorporeal Photopheresis (ECP) for First-Line Treatment in Chronic Graft Versus Host Disease
Status: Not yet recruiting
Last Changed: Jun 24, 2020
First Received: Jun 24, 2020
Disease(s): Chronic Graft-versus-host-disease
Intervention(s): Itacitinib, Extracorporeal Photopheresis (ECP)
Efficacy and Safety of SCM-CGH in Patients With Steroid-Refractory or Dependent Chronic Graft-Versus-Host Disease
Status: Recruiting
Last Changed: Dec 06, 2019
First Received: Dec 06, 2019
Disease(s): Chronic Graft-versus-host-disease
Intervention(s): SCM-CGH, Placebo
Locations: National Cancer Center, Goyang-si, Gyeonggi-do, Korea, Republic of
Inha University Hospital, Incheon, Korea, Republic of
Seoul National University Seoul, Seoul, Korea, Republic of
Severance Hospital, Seoul, Korea, Republic of
Asan Medical Center, Seoul, Korea, Republic of
... and 3 other locations.
GRAVITAS-309: Itacitinib or Placebo in Combination With Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease
Status: Recruiting
Last Changed: Sep 25, 2019
First Received: Jul 12, 2018
Disease(s): Chronic Graft-versus-host Disease
Intervention(s): Itacitinib, Placebo, Methylprednisolone, Prednisone
Locations: The University of Arizona Cancer Center, Tucson, Arizona, United States
City of Hope, Duarte, California, United States
Georgia Cancer Center at Augusta, Augusta, Georgia, United States
(USO) Illinois Cancer Specialists, Niles, Illinois, United States
Indiana University - Melvin and Bren Simon Cancer Center IUSCC, Indianapolis, Indiana, United States
... and 40 other locations.
Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease
Status: Recruiting
Last Changed: Jul 17, 2020
First Received: Feb 06, 2018
Disease(s): Chronic Graft Versus Host Disease cGVHD
Intervention(s): AMG 592
Locations: Research Site, Duarte, California, United States
Research Site, Tampa, Florida, United States
Research Site, Atlanta, Georgia, United States
Research Site, Boston, Massachusetts, United States
Research Site, Rochester, Minnesota, United States
... and 10 other locations.
Multiple Donor Treg DLI for Severe Refractory Chronic GVHD
Status: Recruiting
Last Changed: Jan 18, 2019
First Received: Apr 22, 2016
Disease(s): Chronic Graft Versus Host Disease
Intervention(s): T reg DLI
Locations: University Hospital St. Orsola-Malpighi Polyclinic, Bologna, BO, Italy
Leflunomide in Treating Patients With Steroid Dependent Chronic Graft Versus Host Disease
Status: Recruiting
Last Changed: May 21, 2020
First Received: Dec 27, 2019
Disease(s): Chronic Graft Versus Host Disease, Steroid Refractory Graft Versus Host Disease
Intervention(s): Leflunomide
Locations: City of Hope Medical Center, Duarte, California, United States
Extracorporeal Photopheresis Using Theraflex ECP™ for Patients With Refractory Chronic Graft Versus Host Disease (cGVHD)
Status: Recruiting
Last Changed: Mar 20, 2017
First Received: Mar 20, 2017
Disease(s): Refractory Chronic Graft Versus Host Disease (cGVHD)
Intervention(s): Photopheresis Theraflex ECP™
Locations: Ziekenhuis Netwerk Antwerpen, Antwerpen, Belgium
AZ Sint-Jan Brugge, Brugge, Belgium
Institut Jules Bordet, Brussels, Belgium
Universitair Ziekenhuis Antwerpen, Edegem, Belgium
Universitair Ziekenhuis Gent, Gent, Belgium
... and 4 other locations.
Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation
Status: Recruiting
Last Changed: Oct 22, 2020
First Received: May 03, 2016
Disease(s): Chronic Graft vs Host Disease, Chronic Graft-Versus-Host Disease
Intervention(s): Baricitinib
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland, United States